Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Przemyslaw, Leszek"'
Autor:
Jacqueline Heger, Stefan Partsch, Claudia Harjung, Zoltán V. Varga, Tamás Baranyai, Johannes Weiß, Lea Kremer, Fabian Locquet, Przemyslaw Leszek, Bence Ágg, Bettina Benczik, Péter Ferdinandy, Rainer Schulz, Gerhild Euler
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 401 (2023)
Cardiac hypertrophy resulting from sympathetic nervous system activation triggers the development of heart failure. The transcription factor Y-box binding protein 1 (YB-1) can interact with transcription factors involved in cardiac hypertrophy and ma
Externí odkaz:
https://doaj.org/article/43a811068dde42149ee976eccc024c5a
Autor:
Alisia Madè, Alessia Bibi, Jose Manuel Garcia-Manteiga, Anna Sofia Tascini, Santiago Nicolas Piella, Roman Tikhomirov, Christine Voellenkle, Carlo Gaetano, Przemyslaw Leszek, Serenella Castelvecchio, Lorenzo Menicanti, Fabio Martelli, Simona Greco
Publikováno v:
Cells, Vol 12, Iss 21, p 2578 (2023)
Noncoding RNAs (ncRNAs), which include circular RNAs (circRNAs) and microRNAs (miRNAs), regulate the development of cardiovascular diseases (CVD). Notably, circRNAs can interact with miRNAs, influencing their specific mRNA targets’ levels and shapi
Externí odkaz:
https://doaj.org/article/ab68ca85e619417b8427ed877fe9797e
Autor:
Huseyin Firat, Lu Zhang, Shounak Baksi, Przemyslaw Leszek, Eric Schordan, Samir Ounzain, Jan Kottwitz, Dimitri Patriki, Bettina Heidecker, Thomas F. Lüscher, Thierry Pedrazzini, Yvan Devaux
Publikováno v:
Heliyon, Vol 9, Iss 1, Pp e13087- (2023)
Summary: Cardiovascular disorders such as heart failure are leading causes of mortality. Patient stratification via identification of novel biomarkers could improve management of cardiovascular diseases of complex etiologies. Long-noncoding RNAs (lnc
Externí odkaz:
https://doaj.org/article/a86ef368bcf540359ac020a48e354359
Autor:
Imre Vörös, Éva Sághy, Krisztina Pohóczky, András Makkos, Zsófia Onódi, Gábor B. Brenner, Tamás Baranyai, Bence Ágg, Barnabás Váradi, Ágnes Kemény, Przemyslaw Leszek, Anikó Görbe, Zoltán V. Varga, Zoltán Giricz, Rainer Schulz, Zsuzsanna Helyes, Péter Ferdinandy
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Little is known about the role of the neuropeptide somatostatin (SST) in myocardial ischemia/reperfusion injury and cardioprotection. Here, we investigated the direct cardiocytoprotective effect of SST on ischemia/reperfusion injury in cardiomyocyte
Externí odkaz:
https://doaj.org/article/dcbc88f896f543ad8ae2da1ca762c860
Autor:
Imre Vörös, Zsófia Onódi, Viktória Éva Tóth, Tamás G. Gergely, Éva Sághy, Anikó Görbe, Ágnes Kemény, Przemyslaw Leszek, Zsuzsanna Helyes, Péter Ferdinandy, Zoltán V. Varga
Publikováno v:
Biomedicines, Vol 10, Iss 7, p 1573 (2022)
Dipeptidyl-peptidase-4 (DPP4) inhibitors are novel medicines for diabetes. The SAVOR-TIMI-53 clinical trial revealed increased heart-failure-associated hospitalization in saxagliptin-treated patients. Although this side effect could limit therapeutic
Externí odkaz:
https://doaj.org/article/b9b1068e730841bcbfb1bdb37cef836e
Autor:
Mélanie Vausort, Magdalena Niedolistek, Andrew I. Lumley, Marta Oknińska, Aleksandra Paterek, Michał Mączewski, Xiangyi Dong, Christian Jäger, Carole L. Linster, Przemyslaw Leszek, Yvan Devaux
Publikováno v:
Cells, Vol 11, Iss 15, p 2271 (2022)
Development of heart failure (HF) after myocardial infarction (MI) is responsible for premature death. Complex cellular and molecular mechanisms are involved in this process. A number of studies have linked the epitranscriptomic RNA modification N6-m
Externí odkaz:
https://doaj.org/article/f2f65b98c40f4889ace49127e8895882
Autor:
Dóra Szabó, Zsolt Sárszegi, Beáta Polgár, Éva Sághy, Dóra Reglődi, Tünde Tóth, Zsófia Onódi, Przemyslaw Leszek, Zoltán V. Varga, Zsuzsanna Helyes, Ágnes Kemény, Péter Ferdinandy, Andrea Tamás
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 3715 (2022)
Pituitary adenylate cyclase activating polypeptide-38 (PACAP-38) is a multifunctional neuropeptide, which may play a role in cardioprotection. However, little is known about the presence of PACAP-38 in heart failure (HF) patients. The aim of our stud
Externí odkaz:
https://doaj.org/article/f42f53f9795a46be8db46dfd4cd71f43
Autor:
Adrián Szobi, Eva Gonçalvesová, Zoltán V. Varga, Przemyslaw Leszek, Mariusz Kuśmierczyk, Michal Hulman, Ján Kyselovič, Péter Ferdinandy, Adriana Adameová
Publikováno v:
Journal of Translational Medicine, Vol 15, Iss 1, Pp 1-7 (2017)
Abstract Background Cell loss and subsequent deterioration of contractile function are hallmarks of chronic heart failure (HF). While apoptosis has been investigated as a participant in the progression of HF, it is unlikely that it accounts for the t
Externí odkaz:
https://doaj.org/article/efd8dfb982a44a71b3d1ca05a8eb4b41
Autor:
Zsófia Onódi, Tamás Visnovitz, Bernadett Kiss, Szabolcs Hambalkó, Anna Koncz, Bence Ágg, Barnabás Váradi, Viktória É. Tóth, Regina N. Nagy, Tamás G. Gergely, Dorottya Gergő, András Makkos, Csilla Pelyhe, Nóra Varga, Dóra Reé, Ágota Apáti, Przemyslaw Leszek, Tamás Kovács, Nándor Nagy, Péter Ferdinandy, Edit I. Buzás, Anikó Görbe, Zoltán Giricz, Zoltán V. Varga
Publikováno v:
Journal of Molecular and Cellular Cardiology
Cardiac cell lines and primary cells are widely used in cardiovascular research. Despite increasing number of publications using these models, comparative characterization of these cell lines has not been performed, therefore, their limitations are u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26b1324109672c1d3e14fdad28f49623
https://doi.org/10.1016/j.yjmcc.2021.12.007
https://doi.org/10.1016/j.yjmcc.2021.12.007
Autor:
Zoltán V. Varga, Márton Pipicz, Júlia A. Baán, Tamás Baranyai, Gábor Koncsos, Przemyslaw Leszek, Mariusz Kuśmierczyk, Fátima Sánchez-Cabo, Pablo García-Pavía, Gábor J. Brenner, Zoltán Giricz, Tamás Csont, Luca Mendler, Enrique Lara-Pezzi, Pál Pacher, Péter Ferdinandy
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Increased oxidative stress is a major contributor to the development and progression of heart failure, however, our knowledge on the role of the distinct NADPH oxidase (NOX) isoenzymes, especially on NOX4 is controversial. Therefore, we aimed to char
Externí odkaz:
https://doaj.org/article/77dab2edf454413e93c231c8ce8b47ad