Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Przemysław Dutka"'
Autor:
Szymon P. Kordon, Przemysław Dutka, Justyna M. Adamska, Sumit J. Bandekar, Katherine Leon, Satchal K. Erramilli, Brock Adams, Jingxian Li, Anthony A. Kossiakoff, Demet Araç
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Adhesion GPCRs have numerous functions, ligands and isoforms. Here, Kordon et al. report synthetic antibodies that both modulate aGPCR signaling in an isoform-specific manner, and break receptor interactions in a ligand-specific manner
Externí odkaz:
https://doaj.org/article/f09e75b26ec2499fb1db91e3ee673ec0
Autor:
Doulin C. Shepherd, Mohammed Kaplan, Naveen Vankadari, Ki Woo Kim, Charles L. Larson, Przemysław Dutka, Paul A. Beare, Edward Krzymowski, Robert A. Heinzen, Grant J. Jensen, Debnath Ghosal
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107210- (2023)
Summary: Coxiella burnetii is an obligate zoonotic bacterium that targets macrophages causing a disease called Q fever. It has a biphasic developmental life cycle where the extracellular and metabolically inactive small cell variant (SCV) transforms
Externí odkaz:
https://doaj.org/article/27c86346303a4fe4bee530fa4804c8f2
Autor:
Somnath Mukherjee, Satchal K. Erramilli, Mark Ammirati, Frances J. D. Alvarez, Kimberly F. Fennell, Michael D. Purdy, Blazej M. Skrobek, Katarzyna Radziwon, John Coukos, Yanyong Kang, Przemysław Dutka, Xiang Gao, Xiayang Qiu, Mark Yeager, H. Eric Xu, Seungil Han, Anthony A. Kossiakoff
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Single particle cryo-electron microscopy of membrane proteins is limited by their small size and difficulty to orient. Here the authors generate recombinant antibodies against the 12 kDa fusion partner BRIL domain from apocytochrome b562 to use them
Externí odkaz:
https://doaj.org/article/c4e601bd5c28456ba07689558d4667e5
Autor:
Przemysław Dutka, Lauren Ann Metskas, Robert C. Hurt, Hossein Salahshoor, Ting-Yu Wang, Dina Malounda, George Lu, Tsui-Fen Chou, Mikhail G. Shapiro, Grant J. Jensen
SUMMARYGas vesicles (GVs) are gas-filled protein nanostructures employed by several species of bacteria and archaea as flotation devices to enable access to optimal light and nutrients. The unique physical properties of GVs have led to their use as g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30a829af8b0f47dc85b42425bb3ffc58
https://resolver.caltech.edu/CaltechAUTHORS:20230628-257245000.39
https://resolver.caltech.edu/CaltechAUTHORS:20230628-257245000.39
Autor:
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Grant J. Jensen
Publikováno v:
bioRxiv
TheLegionella pneumophilaDot/Icm type IV secretion system (T4SS) delivers effector proteins into host cells during infection. Despite its significance as a potential drug target, our current understanding of its atomic structure is limited to isolate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1f6f3edc9618d9b93da76820d61f89e
https://europepmc.org/articles/PMC10055428/
https://europepmc.org/articles/PMC10055428/
Autor:
Robert C. Hurt, Marjorie T. Buss, Mengtong Duan, Katie Wong, Mei Yi You, Daniel P. Sawyer, Margaret B. Swift, Przemysław Dutka, Pierina Barturen-Larrea, David R. Mittelstein, Zhiyang Jin, Mohamad H. Abedi, Arash Farhadi, Ramya Deshpande, Mikhail G. Shapiro
Publikováno v:
Nature Biotechnology.
Ultrasound allows imaging at a much greater depth than optical methods, but existing genetically encoded acoustic reporters for in vivo cellular imaging have been limited by poor sensitivity, specificity and in vivo expression. Here we describe two a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::736381010f242442cc50cd50d613835b
https://doi.org/10.1038/s41587-022-01581-y
https://doi.org/10.1038/s41587-022-01581-y
Autor:
Mohammed Kaplan, Doulin C. Shepherd, Naveen Vankadari, Ki Woo Kim, Charles L. Larson, Przemysław Dutka, Paul A. Beare, Edward Krzymowski, Robert A. Heinzen, Grant J. Jensen, Debnath Ghosal
Coxiella burnetii is an obligate zoonotic bacterium that targets macrophages to cause a disease known as Q fever. It has a biphasic developmental lifecycle where the extracellular and metabolically inactive small cell variant (SCV) transforms, under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ee964f1af71346a17f499fdcefc0e65
https://doi.org/10.1101/2022.08.23.505044
https://doi.org/10.1101/2022.08.23.505044
Autor:
Szymon P. Kordon, Przemysław Dutka, Justyna M. Adamska, Sumit J. Bandekar, Katherine Leon, Brock Adams, Jingxian Li, Anthony A. Kossiakoff, Demet Araç
Adhesion G protein-coupled receptors (aGPCRs) are cell-surface proteins with large extracellular regions that bind to multiple ligands to regulate key biological functions including neurodevelopment and organogenesis. Modulating a single function of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83107c827ba7dbb5353221dcc89d1cc0
https://doi.org/10.1101/2022.07.20.500857
https://doi.org/10.1101/2022.07.20.500857
Autor:
Hossein Salahshoor, Yuxing Yao, Przemysław Dutka, Nivin N. Nyström, Zhiyang Jin, Ellen Min, Dina Malounda, Grant J. Jensen, Michael Ortiz, Mikhail G. Shapiro
SUMMARYAcoustic reporter genes based on gas vesicles (GVs) have enabled the use of ultrasound to noninvasively visualize cellular function in vivo. The specific detection of GV signals relative to background acoustic scattering in tissues is facilita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f7aa6b81fd8b79341d6e75e226b5d07
https://doi.org/10.1101/2022.06.27.497663
https://doi.org/10.1101/2022.06.27.497663
Subtomogram averages and integrative model of GvpA/GvpC described in our preprint: Dutka et al.,Structure ofAnabaena flos-aquaegas vesicles revealed by cryo-ET,BioRxiv (2022).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2659::e5647fb19ad5e766d3556773d4cdb861
https://zenodo.org/record/6820642
https://zenodo.org/record/6820642