Particulate matter from both heavy fuel oil and diesel fuel shipping emissions show strong biological effects on human lung cells at realistic and comparable in vitro exposure conditions

Autor: Oeder, S., Kanashova, T., Sippula, O., Sapcariu, S.C., Streibel, T., Arteaga-Salas, J.M., Passig, J., Dilger, M., Paur, H.R., Schlager, C., Muelhopt, S., Diabate, S., Weiss, C., Stengel, B., Rabe, R., Harndorf, H., Torvela, T., Jokiniemi, J.K., Hirvonen, M.R., Schmidt-Weber, C., Traidl-Hoffmann, C., BeruBe, K.A., Wlodarczyk, A.J., Prytherch, Z., Michalke, B., Krebs, T., Prevot, A.S.H., Kelbg, M., Tiggesbaeumker, J., Karg, E., Jakobi, G., Scholtes, S., Schnelle-Kreis, J., Lintelmann, J., Matuschek, G., Sklorz, M., Klingbeil, S., Orasche, J., Richthammer, P., Mueller, L., Elsasser, M., Reda, A., Groeger, T., Weggler, B., Schwemer, T., Czech, H., Rueger, C.P., Abbaszade, G., Radischat, C., Hiller, K., Buters, J.T.M., Dittmar, G., Zimmermann, R.

Publikováno v: PLoS ONE. San Franscisco, CA: Public Library of Science (2015).
PLoS ONE
PLoS ONE, 10 (6)
PLoS one, 10 (6), e126536
PLoS ONE, Vol 10, Iss 6, p e0126536 (2015)
PLoS ONE 10:e0126536 (2015)

Background\ud \ud Ship engine emissions are important with regard to lung and cardiovascular diseases especially in coastal regions worldwide. Known cellular responses to combustion particles include oxidative stress and inflammatory signalling.\ud \

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::475d4cb9350a7161fa8b3fb7148bde27
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/82489

Particulate matter from both heavy fuel oil and diesel fuel shipping emissions show strong biological effects on human lung cells at realistic and comparable in vitro exposure conditions

Autor: Oeder, S., Kanashova, T., Sippula, O., Sapcariu, S.C., Streibel, T., Arteaga-Salas, J.M., Passig, J., Dilger, M., Paur, H.R., Schlager, C., Mülhopt, S., Diabate, S., Weiss, C., Stengel, B., Rabe, R., Harndorf, H., Torvela, T., Jokiniemi, J.K., Hirvonen, M.R., Schmidt-Weber, C., Traidl-Hoffmann, C., BeruBe, K.A., Wlodarczyk, J., Prytherch, Z., Michalke, B., Krebs, T., Prevot, A.S.H., Kelbg, M., Tiggesbäumker, J., Karg, E., Jakobi, G., Scholtes, S., Schnelle-Kreis, J., Lintelmann, J., Matuschek, G., Sklorz, M., Klingbeil, S., Orasche, J., Richthammer, P., Müller, L., Elsasser, M., Reda, A., Gröger, T., Weggler, B., Czech, H., Rüger, C.P., Abbaszade, G., Radischat, C., Hiller, K., Buters, J.T.M., Dittmar, G., Zimmermann, R., Schwemer, T.

Background: Ship engine emissions are important with regard to lung and cardiovascular diseases especially in coastal regions worldwide. Known cellular responses to combustion particles include oxidative stress and inflammatory signalling. Objectives

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dd1fb20356123eefc5dedd73f67283ec

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Particulate matter from both heavy fuel oil and diesel fuel shipping emissions show strong biological effects on human lung cells at realistic and comparable in vitro exposure conditions.

Autor: Oeder S; HICE-Helmholtz Virtual Institute of Complex Molecular Systems in Environmental Health-Aerosols and Health, www.hice-vi.eu, Neuherberg, Rostock, Munich, Karlsruhe, Berlin, Waldkirch, Germany, Kuopio, Finland, Cardiff, UK, Esch-Belval, Luxembourg; Center of Allergy and Environment (ZAUM), Helmholtz Zentrum München and Technische Universität München, Member of the German Center for Lung Research (DZL), Munich, Germany; CK-CARE, Christine Kühne Center for Allergy Research and Education, Davos, Switzerland., Kanashova T; HICE-Helmholtz Virtual Institute of Complex Molecular Systems in Environmental Health-Aerosols and Health, www.hice-vi.eu, Neuherberg, Rostock, Munich, Karlsruhe, Berlin, Waldkirch, Germany, Kuopio, Finland, Cardiff, UK, Esch-Belval, Luxembourg; Mass Spectrometry Core Unit, Max Delbrück Center for Molecular Medicine Berlin-Buch, Germany., Sippula O; HICE-Helmholtz Virtual Institute of Complex Molecular Systems in Environmental Health-Aerosols and Health, www.hice-vi.eu, Neuherberg, Rostock, Munich, Karlsruhe, Berlin, Waldkirch, Germany, Kuopio, Finland, Cardiff, UK, Esch-Belval, Luxembourg; University of Eastern Finland, Department of Environmental Science, P.O. Box 1627, FI-70211 Kuopio, Finland., Sapcariu SC; HICE-Helmholtz Virtual Institute of Complex Molecular Systems in Environmental Health-Aerosols and Health, www.hice-vi.eu, Neuherberg, Rostock, Munich, Karlsruhe, Berlin, Waldkirch, Germany, Kuopio, Finland, Cardiff, UK, Esch-Belval, Luxembourg; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, L-4362 Esch-Belval, Luxembourg., Streibel T; HICE-Helmholtz Virtual Institute of Complex Molecular Systems in Environmental Health-Aerosols and Health, www.hice-vi.eu, Neuherberg, Rostock, Munich, Karlsruhe, Berlin, Waldkirch, Germany, Kuopio, Finland, Cardiff, UK, Esch-Belval, Luxembourg; Joint Mass Spectrometry Centre, Chair of Analytical Chemistry, Institute of Chemistry, University Rostock, Rostock, Germany; Joint Mass Spectrometry Centre, CMA-Comprehensive Molecular Analytics, Helmholtz Zentrum München, Neuherberg, Germany., Arteaga-Salas JM; HICE-Helmholtz Virtual Institute of Complex Molecular Systems in Environmental Health-Aerosols and Health, www.hice-vi.eu, Neuherberg, Rostock, Munich, Karlsruhe, Berlin, Waldkirch, Germany, Kuopio, Finland, Cardiff, UK, Esch-Belval, Luxembourg; Joint Mass Spectrometry Centre, CMA-Comprehensive Molecular Analytics, Helmholtz Zentrum München, Neuherberg, Germany., Passig J; HICE-Helmholtz Virtual Institute of Complex Molecular Systems in Environmental Health-Aerosols and Health, www.hice-vi.eu, Neuherberg, Rostock, Munich, Karlsruhe, Berlin, Waldkirch, Germany, Kuopio, Finland, Cardiff, UK, Esch-Belval, Luxembourg; Joint Mass Spectrometry Centre, Chair of Analytical Chemistry, Institute of Chemistry, University Rostock, Rostock, Germany., Dilger M; HICE-Helmholtz Virtual Institute of Complex Molecular Systems in Environmental Health-Aerosols and Health, www.hice-vi.eu, Neuherberg, Rostock, Munich, Karlsruhe, Berlin, Waldkirch, Germany, Kuopio, Finland, Cardiff, UK, Esch-Belval, Luxembourg; Institute for Technical Chemistry (ITC), Karlsruhe Institute of Technology, Campus North, Karlsruhe, Germany; Institute of Toxicology and Genetics (ITG), Karlsruhe Institute of Technology, Campus North, Karlsruhe, Germany., Paur HR; HICE-Helmholtz Virtual Institute of Complex Molecular Systems in Environmental Health-Aerosols and Health, www.hice-vi.eu, Neuherberg, Rostock, Munich, Karlsruhe, Berlin, Waldkirch, Germany, Kuopio, Finland, Cardiff, UK, Esch-Belval, Luxembourg; Institute for Technical Chemistry (ITC), Karlsruhe Institute of Technology, Campus North, Karlsruhe, Germany., Schlager C; HICE-Helmholtz Virtual Institute of Complex Molecular Systems in Environmental Health-Aerosols and Health, www.hice-vi.eu, Neuherberg, Rostock, Munich, Karlsruhe, Berlin, Waldkirch, Germany, Kuopio, Finland, Cardiff, UK, Esch-Belval, Luxembourg; Institute for Technical Chemistry (ITC), Karlsruhe Institute of Technology, Campus North, Karlsruhe, Germany., Mülhopt S; HICE-Helmholtz Virtual Institute of Complex Molecular Systems in Environmental Health-Aerosols and Health, www.hice-vi.eu, Neuherberg, Rostock, Munich, Karlsruhe, Berlin, Waldkirch, Germany, Kuopio, Finland, Cardiff, UK, Esch-Belval, Luxembourg; Institute for Technical Chemistry (ITC), Karlsruhe Institute of Technology, Campus North, Karlsruhe, Germany., Diabaté S; HICE-Helmholtz Virtual Institute of Complex Molecular Systems in Environmental Health-Aerosols and Health, www.hice-vi.eu, Neuherberg, Rostock, Munich, Karlsruhe, Berlin, Waldkirch, Germany, Kuopio, Finland, Cardiff, UK, Esch-Belval, Luxembourg; Institute of Toxicology and Genetics (ITG), Karlsruhe Institute of Technology, Campus North, Karlsruhe, Germany., Weiss C; HICE-Helmholtz Virtual Institute of Complex Molecular Systems in Environmental Health-Aerosols and Health, www.hice-vi.eu, Neuherberg, Rostock, Munich, Karlsruhe, Berlin, Waldkirch, Germany, Kuopio, Finland, Cardiff, UK, Esch-Belval, Luxembourg; Institute of Toxicology and Genetics (ITG), Karlsruhe Institute of Technology, Campus North, Karlsruhe, Germany., Stengel B; HICE-Helmholtz Virtual Institute of Complex Molecular Systems in Environmental Health-Aerosols and Health, www.hice-vi.eu, Neuherberg, Rostock, Munich, Karlsruhe, Berlin, Waldkirch, Germany, Kuopio, Finland, Cardiff, UK, Esch-Belval, Luxembourg; Chair of Piston Machines and Internal Combustion Engines, University Rostock, Rostock, Germany., Rabe R; HICE-Helmholtz Virtual Institute of Complex Molecular Systems in Environmental Health-Aerosols and Health, www.hice-vi.eu, Neuherberg, Rostock, Munich, Karlsruhe, Berlin, Waldkirch, Germany, Kuopio, Finland, Cardiff, UK, Esch-Belval, Luxembourg; Chair of Piston Machines and Internal Combustion Engines, University Rostock, Rostock, Germany., Harndorf H; HICE-Helmholtz Virtual Institute of Complex Molecular Systems in Environmental Health-Aerosols and Health, www.hice-vi.eu, Neuherberg, Rostock, Munich, Karlsruhe, Berlin, Waldkirch, Germany, Kuopio, Finland, Cardiff, UK, Esch-Belval, Luxembourg; Chair of Piston Machines and Internal Combustion Engines, University Rostock, Rostock, Germany., Torvela T; University of Eastern Finland, Department of Environmental Science, P.O. Box 1627, FI-70211 Kuopio, Finland., Jokiniemi JK; HICE-Helmholtz Virtual Institute of Complex Molecular Systems in Environmental Health-Aerosols and Health, www.hice-vi.eu, Neuherberg, Rostock, Munich, Karlsruhe, Berlin, Waldkirch, Germany, Kuopio, Finland, Cardiff, UK, Esch-Belval, Luxembourg; University of Eastern Finland, Department of Environmental Science, P.O. Box 1627, FI-70211 Kuopio, Finland; VTT Technical Research Centre of Finland, P.O. Box 1000, FI-02044 VTT, Espoo, Finland., Hirvonen MR; HICE-Helmholtz Virtual Institute of Complex Molecular Systems in Environmental Health-Aerosols and Health, www.hice-vi.eu, Neuherberg, Rostock, Munich, Karlsruhe, Berlin, Waldkirch, Germany, Kuopio, Finland, Cardiff, UK, Esch-Belval, Luxembourg; University of Eastern Finland, Department of Environmental Science, P.O. Box 1627, FI-70211 Kuopio, Finland; National Institute for Health and Welfare, Department of Environmental Health, P.O. Box 95, FI-70701, Kuopio, Finland., Schmidt-Weber C; Center of Allergy and Environment (ZAUM), Helmholtz Zentrum München and Technische Universität München, Member of the German Center for Lung Research (DZL), Munich, Germany., Traidl-Hoffmann C; CK-CARE, Christine Kühne Center for Allergy Research and Education, Davos, Switzerland; Institute of environmental medicine, UNIKA-T, Technische Universität, Munich, Germany., BéruBé KA; HICE-Helmholtz Virtual Institute of Complex Molecular Systems in Environmental Health-Aerosols and Health, www.hice-vi.eu, Neuherberg, Rostock, Munich, Karlsruhe, Berlin, Waldkirch, Germany, Kuopio, Finland, Cardiff, UK, Esch-Belval, Luxembourg; Lung and Particle Research Group, School of Biosciences, Cardiff University, Cardiff, Wales, United Kingdom., Wlodarczyk AJ; HICE-Helmholtz Virtual Institute of Complex Molecular Systems in Environmental Health-Aerosols and Health, www.hice-vi.eu, Neuherberg, Rostock, Munich, Karlsruhe, Berlin, Waldkirch, Germany, Kuopio, Finland, Cardiff, UK, Esch-Belval, Luxembourg; Lung and Particle Research Group, School of Biosciences, Cardiff University, Cardiff, Wales, United Kingdom., Prytherch Z; HICE-Helmholtz Virtual Institute of Complex Molecular Systems in Environmental Health-Aerosols and Health, www.hice-vi.eu, Neuherberg, Rostock, Munich, Karlsruhe, Berlin, Waldkirch, Germany, Kuopio, Finland, Cardiff, UK, Esch-Belval, Luxembourg; Lung and Particle Research Group, School of Biosciences, Cardiff University, Cardiff, Wales, United Kingdom., Michalke B; Research Unit Analytical BioGeoChemistry, Helmholtz Zentrum München-German Research Center for Environmental Health GmbH, Neuherberg, Germany., Krebs T; HICE-Helmholtz Virtual Institute of Complex Molecular Systems in Environmental Health-Aerosols and Health, www.hice-vi.eu, Neuherberg, Rostock, Munich, Karlsruhe, Berlin, Waldkirch, Germany, Kuopio, Finland, Cardiff, UK, Esch-Belval, Luxembourg; Vitrocell GmbH, Waldkirch, Germany., Prévôt AS; Laboratory of Atmospheric Chemistry, Paul Scherrer Institute (PSI), Villigen, Switzerland., Kelbg M; HICE-Helmholtz Virtual Institute of Complex Molecular Systems in Environmental Health-Aerosols and Health, www.hice-vi.eu, Neuherberg, Rostock, Munich, Karlsruhe, Berlin, Waldkirch, Germany, Kuopio, Finland, Cardiff, UK, Esch-Belval, Luxembourg; Institute of Physics, University Rostock, Rostock, Germany., Tiggesbäumker J; HICE-Helmholtz Virtual Institute of Complex Molecular Systems in Environmental Health-Aerosols and Health, www.hice-vi.eu, Neuherberg, Rostock, Munich, Karlsruhe, Berlin, Waldkirch, Germany, Kuopio, Finland, Cardiff, UK, Esch-Belval, Luxembourg; Institute of Physics, University Rostock, Rostock, Germany., Karg E; Joint Mass Spectrometry Centre, CMA-Comprehensive Molecular Analytics, Helmholtz Zentrum München, Neuherberg, Germany., Jakobi G; Joint Mass Spectrometry Centre, CMA-Comprehensive Molecular Analytics, Helmholtz Zentrum München, Neuherberg, Germany., Scholtes S; HICE-Helmholtz Virtual Institute of Complex Molecular Systems in Environmental Health-Aerosols and Health, www.hice-vi.eu, Neuherberg, Rostock, Munich, Karlsruhe, Berlin, Waldkirch, Germany, Kuopio, Finland, Cardiff, UK, Esch-Belval, Luxembourg; Joint Mass Spectrometry Centre, CMA-Comprehensive Molecular Analytics, Helmholtz Zentrum München, Neuherberg, Germany., Schnelle-Kreis J; Joint Mass Spectrometry Centre, CMA-Comprehensive Molecular Analytics, Helmholtz Zentrum München, Neuherberg, Germany., Lintelmann J; Joint Mass Spectrometry Centre, CMA-Comprehensive Molecular Analytics, Helmholtz Zentrum München, Neuherberg, Germany., Matuschek G; Joint Mass Spectrometry Centre, CMA-Comprehensive Molecular Analytics, Helmholtz Zentrum München, Neuherberg, Germany., Sklorz M; Joint Mass Spectrometry Centre, Chair of Analytical Chemistry, Institute of Chemistry, University Rostock, Rostock, Germany., Klingbeil S; HICE-Helmholtz Virtual Institute of Complex Molecular Systems in Environmental Health-Aerosols and Health, www.hice-vi.eu, Neuherberg, Rostock, Munich, Karlsruhe, Berlin, Waldkirch, Germany, Kuopio, Finland, Cardiff, UK, Esch-Belval, Luxembourg; Joint Mass Spectrometry Centre, Chair of Analytical Chemistry, Institute of Chemistry, University Rostock, Rostock, Germany., Orasche J; Joint Mass Spectrometry Centre, CMA-Comprehensive Molecular Analytics, Helmholtz Zentrum München, Neuherberg, Germany., Richthammer P; HICE-Helmholtz Virtual Institute of Complex Molecular Systems in Environmental Health-Aerosols and Health, www.hice-vi.eu, Neuherberg, Rostock, Munich, Karlsruhe, Berlin, Waldkirch, Germany, Kuopio, Finland, Cardiff, UK, Esch-Belval, Luxembourg; Joint Mass Spectrometry Centre, CMA-Comprehensive Molecular Analytics, Helmholtz Zentrum München, Neuherberg, Germany., Müller L; Joint Mass Spectrometry Centre, CMA-Comprehensive Molecular Analytics, Helmholtz Zentrum München, Neuherberg, Germany., Elsasser M; Joint Mass Spectrometry Centre, CMA-Comprehensive Molecular Analytics, Helmholtz Zentrum München, Neuherberg, Germany., Reda A; Joint Mass Spectrometry Centre, CMA-Comprehensive Molecular Analytics, Helmholtz Zentrum München, Neuherberg, Germany., Gröger T; Joint Mass Spectrometry Centre, CMA-Comprehensive Molecular Analytics, Helmholtz Zentrum München, Neuherberg, Germany., Weggler B; HICE-Helmholtz Virtual Institute of Complex Molecular Systems in Environmental Health-Aerosols and Health, www.hice-vi.eu, Neuherberg, Rostock, Munich, Karlsruhe, Berlin, Waldkirch, Germany, Kuopio, Finland, Cardiff, UK, Esch-Belval, Luxembourg; Joint Mass Spectrometry Centre, CMA-Comprehensive Molecular Analytics, Helmholtz Zentrum München, Neuherberg, Germany., Schwemer T; Joint Mass Spectrometry Centre, Chair of Analytical Chemistry, Institute of Chemistry, University Rostock, Rostock, Germany., Czech H; Joint Mass Spectrometry Centre, Chair of Analytical Chemistry, Institute of Chemistry, University Rostock, Rostock, Germany., Rüger CP; Joint Mass Spectrometry Centre, Chair of Analytical Chemistry, Institute of Chemistry, University Rostock, Rostock, Germany., Abbaszade G; Joint Mass Spectrometry Centre, CMA-Comprehensive Molecular Analytics, Helmholtz Zentrum München, Neuherberg, Germany., Radischat C; HICE-Helmholtz Virtual Institute of Complex Molecular Systems in Environmental Health-Aerosols and Health, www.hice-vi.eu, Neuherberg, Rostock, Munich, Karlsruhe, Berlin, Waldkirch, Germany, Kuopio, Finland, Cardiff, UK, Esch-Belval, Luxembourg; Joint Mass Spectrometry Centre, Chair of Analytical Chemistry, Institute of Chemistry, University Rostock, Rostock, Germany., Hiller K; HICE-Helmholtz Virtual Institute of Complex Molecular Systems in Environmental Health-Aerosols and Health, www.hice-vi.eu, Neuherberg, Rostock, Munich, Karlsruhe, Berlin, Waldkirch, Germany, Kuopio, Finland, Cardiff, UK, Esch-Belval, Luxembourg; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, L-4362 Esch-Belval, Luxembourg., Buters JT; HICE-Helmholtz Virtual Institute of Complex Molecular Systems in Environmental Health-Aerosols and Health, www.hice-vi.eu, Neuherberg, Rostock, Munich, Karlsruhe, Berlin, Waldkirch, Germany, Kuopio, Finland, Cardiff, UK, Esch-Belval, Luxembourg; Center of Allergy and Environment (ZAUM), Helmholtz Zentrum München and Technische Universität München, Member of the German Center for Lung Research (DZL), Munich, Germany; CK-CARE, Christine Kühne Center for Allergy Research and Education, Davos, Switzerland., Dittmar G; HICE-Helmholtz Virtual Institute of Complex Molecular Systems in Environmental Health-Aerosols and Health, www.hice-vi.eu, Neuherberg, Rostock, Munich, Karlsruhe, Berlin, Waldkirch, Germany, Kuopio, Finland, Cardiff, UK, Esch-Belval, Luxembourg; Mass Spectrometry Core Unit, Max Delbrück Center for Molecular Medicine Berlin-Buch, Germany., Zimmermann R; HICE-Helmholtz Virtual Institute of Complex Molecular Systems in Environmental Health-Aerosols and Health, www.hice-vi.eu, Neuherberg, Rostock, Munich, Karlsruhe, Berlin, Waldkirch, Germany, Kuopio, Finland, Cardiff, UK, Esch-Belval, Luxembourg; Joint Mass Spectrometry Centre, Chair of Analytical Chemistry, Institute of Chemistry, University Rostock, Rostock, Germany; Joint Mass Spectrometry Centre, CMA-Comprehensive Molecular Analytics, Helmholtz Zentrum München, Neuherberg, Germany.

Publikováno v: PloS one [PLoS One] 2015 Jun 03; Vol. 10 (6), pp. e0126536. Date of Electronic Publication: 2015 Jun 03 (Print Publication: 2015).