Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Prudence P, Lui"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Skin-resident regulatory T cells (Tregs) play an irreplaceable role in orchestrating cutaneous immune homeostasis and repair, including the promotion of hair regeneration via the Notch signaling ligand Jagged-1 (Jag1). While skin Tregs are i
Externí odkaz:
https://doaj.org/article/5216f6881dea4fed8700cc00bf20a4bf
Autor:
Prudence PokWai Lui, Chrysanthi Ainali, Chung-Ching Chu, Manuela Terranova-Barberio, Panagiotis Karagiannis, Angela Tewari, Niloufar Safinia, Ehsan Sharif-Paghaleh, Sophia Tsoka, Grzegorz Woszczek, Paola Di Meglio, Giovanna Lombardi, Antony R. Young, Frank O. Nestle, Niwa Ali
Publikováno v:
iScience, Vol 26, Iss 10, Pp 108029- (2023)
Summary: Skin immune homeostasis is a multi-faceted process where dermal dendritic cells (DDCs) are key in orchestrating responses to environmental stressors. We have previously identified CD141+CD14+ DDCs as a skin-resident immunoregulatory populati
Externí odkaz:
https://doaj.org/article/bfb8903d33a541d1b9febee12c9327fb
Autor:
Clara L. Essmann, Daniel Martinez-Martinez, Rosina Pryor, Kit-Yi Leung, Kalaivani Bala Krishnan, Prudence Pokway Lui, Nicholas D. E. Greene, André E. X. Brown, Vijay M. Pawar, Mandayam A. Srinivasan, Filipe Cabreiro
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
The development of reliable measures of health in ageing organisms is a need in ageing research. Using atomic force microscopy, here, the authors assess whole body stiffness of worms and show that it reflects organismal fitness.
Externí odkaz:
https://doaj.org/article/497f6a1f580e4f1db58b61849bc60df7
Autor:
Emanuel Rognoni, Georgina Goss, Toru Hiratsuka, Kalle H Sipilä, Thomas Kirk, Katharina I Kober, Prudence PokWai Lui, Victoria SK Tsang, Nathan J Hawkshaw, Suzanne M Pilkington, Inchul Cho, Niwa Ali, Lesley E Rhodes, Fiona M Watt
Publikováno v:
eLife, Vol 10 (2021)
Solar ultraviolet radiation (UVR) is a major source of skin damage, resulting in inflammation, premature ageing, and cancer. While several UVR-induced changes, including extracellular matrix reorganisation and epidermal DNA damage, have been document
Externí odkaz:
https://doaj.org/article/4829444af2e143fb9fb4e90ef82c6974
Autor:
Inchul J. Cho, Prudence PokWai Lui, Jana Obajdin, Federica Riccio, Wladislaw Stroukov, Thea Louise Willis, Francesca Spagnoli, Fiona M. Watt
Publikováno v:
Stem Cell Reports, Vol 12, Iss 6, Pp 1190-1200 (2019)
Cellular quiescence is a dormant but reversible cellular state in which cell-cycle entry and proliferation are prevented. Recent studies both in vivo and in vitro demonstrate that quiescence is actively maintained through synergistic interactions bet
Externí odkaz:
https://doaj.org/article/c4c92e1a9ccc43e4b9e63a78512b02c7
Autor:
Timothy A, Scott, Leonor M, Quintaneiro, Povilas, Norvaisas, Prudence P, Lui, Matthew P, Wilson, Kit-Yi, Leung, Lucia, Herrera-Dominguez, Sonia, Sudiwala, Alberto, Pessia, Peter T, Clayton, Kevin, Bryson, Vidya, Velagapudi, Philippa B, Mills, Athanasios, Typas, Nicholas D E, Greene, Filipe, Cabreiro
Publikováno v:
Cell
Summary Fluoropyrimidines are the first-line treatment for colorectal cancer, but their efficacy is highly variable between patients. We queried whether gut microbes, a known source of inter-individual variability, impacted drug efficacy. Combining t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1d2dc8a3b6eba239535c64036cde2bef
https://pubmed.ncbi.nlm.nih.gov/28431245
https://pubmed.ncbi.nlm.nih.gov/28431245