Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Prudence N. Gatt"'
Autor:
David Brown, Prudence N. Gatt, Graeme J. Stewart, Steve Vucic, Fiona C. McKay, Christopher Liddle, Samantha P L Law, Scott N. Byrne, Prue H. Hart, David R. Booth, Stephen D. Schibeci, Grant P Parnell
Publikováno v:
Genes and Immunity
Although genetic and epidemiological evidence indicates vitamin D insufficiency contributes to multiple sclerosis (MS), and serum levels of vitamin D increase on treatment with cholecalciferol, recent metanalyses indicate that this vitamin D form doe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82dcd9079bcb06a7e191eb8c74f83cde
http://europepmc.org/articles/PMC8387232
http://europepmc.org/articles/PMC8387232
Autor:
Clara P. Manrique, Fiona C. McKay, Prudence N. Gatt, Steve Vucic, Graeme J. Stewart, Nicole Fewings, Therese Burke, Monica A. I. Basuki, David R. Booth, Stephen D. Schibeci, Allan G. Kermode, Marzena J. Fabis-Pedrini, Dorothee Nickles, Anita Goldinger, Grant P Parnell, J. Edwards, Sergio E. Baranzini, Jacob L. McCauley
Publikováno v:
Journal of Autoimmunity. 78:57-69
Multiple Sclerosis (MS) is a neurological condition driven in part by immune cells from the peripheral circulation, the targets for current successful therapies. The autoimmune and MS risk gene ZMIZ1 is underexpressed in blood in people with MS. We s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3d207a717d20aee67fd6ed09cc9e6b7
https://doi.org/10.1016/j.jaut.2016.12.006
https://doi.org/10.1016/j.jaut.2016.12.006
Autor:
Prudence N. Gatt, Sergio E. Baranzini, Allan G. Kermode, Jacob L. McCauley, Fiona C. McKay, Nicole Fewings, David R. Booth, Dorothee Nickles, Stephen D. Schibeci, Graeme J. Stewart, Clara P. Manrique, Therese Burke, Anita Goldinger, J. Edwards, Steve Vucic, Grant P Parnell, Marzena J. Fabis-Pedrini, Monica A. I. Basuki
Publikováno v:
Data in Brief
Data in Brief, Vol 11, Iss C, Pp 364-370 (2017)
Data in Brief, Vol 11, Iss C, Pp 364-370 (2017)
The data presented in this article are related to the research article entitled “The autoimmune risk gene ZMIZ1 is a vitamin D responsived marker of a molecular phenotype of multiple sclerosis” Fewings et al. (2017) [1]. Here we identify the set
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::396e98c7a555aef04d4fb95489199858
http://europepmc.org/articles/PMC5329066
http://europepmc.org/articles/PMC5329066
Autor:
Vilija Jokubaitis, Manuel Comabella, Vittorio Martinelli, Fiona C. McKay, Filippo Martinelli Boneschi, Malgorzata Krupa, Giuseppe Liberatore, Jeannette Lechner-Scott, Vijayaprakash Suppiah, G. Comi, Mark Slee, Allan G. Kermode, Xavier Montalban, C King, Max Moldovan, Bruce V. Taylor, Melissa Sorosina, Marzena J. Fabis-Pedrini, Sunny Malhotra, Sunil Mahurkar, Ferdinando Clarelli, Koen Vandenbroeck, Prudence N. Gatt, Alfredo Antigüedad
Publikováno v:
The Pharmacogenomics Journal. 17:312-318
Up to 50% of multiple sclerosis (MS) patients do not respond to interferon-beta (IFN-β) treatment and determination of response requires lengthy clinical follow-up of up to 2 years. Response predictive genetic markers would significantly improve dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f28febae3448634598bc0ad7e307c66f
https://doi.org/10.1038/tpj.2016.20
https://doi.org/10.1038/tpj.2016.20
Autor:
Dorothee Nickles, Prudence N. Gatt, Steve Vucic, Michael Barnett, Mark Slee, David R. Booth, Stephen D. Schibeci, Malgorzata Krupa, Graeme J. Stewart, Sergio E. Baranzini, Grant P Parnell, Andrew P.D. Henderson, Fiona C. McKay, Marcel Batten
Publikováno v:
Clinical Immunology. 151(1):16-24
We have identified a marked over-representation of transcription factors controlling differentiation of T, B, myeloid and NK cells among the 110 MS genes now known to be associated with multiple sclerosis (MS). To test if the expression of these gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbf1b9c569d0cf44ca55d6a401d96548
Autor:
Mark Slee, Christopher Liddle, Steve Vucic, Fiona C. McKay, Jeannette Lechner-Scott, Malgorzata Krupa, Grant W. Montgomery, Grant P Parnell, Prudence N. Gatt, Simon Broadley, Joseph E. Powell, Graeme J. Stewart, Peter M. Visscher, David R. Booth, Stephen D. Schibeci
Publikováno v:
Multiple Sclerosis Journal. 20:675-685
Background: Multiple Sclerosis (MS) is an immune-mediated disease of the central nervous system which responds to therapies targeting circulating immune cells. Objective: Our aim was to test if the T-cell activation gene expression pattern (TCAGE) we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::609f62a599e39fb0c2a08de0d2921787
https://doi.org/10.1177/1352458513507819
https://doi.org/10.1177/1352458513507819
Autor:
Prudence N. Gatt, Ann M. Simpson, Zeger Debyser, Rik Gijsbers, Ming Q. Wei, Michelle R. Byrne, M. Anne Swan, Bronwyn A. O'Brien, Najah T. Nassif, Edwin Ch'ng, Binhai Ren
Publikováno v:
The Journal of Gene Medicine. 15:28-41
Background Type 1 diabetes (T1D) results from an autoimmune attack against the insulin-producing b-cells of the pancreas. The present study aimed to reverse T1D by gene therapy. Methods We used a novel surgical technique, which involves isolating the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab555d91db3c67774722d17c96a14175
https://doi.org/10.1002/jgm.2692
https://doi.org/10.1002/jgm.2692
Autor:
Therese Burke, Prudence N. Gatt, Monica A. I. Basuki, Steve Vucic, Fiona C. McKay, Allan G. Kermode, Nicole Fewings, Anita Goldinger, Marzena J. Fabis-Pedrini, Graeme J. Stewart, Joseph E. Powell, David R. Booth, Stephen D. Schibeci, Grant P Parnell
Publikováno v:
Clinical immunology (Orlando, Fla.). 163
Multiple Sclerosis (MS) is an autoimmune disease treated by therapies targeting peripheral blood cells. We previously identified that expression of two MS-risk genes, the transcription factors EOMES and TBX21 (ET), was low in blood from MS and stable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::626cdab1064f3f004648d13d6f01c812
https://pubmed.ncbi.nlm.nih.gov/26762769
https://pubmed.ncbi.nlm.nih.gov/26762769
Autor:
Prudence N. Gatt, David R. Booth, Edwin Hoe, Stephen D. Schibeci, Grant P Parnell, Graeme J. Stewart, Fiona C. McKay
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 10, p e77508 (2013)
PLoS ONE, Vol 8, Iss 10, p e77508 (2013)
The IL7Rα gene is unequivocally associated with susceptibility to multiple sclerosis (MS). Haplotype 2 (Hap 2) confers protection from MS, and T cells and dendritic cells (DCs) of Hap 2 exhibit reduced splicing of exon 6, resulting in production of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8682e1cf108115dcbab58f8386ad8b6e
https://pubmed.ncbi.nlm.nih.gov/24147013
https://pubmed.ncbi.nlm.nih.gov/24147013
Autor:
Con Yiannikas, Fabienne Brilot, Andrew Bleasel, Victor S.C. Fung, Prudence N. Gatt, John Parratt, Graeme J. Stewart, Russell C. Dale, Vera Merheb, David R. Booth, Stephen W. Reddel, Michael Barnett, Steve Vucic, Sudarshini Ramanathan, Mahtab Ghadiri, Andrew P.D. Henderson
Publikováno v:
Journal of Clinical Neuroscience. 21:2035
Autoantibodies such as those targeting aquaporin-4 are important biomarkers in central nervous system demyelination. We examined a cohort of patients with aquaporin-4 antibody seronegative neuromyelitis optica spectrum disorder (NMOSD) for serum anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22af72638d22c69bec9d6298fa172f5c
https://doi.org/10.1016/j.jocn.2014.06.021
https://doi.org/10.1016/j.jocn.2014.06.021