Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Prudence Donovan"'
Autor:
Prudence Donovan, Jatin Patel, James Dight, Ho Yi Wong, Seen-Ling Sim, Valentine Murigneux, Mathias Francois, Kiarash Khosrotehrani
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
The contribution of endothelial progenitor cells to tumor angiogenesis is controversial. Here, the authors trace the lineage differentiation of endovascular progenitor cells and demonstrate their functional importance in tumor vascularization and pro
Externí odkaz:
https://doaj.org/article/b472c48355de4681b6ea5ebc4841da96
Autor:
Pierpaolo Ginefra, Bruno G.H. Filippi, Prudence Donovan, Sylvain Bessonnard, Daniel B. Constam
Publikováno v:
Cell Reports, Vol 22, Iss 8, Pp 2176-2189 (2018)
Summary: Furin trafficking, and that of related proprotein convertases (PCs), may regulate which substrates are accessible for endoproteolysis, but tools to directly test this hypothesis have been lacking. Here, we develop targeted biosensors that in
Externí odkaz:
https://doaj.org/article/0a11b83a8aa346d683afe0d23d5524e1
Autor:
Seen-Ling Sim, Mathias Francois, Prudence Donovan, Jatin Patel, Kiarash Khosrotehrani, Ho Yi Wong, James Dight, Valentine Murigneux
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Tumor vascularization is a hallmark of cancer central to disease progression and metastasis. Current anti-angiogenic therapies have limited success prompting the need to better understand the cellular origin of tumor vessels. Using fate-mapping analy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93b90c33e8f30cbc52c41678ba05b8f1
https://doaj.org/article/b472c48355de4681b6ea5ebc4841da96
https://doaj.org/article/b472c48355de4681b6ea5ebc4841da96
Autor:
Ho Yi Wong, Kiarash Khosrotehrani, Jatin Patel, Abbas Shafiee, Nicholas M. Fisk, Dietmar W. Hutmacher, Prudence Donovan
Publikováno v:
The FASEB Journal. 31:610-624
The prospect of using endothelial progenitors is currently hampered by their low engraftment upon transplantation. We report that mesenchymal stem/stromal cells (MSCs), independent of source and age, improve the engraftment of endothelial colony form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e8e367085639b59c715c5e8d5f126dd
https://doi.org/10.1096/fj.201600937
https://doi.org/10.1096/fj.201600937
Autor:
Bruno G.H. Filippi, Pierpaolo Ginefra, Sylvain Bessonnard, Prudence Donovan, Daniel B. Constam
Publikováno v:
Cell Reports, Vol 22, Iss 8, Pp 2176-2189 (2018)
Summary Furin trafficking, and that of related proprotein convertases (PCs), may regulate which substrates are accessible for endoproteolysis, but tools to directly test this hypothesis have been lacking. Here, we develop targeted biosensors that ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a0b1adce3ae275d380ef093d7668c91
https://pubmed.ncbi.nlm.nih.gov/29466742
https://pubmed.ncbi.nlm.nih.gov/29466742
Autor:
Prudence Donovan, Katherine W Rogers, Katja Muehlethaler, Olivier A. Dubey, Patrick Müller, Donata Rimoldi, Daniel B. Constam, Susanna Kallioinen
The secreted growth factor Activin-A of the TGFβ family and its receptors can promote or inhibit several cancer hallmarks including tumor cell proliferation and differentiation, vascularization, lymphangiogenesis and inflammation. However, a role in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5982812714ecd2266ce598a2a197f74
https://doi.org/10.1101/144857
https://doi.org/10.1101/144857
Autor:
Nicholas M. Fisk, Prudence Donovan, Ho Yi Wong, Jatin Patel, Mathias Francois, Kiarash Khosrotehrani, Elke Seppanen, Mathieu P Rodero
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 37
Background: The formation of new blood vessels during adult life is often explained by angiogenesis. However, an alternate proposal now suggests that neo-vessels form from endothelial progenitors able to assemble all the intimal layers of vessel stru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21083804222a55cc51e95863894171c5
https://doi.org/10.1161/atvb.37.suppl_1.6
https://doi.org/10.1161/atvb.37.suppl_1.6
Publikováno v:
Stem cells translational medicine. 5(10)
Since the discovery of endothelial progenitor cells (EPCs) almost 2 decades ago, there has been great hope in their use in treating chronic ischemic disease. Unfortunately, to date, many of the clinical trials using EPCs have been hampered by the lac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e2bc1cb8d530847372f35c639bee72c
https://pubmed.ncbi.nlm.nih.gov/27381992
https://pubmed.ncbi.nlm.nih.gov/27381992
Publikováno v:
Oncotarget
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba917f7cba3f6d2e3d77817f039d7c36
https://doi.org/10.18632/oncotarget.21389
https://doi.org/10.18632/oncotarget.21389
Publikováno v:
Journal of Investigative Dermatology. 138:S210
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6edb43292dcf82f83a7387564eb96222
https://doi.org/10.1016/j.jid.2018.03.1255
https://doi.org/10.1016/j.jid.2018.03.1255