Zobrazeno 1 - 10
of 310
pro vyhledávání: '"Prp8"'
Publikováno v:
Acta Biochimica et Biophysica Sinica, Vol 55, Pp 1310-1318 (2023)
Intein-mediated protein splicing has been widely used in protein engineering; however, the splicing efficiency and extein specificity usually limit its further application. Thus, there is a demand for more general inteins that can overcome these limi
Externí odkaz:
https://doaj.org/article/43da6aee4ede4527af47a561d51ab8fb
Akademický článek
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Publikováno v:
Cells, Vol 11, Iss 21, p 3460 (2022)
Background: Multiple organ dysfunction syndrome (MODS) occurs in the gastrointestinal tract and injured intestinal mucosa is the anatomical basis for various diseases. The expression of circular RNAs (circRNAs) is implicated in many diseases; however
Externí odkaz:
https://doaj.org/article/399cff0a65894e718d114bf96f634e89
Autor:
Zhong Li, Bin Fu, Cathleen M. Green, Binbin Liu, Jing Zhang, Yuekun Lang, Sudha Chaturvedi, Marlene Belfort, Guojian Liao, Hongmin Li
Publikováno v:
Emerging Microbes and Infections, Vol 8, Iss 1, Pp 895-908 (2019)
ABSTRACTThe Prp8 intein is one of the most widespread eukaryotic inteins, present in important pathogenic fungi, including Cryptococcus and Aspergillus species. Because the processed Prp8 carries out essential and non-redundant cellular functions, a
Externí odkaz:
https://doaj.org/article/8083ea2850c44e5392a0f6ca9df816df
Autor:
José Alex Lourenço Fernandes, Matheus da Silva Zatti, Thales Domingos Arantes, Maria Fernanda Bezerra de Souza, Mariana Marchi Santoni, Danuza Rossi, Cleslei Fernando Zanelli, Xiang-Qin Liu, Eduardo Bagagli, Raquel Cordeiro Theodoro
Publikováno v:
Journal of Fungi, Vol 8, Iss 8, p 846 (2022)
Inteins are genetic mobile elements that are inserted within protein-coding genes, which are usually housekeeping genes. They are transcribed and translated along with the host gene, then catalyze their own splicing out of the host protein, which ass
Externí odkaz:
https://doaj.org/article/39aa3f9e192d4ec4a644d451fca174e1
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 6 (2020)
Retinitis pigmentosa (RP) represents genetically heterogeneous and clinically variable disease characterized by progressive degeneration of photoreceptors resulting in a gradual loss of vision. The autosomal dominant RP type 13 (RP13) has been linked
Externí odkaz:
https://doaj.org/article/4f11d4c3f57a478d8510b3f294da03ce
Autor:
Mayerle, Megan, Raghavan, Madhura, Ledoux, Sarah, Price, Argenta, Stepankiw, Nicholas, Hadjivassiliou, Haralambos, Moehle, Erica A., Mendoza, Senén D., Pleiss, Jeffrey A., Guthrie, Christine, Abelson, John
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2017 May 01. 114(18), 4739-4744.
Externí odkaz:
https://www.jstor.org/stable/26481867
Autor:
Abelson, John
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2017 Apr . 114(17), 4288-4293.
Externí odkaz:
https://www.jstor.org/stable/26480733
Akademický článek
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Autor:
Marco Preußner, Junqiao Jia, Markus C. Wahl, Bernhard Loll, Florian Heyd, Eva Absmeier, Claudia Alings, Oleg M. Ganichkin
Publikováno v:
Nucleic Acids Research
The single G protein of the spliceosome, Snu114, has been proposed to facilitate splicing as a molecular motor or as a regulatory G protein. However, available structures of spliceosomal complexes show Snu114 in the same GTP-bound state, and presentl