Zobrazeno 1 - 10
of 899
pro vyhledávání: '"Proximity labeling"'
Autor:
Xiaofang Zhong, Qiongyu Li, Benjamin J Polacco, Trupti Patil, Aaron Marley, Helene Foussard, Prachi Khare, Rasika Vartak, Jiewei Xu, Jeffrey F DiBerto, Bryan L Roth, Manon Eckhardt, Mark von Zastrow, Nevan J Krogan, Ruth Hüttenhain
Publikováno v:
Molecular Systems Biology, Vol 20, Iss 8, Pp 952-971 (2024)
Abstract Proximity labeling (PL) via biotinylation coupled with mass spectrometry (MS) captures spatial proteomes in cells. Large-scale processing requires a workflow minimizing hands-on time and enhancing quantitative reproducibility. We introduced
Externí odkaz:
https://doaj.org/article/b1fa4dc8556644079c79cd440ac3a387
Publikováno v:
In Molecular & Cellular Proteomics January 2025 24(1)
Publikováno v:
Frontiers in Plant Science, Vol 15 (2024)
The phenylpropanoid pathway is one of the main carbon sinks in plants, channeling phenylalanine towards thousands of products including monolignols, stilbenes, flavonoids and volatile compounds. The enzymatic steps involved in many of these pathways
Externí odkaz:
https://doaj.org/article/2c6781dcc2ec4b2d8dbad5fbbac91f8a
Autor:
Jenai Quan, Qing Fan, Lacy M. Simons, Samuel N. Smukowski, Caitlin Pegg, Richard Longnecker, Jeffrey N. Savas, Judd F. Hultquist, Gregory A. Smith
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
ABSTRACT Neurotropic alphaherpesviruses, including herpes simplex virus type 1 and pseudorabies virus, establish a lifelong presence within the peripheral nervous system of their mammalian hosts. Upon entering cells, two conserved tegument proteins,
Externí odkaz:
https://doaj.org/article/c8acdaec5a534af7842134a5fb8c975a
Autor:
Liu, Jinmin 1, 2, Kulkarni, Amogh 2, 3, Gao, Yong-Qi 2, Urul, Daniel A. 2, 4, Hamelin, Romain 2, Novotny, Balázs Á. 2, Long, Marcus J.C. 5, ∗, Aye, Yimon 1, 2, 6, ∗∗
Publikováno v:
In Cell 26 December 2024 187(26):7450-7469
Autor:
Junji Ren, Zibin Zhang, Shuo Geng, Yuxi Cheng, Huize Han, Zhipu Fan, Wenbing Dai, Hua Zhang, Xueqing Wang, Qiang Zhang, Bing He
Publikováno v:
Nano-Micro Letters, Vol 16, Iss 1, Pp 1-24 (2024)
Highlights Novel enzyme-induced proximity labeling technology in nanoparticles (nano-EPL). Nano-EPL enables dynamic molecular mapping of the intracellular delivery of nanoparticles in macrophages. Nano-EPL enables the elucidation of a comprehensive p
Externí odkaz:
https://doaj.org/article/020061f4190f4fb0aabdd85b334a31b8
Autor:
Marie Schöl, Rebekka Schempp, Thomas Hennig, Dominik Wigger, Fabian Schumacher, Burkhard Kleuser, Christian Stigloher, Marco van Ham, Lothar Jänsch, Sibylle Schneider-Schaulies, Lars Dölken, Elita Avota
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Ceramides generated by the activity of the neutral sphingomyelinase 2 (nSMase2) play a pivotal role in stress responses in mammalian cells. Dysregulation of sphingolipid metabolism has been implicated in numerous inflammation-related pathologies. How
Externí odkaz:
https://doaj.org/article/41085d444af749728f9be4c34902f5ed
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Virus receptors determine the tissue tropism of viruses and have a certain relationship with the clinical outcomes caused by viral infection, which is of great importance for the identification of virus receptors to understand the infection mechanism
Externí odkaz:
https://doaj.org/article/455a1f4ddfbd4660a60d3815330d54f8
Publikováno v:
In Cell Chemical Biology 20 June 2024 31(6):1118-1131
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-22 (2023)
Abstract Protein‒protein, protein‒RNA, and protein‒DNA interaction networks form the basis of cellular regulation and signal transduction, making it crucial to explore these interaction networks to understand complex biological processes. Tradi
Externí odkaz:
https://doaj.org/article/799bf1f5074c4df399069d6cf42c7240