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In vivo spectroscopic imaging and localized spectroscopy by 1H nuclear magnetic resonance. Application to the study of tumor physiopathology by mapping of metabolites and extracellular pH in the C6 cell glioma model

Autor: Provent, Peggy

Publikováno v: Biophysique [physics.bio-ph]. Université Joseph-Fourier-Grenoble I, 2006. Français
Biophysique [physics.bio-ph]. Université Joseph-Fourier-Grenoble I, 2006. Français. ⟨NNT : ⟩

The aim of this work was to optimize the conditions and the acquisition techniques for spectroscopy and spectroscopic imaging by 1H NMR in vivo in small animals and to apply these techniques to two biological topics. Acquisition conditions have been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e983ec4d5d903c2cfd5e91c458443213
https://tel.archives-ouvertes.fr/tel-00134012

Assessment of multiparametric MRI in a human glioma model to monitor cytotoxic and anti-angiogenic drug effects

Autor: Lemasson, Benjamin, Christen, Thomas, Tizon, Xavier, Farion, Régine, Fondraz, Nadège, Provent, Peggy, Segebarth, Christoph, Barbier, Emmanuel, Genne, Philippe, Duchamp, Olivier, Remy, Chantal

Publikováno v: NMR in Biomedicine
NMR in Biomedicine, Wiley, 2011, 24 (5), pp.473-82. ⟨10.1002/nbm.1611⟩

International audience; Early imaging or blood biomarkers of tumor response is needed to customize anti-tumor therapy on an individual basis. This study evaluates the sensitivity and relevance of five potential MRI biomarkers. Sixty nude rats were im

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______212::806f694342882fe9c58de36688f75bd9
https://www.hal.inserm.fr/inserm-00607949

Blood-brain barrier permeability to manganese and to Gd-DOTA in a rat model of transient cerebral ischaemia

Autor: Grillon, Emmanuelle, Provent, Peggy, Montigon, Olivier, Segebarth, Christoph, Rémy, Chantal, Barbier, Emmanuel

Publikováno v: NMR in Biomedicine
NMR in Biomedicine, Wiley, 2008, 21 (5), pp.427-36. ⟨10.1002/nbm.1206⟩

International audience; Loss of integrity of the blood-brain barrier (BBB) and brain swelling is a potentially lethal complication of reperfusion in human stroke. To assess the time course of BBB modifications, we performed angiography, diffusion-wei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1398::eb80aca0a32048c5bcee7eed528521fc
https://www.hal.inserm.fr/inserm-00381344/document