Epithelial-mesenchymal transition sensitizes breast cancer cells to cell death via the fungus-derived sesterterpenoid ophiobolin A

Autor: Keighley N. Reisenauer, Yongfeng Tao, Provas Das, Shuxuan Song, Haleigh Svatek, Saawan D. Patel, Sheridan Mikhail, Alec Ingros, Peter Sheesley, Marco Masi, Angela Boari, Antonio Evidente, Alexander Kornienko, Daniel Romo, Joseph Taube

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)

Abstract The epithelial–mesenchymal transition (EMT) imparts properties of cancer stem-like cells, including resistance to frequently used chemotherapies, necessitating the identification of molecules that induce cell death specifically in stem-lik

Externí odkaz: https://doaj.org/article/d75b28ec027d450f93ccf40375922980

Epithelial-mesenchymal transition sensitizes breast cancer cells to cell death via the fungus-derived sesterterpenoid ophiobolin A

Autor: Saawan D. Patel, Shuxuan Song, Provas Das, Alec Ingros, Sheridan Mikhail, Haleigh Svatek, Angela Boari, Peter Sheesley, Antonio Evidente, Yongfeng Tao, Alexander Kornienko, Marco Masi, Daniel Romo, Joseph H. Taube, Keighley N. Reisenauer

Publikováno v: Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific reports (Nature Publishing Group) 11 (2021). doi:10.1038/s41598-021-89923-9
info:cnr-pdr/source/autori:Reisenauer K.N.; Tao Y.; Das P.; Song S.; Svatek H.; Patel S.D.; Mikhail S.; Ingros A.; Sheesley P.; Masi M.; Boari A.; Evidente A.; Kornienko A.; Romo D.; Taube J./titolo:Epithelial-mesenchymal transition sensitizes breast cancer cells to cell death via the fungus-derived sesterterpenoid ophiobolin A/doi:10.1038%2Fs41598-021-89923-9/rivista:Scientific reports (Nature Publishing Group)/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume:11

The epithelial–mesenchymal transition (EMT) imparts properties of cancer stem-like cells, including resistance to frequently used chemotherapies, necessitating the identification of molecules that induce cell death specifically in stem-like cells w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1adf6704b3fcf98aae52c6abe4d41d13
http://europepmc.org/articles/PMC8137940

Abstract PS16-07: Blocking H3K27me3 methyltransferase or demethylase activity impacts epithelial-mesenchymal plasticity, suppressing tumor growth and metastasis

Autor: Lacey E. Dobrolecki, John D. Landua, Provas Das, Joseph H. Taube, Kelsey S. Johnson, Michael T. Lewis

Publikováno v: Cancer Research. 81:PS16-07

Background: Epithelial-mesenchymal plasticity (EMP) is key feature driving breast cancer metastasis. Induction of epithelial-mesenchymal transition (EMT) increases the migratory and invasive capabilities associated with metastatic competence and endo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2d83da0f44a9960e6b818a421b4d8de8
https://doi.org/10.1158/1538-7445.sabcs20-ps16-07

of Molecular association of glucose-6-phosphate isomerase and pyruvate kinase M2 with glyceraldehyde-3-phosphate dehydrogenase in cancer cells

Autor: Das, Mahua, Bag, Arup, Saha, Shekhar, Ghosh, Alok, Dey, Sumit, Provas Das, Mandal, Chitra, Subhankar Ray, Saikat Chakrabarti, Ray, Manju, Siddhartha Jana

of Molecular association of glucose-6-phosphate isomerase and pyruvate kinase M2 with glyceraldehyde-3-phosphate dehydrogenase in cancer cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eaba3f75a1241c7d8ca52ca294a1ac4

Regulation of nonmuscle myosin II during 3-methylcholanthrene induced dedifferentiation of C2C12 myotubes

Autor: Provas Das, Mahua Rani Das, Siddhartha S. Jana, Shekhar Saha, Sumit K. Dey

Publikováno v: Experimental Cell Research. 326:68-77

3-Methylcholanthrene (3MC) induces tumor formation at the site of injection in the hind leg of mice within 110 days. Recent reports reveal that the transformation of normal muscle cells to atypical cells is one of the causes for tumor formation, howe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac7203d55a24089a7bf69018a31468cb
https://doi.org/10.1016/j.yexcr.2014.05.015