A single-cysteine mutant and chimeras of essential Leishmania Erv can complement the loss of Erv1 but not of Mia40 in yeast

Autor: Kai Hell, Linda Liedgens, Alexandra Stiegler, Margarida Duarte, Maike Eberhardt, Marcel Deponte, Ulrike Wirth, Sandra Specht, Ana M. Tomás

Publikováno v: Redox Biology, Vol 15, Iss C, Pp 363-374 (2018)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Redox Biology

Mia40/CHCHD4 and Erv1/ALR are essential for oxidative protein folding in the mitochondrial intermembrane space of yeast and mammals. In contrast, many protists, including important apicomplexan and kinetoplastid parasites, lack Mia40. Furthermore, th

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http://www.sciencedirect.com/science/article/pii/S2213231717306456