Oral minimal model-based estimates of insulin sensitivity in obese youth depend on oral glucose tolerance test protocol duration

Autor: Kai Bartlette, Anne-Marie Carreau, Danielle Xie, Yesenia Garcia-Reyes, Haseeb Rahat, Laura Pyle, Kristen J. Nadeau, Melanie Cree-Green, Cecilia Diniz Behn

Publikováno v: Metabolism Open, Vol 9, Iss , Pp 100078- (2021)

Introduction: The Oral Minimal Model (OMM), a differential-equations based mathematical model of glucose-insulin dynamics, utilizes data from a frequently sampled oral glucose tolerance test (OGTT) to quantify insulin sensitivity (SI). OMM-based esti

Externí odkaz: https://doaj.org/article/89ba0fb90e574896b7e0997a1a945202

Analyses of protein cores reveal fundamental differences between solution and crystal structures

Autor: Zhe Mei, Alex T. Grigas, Corey S. O'Hern, Zachary A. Levine, Lynne Regan, John D. Treado

Publikováno v: Mei, Z, Treado, J D, Grigas, A T, Levine, Z A, Regan, L & O'hern, C S 2020, ' Analyses of protein cores reveal fundamental differences between solution and crystal structures ', Proteins: Structure, Function, and Bioinformatics, vol. 88, no. 9 . https://doi.org/10.1002/prot.25884
Proteins

There have been several studies suggesting that protein structures solved by NMR spectroscopy and x-ray crystallography show significant differences. To understand the origin of these differences, we assembled a database of high-quality protein struc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8904ca120a5062574e2a4eb3f0df197
https://www.pure.ed.ac.uk/ws/files/137623155/Mei_et_al_2020_Proteins_Structure_Function_and_Bioinformatics.pdf

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Oral minimal model-based estimates of insulin sensitivity in obese youth depend on oral glucose tolerance test protocol duration.

Autor: Bartlette K; Department of Applied Mathematics and Statistics, Colorado School of Mines, Golden, CO, 80401, USA., Carreau AM; Division of Endocrinology, Department of Pediatrics, University of Colorado Denver Anschutz Medical Campus, Aurora, CO, 80045, USA., Xie D; Division of Endocrinology, Department of Pediatrics, University of Colorado Denver Anschutz Medical Campus, Aurora, CO, 80045, USA., Garcia-Reyes Y; Division of Endocrinology, Department of Pediatrics, University of Colorado Denver Anschutz Medical Campus, Aurora, CO, 80045, USA., Rahat H; Division of Endocrinology, Department of Pediatrics, University of Colorado Denver Anschutz Medical Campus, Aurora, CO, 80045, USA., Pyle L; Department of Pediatrics, University of Colorado Denver Anschutz Medical Campus, Aurora, CO, 80045, USA.; Department of Biostatics and Informatics, Colorado School of Public Health, Aurora, CO, 80045, USA., Nadeau KJ; Division of Endocrinology, Department of Pediatrics, University of Colorado Denver Anschutz Medical Campus, Aurora, CO, 80045, USA.; Center for Women's Health Research, Aurora, CO, USA., Cree-Green M; Division of Endocrinology, Department of Pediatrics, University of Colorado Denver Anschutz Medical Campus, Aurora, CO, 80045, USA.; Department of Biostatics and Informatics, Colorado School of Public Health, Aurora, CO, 80045, USA., Diniz Behn C; Department of Applied Mathematics and Statistics, Colorado School of Mines, Golden, CO, 80401, USA.; Division of Endocrinology, Department of Pediatrics, University of Colorado Denver Anschutz Medical Campus, Aurora, CO, 80045, USA.

Publikováno v: Metabolism open [Metabol Open] 2021 Jan 07; Vol. 9, pp. 100078. Date of Electronic Publication: 2021 Jan 07 (Print Publication: 2021).