Cannabinoid receptor CB1 regulates STAT3 activity and its expression dictates the responsiveness to SR141716 treatment in human glioma patients' cells

Autor: Ciaglia E1, 2, Torelli G3, 4, Pisanti S1, Picardi P1, D'Alessandro A2, Laezza C5, 6, Malfitano AM1, Fiore D2, Pagano Zottola AC2, Proto MC2, Catapano G3, Gazzerro P2, Bifulco M1

Publikováno v: Oncotarget (2015).
info:cnr-pdr/source/autori:Ciaglia E1,2, Torelli G3,4, Pisanti S1,2, Picardi P1,2, D'Alessandro A2, Laezza C5,6, Malfitano AM1,2, Fiore D2, Pagano Zottola AC2, Proto MC2, Catapano G3, Gazzerro P2, Bifulco M1,2./titolo:Cannabinoid receptor CB1 regulates STAT3 activity and its expression dictates the responsiveness to SR141716 treatment in human glioma patients' cells./doi:/rivista:Oncotarget/anno:2015/pagina_da:/pagina_a:/intervallo_pagine:/volume

Herein we show that a majority of human brain tumor samples and cell lines over-expressed cannabinoid receptor CB1 as compared to normal human astrocytes (NHA), while uniformly expressed low levels of CB2. This finding prompted us to investigate the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::bd26161855b01bdfb903c4fc956bd5f3
https://publications.cnr.it/doc/331491