Zobrazeno 1 - 10
of 954
pro vyhledávání: '"Proteome profiling"'
Autor:
Mira L Burtscher, Stephan Gade, Martin Garrido-Rodriguez, Anna Rutkowska, Thilo Werner, H Christian Eberl, Massimo Petretich, Natascha Knopf, Katharina Zirngibl, Paola Grandi, Giovanna Bergamini, Marcus Bantscheff, Maria Fälth-Savitski, Julio Saez-Rodriguez
Publikováno v:
Molecular Systems Biology, Vol 20, Iss 4, Pp 458-474 (2024)
Abstract Complex disease phenotypes often span multiple molecular processes. Functional characterization of these processes can shed light on disease mechanisms and drug effects. Thermal Proteome Profiling (TPP) is a mass-spectrometry (MS) based tech
Externí odkaz:
https://doaj.org/article/6a429efa9e5f4ec6975418af5d3be112
Autor:
Harrison T. Shanley, Aya C. Taki, Nghi Nguyen, Tao Wang, Joseph J. Byrne, Ching-Seng Ang, Michael G. Leeming, Nicholas Williamson, Bill C.H. Chang, Abdul Jabbar, Brad E. Sleebs, Robin B. Gasser
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 25, Iss , Pp 100534- (2024)
Infections and diseases caused by parasitic nematodes have a major adverse impact on the health and productivity of animals and humans worldwide. The control of these parasites often relies heavily on the treatment with commercially available chemica
Externí odkaz:
https://doaj.org/article/e3738831bebf4b19be4951ffbbc3215f
Autor:
Harrison T. Shanley, Aya C. Taki, Nghi Nguyen, Tao Wang, Joseph J. Byrne, Ching-Seng Ang, Michael G. Leeming, Shuai Nie, Nicholas Williamson, Yuanting Zheng, Neil D. Young, Pasi K. Korhonen, Andreas Hofmann, Bill C.H. Chang, Tim N.C. Wells, Cécile Häberli, Jennifer Keiser, Abdul Jabbar, Brad E. Sleebs, Robin B. Gasser
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 24, Iss , Pp 100522- (2024)
Within the context of our anthelmintic discovery program, we recently identified and evaluated a quinoline derivative, called ABX464 or obefazimod, as a nematocidal candidate; synthesised a series of analogues which were assessed for activity against
Externí odkaz:
https://doaj.org/article/bd1202bcf63a4ff0ade2f378a914072b
Autor:
Jin Zhang, Cong Lin, Sha Jin, Hongshuang Wang, Yibo Wang, Xiubo Du, Mark R. Hutchinson, Huiying Zhao, Le Fang, Xiaohui Wang
Publikováno v:
Exploration, Vol 3, Iss 5, Pp n/a-n/a (2023)
Abstract In recent years, cannabidiol (CBD), a non‐psychotropic cannabinoid, has garnered substantial interest in drug development due to its broad pharmacological activity and multi‐target effects. Diabetes is a chronic metabolic disease that ca
Externí odkaz:
https://doaj.org/article/c2ffb01d93ab4682b070c966a5a7deb4
Akademický článek
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Autor:
Raffaella Lazzarini, Maria Eléxpuru-Zabaleta, Francesco Piva, Matteo Giulietti, Gianluca Fulgenzi, Maria Fiorella Tartaglione, Laura Zingaretti, Adriano Tagliabracci, Matteo Valentino, Lory Santarelli, Massimo Bracci
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 253, Iss , Pp 114650- (2023)
Extremely low-frequency electromagnetic fields (ELF-MF) can modify the cell viability and regulatory processes of some cell types, including breast cancer cells. Breast cancer is a multifactorial disease where a role for ELF-MF cannot be excluded. EL
Externí odkaz:
https://doaj.org/article/44a186460022496aaa6691b3d271e9c3
Autor:
Yueting Xiong, Yongtao Zheng, Yan Yan, Jun Yao, Hebin Liu, Fenglin Shen, Siyuan Kong, Shuang Yang, Guoquan Yan, Huanhuan Zhao, Xinwen Zhou, Jia Hu, Bin Zhou, Tao Jin, Huali Shen, Bing Leng, Pengyuan Yang, Xiaohui Liu
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 2, Pp 1-14 (2022)
Abstract The prevalence of intracranial aneurysm (IA) is increasing, and the consequences of its rupture are severe. This study aimed to reveal specific, sensitive, and non‐invasive biomarkers for diagnosis and classification of ruptured and unrupt
Externí odkaz:
https://doaj.org/article/f042292c61d0428fad0e65913517f278
Autor:
Aya C. Taki, Tao Wang, Nghi N. Nguyen, Ching-Seng Ang, Michael G. Leeming, Shuai Nie, Joseph J. Byrne, Neil D. Young, Yuanting Zheng, Guangxu Ma, Pasi K. Korhonen, Anson V. Koehler, Nicholas A. Williamson, Andreas Hofmann, Bill C. H. Chang, Cécile Häberli, Jennifer Keiser, Abdul Jabbar, Brad E. Sleebs, Robin B. Gasser
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Parasitic roundworms (nematodes) cause destructive diseases, and immense suffering in humans and other animals around the world. The control of these parasites relies heavily on anthelmintic therapy, but treatment failures and resistance to these dru
Externí odkaz:
https://doaj.org/article/9c2e2b7509564909be768e1c02e98074
Akademický článek
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Akademický článek
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