Glycoproteins, glycolipids, and proteoglycans [electronic resource] . Part B / edited by Martin I. Horowitz.

Externí odkaz: Kolekce e-knih KNAV Registrovani uzivatele: plny text online 5 minut, dalsi pristup na vyzadani. Registered users: full text online 5 minutes, further access on request.

Chondroitin sulfate proteoglycans prevent immune cell phenotypic conversion and inflammation resolution via TLR4 in rodent models of spinal cord injury

Autor: Isaac Francos-Quijorna, Marina Sánchez-Petidier, Emily R. Burnside, Smaranda R. Badea, Abel Torres-Espin, Lucy Marshall, Fred de Winter, Joost Verhaagen, Victoria Moreno-Manzano, Elizabeth J. Bradbury

Publikováno v: Francos-Quijorna, I, Sánchez-Petidier, M, Burnside, E R, Badea, S R, Torres-Espin, A, Marshall, L, de Winter, F, Verhaagen, J, Moreno-Manzano, V & Bradbury, E J 2022, ' Chondroitin sulfate proteoglycans prevent immune cell phenotypic conversion and inflammation resolution via TLR4 in rodent models of spinal cord injury ', Nature Communications, vol. 13, 2933, pp. 1-23 . https://doi.org/10.1038/s41467-022-30467-5
Nature Communications 13(1), 2933 (2022). doi:10.1038/s41467-022-30467-5
Nature Communications, 13:2933, 1-23. Nature Publishing Group
Nature Communications, 13(1). Nature Publishing Group

Chondroitin sulfate proteoglycans (CSPGs) act as potent inhibitors of axonal growth and neuroplasticity after spinal cord injury (SCI). Here we reveal that CSPGs also play a critical role in preventing inflammation resolution by blocking the conversi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fd0bb333c02e27cae7a1e982bb75b79
https://hdl.handle.net/20.500.11755/f67715a7-bbf2-4a8b-98d8-6cbf3d869d3c

Osteomodulin attenuates smooth muscle cell osteogenic transition in vascular calcification

Autor: Nikolaos T. Skenteris, Till Seime, Anna Witasp, Eva Karlöf, Grzegorz B. Wasilewski, Marina A. Heuschkel, Armand M.G. Jaminon, Loureen Oduor, Robert Dzhanaev, Malin Kronqvist, Mariette Lengquist, Frederique E.C.M. Peeters, Magnus Söderberg, Rebecka Hultgren, Joy Roy, Lars Maegdefessel, Hildur Arnardottir, Eva Bengtsson, Isabel Goncalves, Thomas Quertermous, Claudia Goettsch, Peter Stenvinkel, Leon J. Schurgers, Ljubica Matic

Publikováno v: Clinical and Translational Medicine, 12(2):682. Springer Verlag

RATIONALE: Vascular calcification is a prominent feature of late-stage diabetes, renal and cardiovascular disease (CVD), and has been linked to adverse events. Recent studies in patients reported that plasma levels of osteomodulin (OMD), a proteoglyc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ad69652acc9678f086b6b848512733e
https://pubmed.ncbi.nlm.nih.gov/35184400

Skeletal Dysplasias Caused by Sulfation Defects

Autor: Paganini, C., Gramegna Tota, C., Superti-Furga, A., Rossi, A.

Publikováno v: International journal of molecular sciences, vol. 21, no. 8, pp. 2710

Proteoglycans (PGs) are macromolecules present on the cell surface and in the extracellular matrix that confer specific mechanical, biochemical, and physical properties to tissues. Sulfate groups present on glycosaminoglycans, linear polysaccharide c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1900::a5703ca21ffcd0b6b8c3168a7437f9fe
https://serval.unil.ch/resource/serval:BIB_0257CE41F1A7.P001/REF.pdf

Key Matrix Proteins Within the Pancreatic Islet Basement Membrane Are Differentially Digested During Human Islet Isolation

Autor: Paul Johnson, A.J. McBride, Karl E. Kadler, R H Vaughan, Elisa Maillard, P A Bateman, Patrik Rorsman, Anju Abraham, Stephen J. Hughes, Mark J. Dunne, Bing Han, J D Johnson, S E Cross, Reshma Ramracheya, A.J. Willcox

Publikováno v: Cross, S E, Vaughan, R H, Willcox, A J, McBride, A J, Abraham, A A, Han, B, Johnson, J D, Maillard, E, Bateman, P A, Ramracheya, R D, Rorsman, P, Kadler, K, Dunne, M, Hughes, S J & Johnson, P R V 2017, ' Key Matrix Proteins Within the Pancreatic Islet Basement Membrane Are Differentially Digested During Human Islet Isolation ', American Journal of Transplantation, vol. 17, no. 2, pp. 451-461 . https://doi.org/10.1111/ajt.13975
Europe PubMed Central

Clinical islet transplantation achieves insulin independence in selected patients, yet current methods for extracting islets from their surrounding pancreatic matrix are suboptimal. The islet basement membrane (BM) influences islet function and survi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3de02888758293324059e1b52d37ac05
https://doi.org/10.1111/ajt.13975