Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Proteins/chemistry/*metabolism"'
Autor:
Paul Johnson, Alejandra Tomas, Stephen R. Bloom, Piero Marchetti, Phoebe C Douzenis, Lorenzo Piemonti, Guy A. Rutter, Domenico Bosco, A. M. James Shapiro, Pauline Chabosseau, Ben Jones, Ivan R. Corrêa, Teresa Buenaventura, N Kanda
Publikováno v:
Diabetes, Vol. 67, No 3 (2018) pp. 385-399
The glucagon-like peptide 1 (GLP-1) receptor (GLP-1R) is a key target for type 2 diabetes (T2D) treatment. Because endocytic trafficking of agonist-bound receptors is one of the most important routes for regulation of receptor signaling, a better und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e3f1803ee2e9e82c99b109c69eb4fed
https://doi.org/10.2337/db17-0639
https://doi.org/10.2337/db17-0639
Autor:
Nicolas M. Doll, Thomas Widiez, Sophy Chamot, Gwyneth C. Ingram, Michael Hothorn, Satohiro Okuda, Satoshi Fujita, Andreas Schaller, S. Royek, Niko Geldner, Annick Stintzi
Publikováno v:
Science, Vol. 367, No 6476 (2020) pp. 431-435
Science
Science, American Association for the Advancement of Science, 2020, 367 (6476), pp.431-435. ⟨10.1126/science.aaz4131⟩
Science, 2020, 367 (6476), pp.431-435. ⟨10.1126/science.aaz4131⟩
Science
Science, American Association for the Advancement of Science, 2020, 367 (6476), pp.431-435. ⟨10.1126/science.aaz4131⟩
Science, 2020, 367 (6476), pp.431-435. ⟨10.1126/science.aaz4131⟩
Filling in the gaps In a plant seed, the embryo lies dormant surrounded by nutritive endosperm while awaiting suitable conditions to germinate. A hydrophobic cuticle around the embryo protects it from catastrophic water loss during the early days of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6eeabe59f5e93d433368e748c46ee17
https://pubmed.ncbi.nlm.nih.gov/31974252
https://pubmed.ncbi.nlm.nih.gov/31974252
Autor:
Bertrand Séraphin, Benedetta Sposito, Chris Oubridge, Kiyoshi Nagai, Eiji Obayashi, Anne-Marie M. van Roon, Andrew J. Newman
Publikováno v:
'RNA ', vol: 23, pages: 968-981 (2017)
RNA
RNA, Cold Spring Harbor Laboratory Press, 2017, 23 (6), pp.968-981. ⟨10.1261/rna.059378.116⟩
RNA
RNA, Cold Spring Harbor Laboratory Press, 2017, 23 (6), pp.968-981. ⟨10.1261/rna.059378.116⟩
Spliceosomal proteins Hsh49p and Cus1p are components of SF3b, which together with SF3a, Msl1p/Lea1p, Sm proteins, and U2 snRNA, form U2 snRNP, which plays a crucial role in pre-mRNA splicing. Hsh49p, comprising two RRMs, forms a heterodimer with Cus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cb4599ebeb50b190511b6438430c06d
https://epn-library.esrf.fr/flora/jsp/index_view_direct_anonymous.jsp?record=doc:PUB_ESRF:47208
https://epn-library.esrf.fr/flora/jsp/index_view_direct_anonymous.jsp?record=doc:PUB_ESRF:47208
Publikováno v:
Journal of Membrane Biology, vol. 213, no. 1, pp. 1-9
Sodium- and potassium-activated adenosine triphosphatases (Na,K-ATPase) is the ubiquitous active transport system that maintains the Na(+) and K(+) gradients across the plasma membrane by exchanging three intracellular Na(+) ions against two extracel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a24eaaf833cecd8886ea5c6f7401890
http://doc.rero.ch/record/319660/files/232_2006_Article_35.pdf
http://doc.rero.ch/record/319660/files/232_2006_Article_35.pdf
Autor:
Kay Grünewald, Cedric Leyrat, Pascale Schellenberger, Miriam Carolin Stoeber, Ari Helenius, C. Alistair Siebert
Publikováno v:
Proceedings of the National Academy of Sciences, Vol. 113, No 50 (2016) pp. E8069-E8078
'Proceedings of the National Academy of Sciences of the USA ', vol: 113, pages: E8069-E8078 (2016)
Europe PubMed Central
'Proceedings of the National Academy of Sciences of the USA ', vol: 113, pages: E8069-E8078 (2016)
Europe PubMed Central
Caveolae are invaginated plasma membrane domains involved in mechanosensing, signaling, endocytosis, and membrane homeostasis. Oligomers of membrane-embedded caveolins and peripherally attached cavins form the caveolar coat whose structure has remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff26269255a99a86f789c6ce9c294679
https://doi.org/10.1073/pnas.1616838113
https://doi.org/10.1073/pnas.1616838113
Autor:
Nahid Iglesias, Françoise Stutz, David Neuhaus, Sonja I. Kuhlmann, Sharon Soucek, Murray Stewart, Ji-Chun Yang, Katherine Mills-Lujan, Christoph Brockmann, Seth M. Kelly, Anita H. Corbett
Publikováno v:
Structure (London England : 1993)
Structure(London, England:1993)
Structure, Vol. 20, No 6 (2012) pp. 1007-18
Structure(London, England:1993)
Structure, Vol. 20, No 6 (2012) pp. 1007-18
Summary Polyadenylation regulation and efficient nuclear export of mature mRNPs both require the polyadenosine-RNA-binding protein, Nab2, which contains seven CCCH Zn fingers. We describe here the solution structure of fingers 5-7, which are necessar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1b0943a63bc77abb9be3fd41e98e447
Publikováno v:
Virology, 424(1), 33-44. United States (2012).
HIV-1 Vpu antagonizes the block to particle release mediated by CD317 (BST-2/HM1.24/Tetherin) via incompletely understood mechanisms. Vpu and CD317 partially reside in cholesterol-rich lipid rafts where HIV-1 budding preferentially occurs. Here we fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01f96f04dd2efffe67155362c36ec7ca
The present study provides molecular insight into the effect of thymol and carvacrol on the oxidative damage caused to myofibrillar proteins by a hydroxyl-radical generating system (HRGS). An innovative model system was designed, in which gels, prepa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddc8369e64d1037b0d7e743518f6087b
https://hdl.handle.net/11499/10817
https://hdl.handle.net/11499/10817
Autor:
Lionel Fontao, Luca Borradori, Nadja Begré, Bertrand Favre, Jamal-Eddine Bouameur, Prakash Lingasamy, Gloria M. Conover
Publikováno v:
Favre, Bertrand; Begré, Nadja; Bouameur, Jamal-Eddine; Lingasamy, Prakash; Conover, Gloria M; Fontao, Lionel; Borradori, Luca (2018). Desmoplakin interacts with the coil 1 of different types of intermediate filament proteins and displays high affinity for assembled intermediate filaments. PLoS ONE, 13(10), e0205038. Public Library of Science 10.1371/journal.pone.0205038
PLoS ONE
PLoS ONE, Vol 13, Iss 10, p e0205038 (2018)
PLOS ONE, Vol. 13, No 10 (2018) P. e0205038
PLoS ONE
PLoS ONE, Vol 13, Iss 10, p e0205038 (2018)
PLOS ONE, Vol. 13, No 10 (2018) P. e0205038
The interaction of intermediate filaments (IFs) with the cell-cell adhesion complexes desmosomes is crucial for cytoskeletal organization and cell resilience in the epidermis and heart. The intracellular desmosomal protein desmoplakin anchors IFs to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02d38afe983ae07a296fa426af545d0f
Autor:
H. Velocity Hughes, Yves V. Brun, Sean Pritchard, Edgar Huitema, Patrick H. Viollier, Kenneth C. Keiler
Publikováno v:
Proceedings of the National Academy of Sciences, Vol. 107, No 12 (2010) pp. 5599-604
Protein localization mechanisms dictate the functional and structural specialization of cells. Of the four polar surface organelles featured by the dimorphic bacterium Caulobacter crescentus , the stalk, a cylindrical extension of all cell envelope l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0384077e92e92c7c48de1731df561fc
https://doi.org/10.1073/pnas.0909119107
https://doi.org/10.1073/pnas.0909119107