Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Proteinkinasen."'
Autor:
Shevchenko, Ekaterina
Protein kinases were brought to the scientific community's attention with the remarkable approval of imatinib more than 20 years ago. Since then, enormous efforts have been made to identify, characterise, and investigate the dynamic and function of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d61eb98c5651d93679f92eff59d913a
https://hdl.handle.net/10900/136672
https://hdl.handle.net/10900/136672
Autor:
Steup, Christoph Daniel
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malig-nancies worldwide with an overall 5-year survival rate of about 9%. In many human PDACs, Protein kinase D1 (Prkd1) is downregulated by promoter methylation. This works aimed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afe2f3627e2f7597eb3c9195d2ade6c6
Autor:
Doris Niewolik, Klaus Schwarz
Publikováno v:
Nucleic acids research. 50(4)
The nuclease ARTEMIS and the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) are involved in the repair of physiological and pathogenic DNA double strand breaks. Both proteins are indispensable for the hairpin-opening activity in V(D)J reco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1bf90fecdc5487175a36b8bb176795b
https://pubmed.ncbi.nlm.nih.gov/35150269
https://pubmed.ncbi.nlm.nih.gov/35150269
Autor:
Lindemann, Marius
Tumorerkrankungen stellen weltweit die zweith��ufigste Todesursache dar und aufgrund der demographischen Entwicklung nimmt die Anzahl der Neuerkrankungen und Todesf��lle stetig zu. Zur Adressierung der Proteinkinase Akt, ein hochrelevantes Pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4d98bd5a603804b813f52fb567abe17
Autor:
Knape, Matthias J., Wallbott, Maximilian, Burghardt, Nicole C.G., Bertinetti, Daniela, Hornung, Jan, Schmidt, Sven H., Lorenz, Robin, Herberg, Friedrich W.
Publikováno v:
Cells, Vol 9, Iss 1548, p 1548 (2020)
Cells
Volume 9
Issue 6
Cells
Volume 9
Issue 6
cAMP-dependent protein kinase (PKA) is the major receptor of the second messenger cAMP and a prototype for Ser/Thr-specific protein kinases. Although PKA strongly prefers serine over threonine substrates, little is known about the molecular basis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::260a1619aca9fdb6aab1aaed08bf6d74
https://www.mdpi.com/2073-4409/9/6/1548
https://www.mdpi.com/2073-4409/9/6/1548
Autor:
Forsythe, Katherine H.
Publikováno v:
GMS Medizin – Bibliothek – Information, Vol 12, Iss 1-2, p Doc14 (2012)
[english] Research published in represents major advances in cell signaling in many disciplines, including the rapidly expanding areas of signaling networks, systems biology, synthetic biology, computation and modeling of regulatory pathways, and dru
Externí odkaz:
https://doaj.org/article/812e2069ccb042418c0016c6325effdd
Autor:
Pott, Leona Louise (M. Sc.)
Zur Identifizierung und Charakterisierung einer Proteinkinase als potentielles Therapietarget zur Behandlung des hepatozellulären Karzinoms wurden angereicherte Phosphoproteine aus Tumorgewebe und nicht tumorösem Gewebe quantitativ in einer 2D-DIGE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3579::2714e182b4a6802c2e7a44939bfdad85
https://hss-opus.ub.ruhr-uni-bochum.de/opus4/files/5566/diss.pdf
https://hss-opus.ub.ruhr-uni-bochum.de/opus4/files/5566/diss.pdf
Autor:
Pedrotti, Lorenzo
The control of energy homeostasis is of pivotal importance for all living organisms. In the last years emerged the idea that many stress responses that are apparently unrelated, are actually united by a common increase of the cellular energy demand.
Das primäre Ziel dieser Doktorarbeit war die kristallographische Untersuchung der beiden Kinasen Pim1 und PKA im Komplex mit kleinen Fragment-Molekülen, um ein mögliches Binden solcher Fragmente in den Proteinbindetaschen zu detektieren. In dem er
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f89d4fbafd5c13f7271247776e88c10