Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Proteindesign"'
Autor:
Le Quang Anh Tuan
Publikováno v:
Ho Chi Minh City Open University Journal of Science - Engineering and Technology, Vol 8, Iss 1, Pp 3-17 (2018)
Enzymes possessing many excellent properties such as high selectivity, consuming less energy, and producing less side products or waste have been widely applied as biocatalysts in pharmaceutical production and many industries such as biofuel, biomate
Externí odkaz:
https://doaj.org/article/4861e74adcb54675a19ff2e505fcf885
Autor:
Mühlbauer, Max Emanuel
ATP-synthesis is driven by the proton motive force generated by proteins of the respiratory chain. The mechanism by which these bio-machines convert redox potentials into an electrochemical gradient is of particular interest in bioenergetics. Here, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______518::c82e25b2aed9d2a6178a30729767484c
https://mediatum.ub.tum.de/doc/1650277/document.pdf
https://mediatum.ub.tum.de/doc/1650277/document.pdf
Autor:
Le Quang Anh Tuan
Publikováno v:
Ho Chi Minh City Open University Journal of Science-Engineering and Technology, Vol 8, Iss 1, Pp 3-17 (2018)
Enzymes possessing many excellent properties such as high selectivity, consuming less energy, and producing less side products or waste have been widely applied as biocatalysts in pharmaceutical production and many industries such as biofuel, biomate
Autor:
Dahlsson Leitao, Charles
Proteins are remarkable molecules with diverse and specialized functions playing essential roles in most biological processes. One such function is protecting us from diseases by the action of antibodies in our immune system that can recognize and me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::9624a14a2b3b87338ca22d028c9789ce
http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-309574
http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-309574
Publikováno v:
BMC Biotechnology 2014, 14:109 doi:10.1186/s12896-014-0109-5
Background: Trypsinogen is the inactive precursor of trypsin, a serine protease that cleaves proteins and peptides after arginine and lysine residues. In this study, human trypsinogen was used as a model protein to study the influence of electrostati
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A13121
https://ul.qucosa.de/api/qucosa%3A13121/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A13121/attachment/ATT-0/
Autor:
Baumgart, Mona
The aim of the thesis was to design artificial de novo protein systems with buried charged residues inside the hydrophobic protein core, and further, analyzing the conformational switching in Hsp90 by engineering a charged linker region. Artificial 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______518::465c7e5997dd1775c8c6e46e04f41934
https://mediatum.ub.tum.de/1615110
https://mediatum.ub.tum.de/1615110
C-C bonds are the basis for virtually all organic molecules on Earth. In nature, hundreds of different enzymes catalyze reactions in which C-C bonds are formed. A major task of these enzymes is the fixation of carbon, i.e. a C-C bond formation with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ba2cd221f8f7f87ad59d58f94ca5435
Autor:
Manz, Timo
In recent years, the clinical application of therapeutic antibodies has already significantly improved the therapy and prognosis of various malignant diseases. Notably, immunomodulating antibodies demonstrated the possibility to selectively modify th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______707::0570f1e537bb9d9abe3e9f0ef148aa83
https://hdl.handle.net/10900/112777
https://hdl.handle.net/10900/112777
Controlling protein crystallization by free energy guided design of interactions at crystal contacts
Autor:
Dariusch Hekmat, Robert Janowski, Dierk Niessing, Johannes Hermann, Daniel Bischoff, Martin Zacharias, Dirk Weuster-Botz, Phillip Grob
Publikováno v:
Crystals 11:588 (2021)
Crystals
Volume 11
Issue 6
Crystals, Vol 11, Iss 588, p 588 (2021)
Crystals
Volume 11
Issue 6
Crystals, Vol 11, Iss 588, p 588 (2021)
Protein crystallization can function as an effective method for protein purification or formulation. Such an application requires a comprehensive understanding of the intermolecular protein–protein interactions that drive and stabilize protein crys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a71e5b213a598d886751420c8ccf612
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=62255
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=62255
Autor:
Feiner, Rebecca, Kemker, Isabell, Krutzke, Lea, Allmendinger, Ellen, Mandell, Daniel J., Sewald, Norbert, Kochanek, Stefan, Müller, Kristian
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 9535, p 9535 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 24
International Journal of Molecular Sciences
Volume 21
Issue 24
The epidermal growth factor receptor (EGFR) plays a central role in the progression of many solid tumors. We used this validated target to analyze the de novo design of EGFR-binding peptides and their application for the delivery of complex payloads