Zobrazeno 1 - 10
of 415
pro vyhledávání: '"Protein structure modeling"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 10, p 5247 (2024)
Residue contact maps provide a condensed two-dimensional representation of three-dimensional protein structures, serving as a foundational framework in structural modeling but also as an effective tool in their own right in identifying inter-helical
Externí odkaz:
https://doaj.org/article/5cc0b899f8ea49ecbacc45c25703bd96
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1809 (2024)
Acquired immunodeficiency syndrome (AIDS) is caused by human immunodeficiency virus (HIV). HIV protease, reverse transcriptase, and integrase are targets of current drugs to treat the disease. However, anti-viral drug-resistant strains have emerged q
Externí odkaz:
https://doaj.org/article/48c302ca9e82447f9ca8c619d759a83f
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 185-201 (2023)
Circular permutation (CP) is a protein sequence rearrangement in which the amino- and carboxyl-termini of a protein can be created in different positions along the imaginary circularized sequence. Circularly permutated proteins usually exhibit conser
Externí odkaz:
https://doaj.org/article/c0ca2f20e5fe484a895ae68dc4d90a71
Autor:
Rosario Francisco-Velilla, Azman Embarc-Buh, Salvador Abellan, Francisco del Caño-Ochoa, Santiago Ramón-Maiques, Encarnacion Martinez-Salas
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 6182-6191 (2022)
Gemin5 is a multifunctional RNA binding protein (RBP) organized in domains with a distinctive structural organization. The protein is a hub for several protein networks performing diverse RNA-dependent functions including regulation of translation, a
Externí odkaz:
https://doaj.org/article/11165f1e4822453bbbe1cfc1803de8a1
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
In this paper we report the improvements and extensions of the UNRES server (https://unres-server.chem.ug.edu.pl) for physics-based simulations with the coarse-grained UNRES model of polypeptide chains. The improvements include the replacement of the
Externí odkaz:
https://doaj.org/article/3704a2487bc146ac996f336327ff6dd8
Publikováno v:
BMC Bioinformatics, Vol 22, Iss S10, Pp 1-24 (2021)
Abstract Background This work aims to help develop new protein engineering techniques based on a structural rearrangement phenomenon called circular permutation (CP), equivalent to connecting the native termini of a protein followed by creating new t
Externí odkaz:
https://doaj.org/article/1e35323f0cc64fd291ef378f48af54cd
Akademický článek
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Publikováno v:
Biomolecules, Vol 13, Iss 6, p 923 (2023)
Determining Secondary Structure Elements (SSEs) for any protein is crucial as an intermediate step for experimental tertiary structure determination. SSEs are identified using popular tools such as DSSP and STRIDE. These tools use atomic information
Externí odkaz:
https://doaj.org/article/a06d296bcd884e38adeaf295fac30c0b
Autor:
Alexey S. Nagel, Natalia V. Rudenko, Polina N. Luchkina, Anna P. Karatovskaya, Anna V. Zamyatina, Zhanna I. Andreeva-Kovalevskaya, Alexander V. Siunov, Fedor A. Brovko, Alexander S. Solonin
Publikováno v:
Molecules, Vol 28, Iss 8, p 3581 (2023)
Hemolysin II (HlyII) is one of the virulence factors of the opportunistic bacterium Bacillus cereus belonging to the group of β-pore-forming toxins. This work created a genetic construct encoding a large C-terminal fragment of the toxin (HlyIILCTD,
Externí odkaz:
https://doaj.org/article/ee19ecbec74a4b23b36357c358e69923