Zobrazeno 1 - 10
of 186
pro vyhledávání: '"Protein kinase C δ"'
Autor:
Hong-tao Jia, Yan-fei Shao, Xue-liang Zhou, Guang Yang, Ling Huang, Batuer Aikemu, Shu-chun Li, Cheng-sheng Ding, Xiao-dong Fan, Hi-ju Hong, Sen Zhang, Rui-jun Pan, Jing Sun
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
ObjectiveColorectal cancer (CRC) is the third cause of expected cancer deaths both in men and women in the U.S. and the third most commonly diagnosed cancer in China Targeted therapy has been proven to improve overall survival for unresectable metast
Externí odkaz:
https://doaj.org/article/e07bb65f26fd4090bed1b1617049814f
Akademický článek
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Publikováno v:
BMC Complementary Medicine and Therapies, Vol 20, Iss 1, Pp 1-14 (2020)
Abstract Background Previous studies have found that Hugan Qingzhi tablet (HQT) has significant lipid-lowering and antioxidant effects on non-alcoholic fatty liver disease (NAFLD). Moreover, the results of proteomic analysis confirmed that various pr
Externí odkaz:
https://doaj.org/article/d0b9c48eae3e48b689a9bc3237dbd4b4
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-13 (2020)
Abstract Background Upregulation of matrix metalloproteinase-9 (MMP-9) has been indicated as one of the inflammatory biomarkers. In the central nervous system (CNS), the MMP-9 is induced by several proinflammatory mediators and participates in the CN
Externí odkaz:
https://doaj.org/article/8c2f87c6291941a7bfb19306457c5298
Publikováno v:
Di-san junyi daxue xuebao, Vol 42, Iss 10, Pp 981-988 (2020)
Objective To investigate the effects of naringenin (NGN) on inflammatory injury after intracerebral hemorrhage (ICH) in rats and its possible molecular mechanism. Methods SD rats were randomly divided into sham group, ICH group, ICH+DMSO+PEG400 group
Externí odkaz:
https://doaj.org/article/2aec8ec540bc473e86f6a8b26b30f319
Autor:
Victor Calvo, Manuel Izquierdo
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
T cell receptor (TCR) and B cell receptor (BCR) stimulation by antigen presented on an antigen-presenting cell (APC) induces the formation of the immune synapse (IS), the convergence of secretory vesicles from T and B lymphocytes toward the centrosom
Externí odkaz:
https://doaj.org/article/556d6347496c4bddb1971a10ff0c507b
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Autor:
Linda Lei, Sabina Muhammad, Muthana Al-Obaidi, Neil Sebire, Iek Leng Cheng, Despina Eleftheriou, Paul Brogan
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 16, Iss 1, Pp 1-8 (2018)
Abstract Background We previously described an endogamous Pakistani kindred in whom we identified a novel homozygous missense mutation in the PRKCD gene encoding for protein kinase C δ (PKCδ) as a cause of monogenic systemic lupus erythematosus (SL
Externí odkaz:
https://doaj.org/article/d2e3c73b3b414ef98791e8f80d37f443
Autor:
Ana Bello-Gamboa, Marta Velasco, Solange Moreno, Gonzalo Herranz, Roxana Ilie, Silvia Huetos, Sergio Dávila, Alicia Sánchez, Jorge Bernardino De La Serna, Víctor Calvo, Manuel Izquierdo
Publikováno v:
Journal of Extracellular Vesicles, Vol 9, Iss 1 (2020)
T-cell receptor stimulation induces the convergence of multivesicular bodies towards the microtubule-organizing centre (MTOC) and the polarization of the MTOC to the immune synapse (IS). These events lead to exosome secretion at the IS. We describe h
Externí odkaz:
https://doaj.org/article/a25386762720464da87db4b4874789f9
Autor:
Gonzalo Herranz, Pablo Aguilera, Sergio Dávila, Alicia Sánchez, Bianca Stancu, Jesús Gómez, David Fernández-Moreno, Raúl de Martín, Mario Quintanilla, Teresa Fernández, Pablo Rodríguez-Silvestre, Laura Márquez-Expósito, Ana Bello-Gamboa, Alberto Fraile-Ramos, Víctor Calvo, Manuel Izquierdo
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Multivesicular bodies (MVB) are endocytic compartments that enclose intraluminal vesicles (ILVs) formed by inward budding from the limiting membrane of endosomes. In T lymphocytes, ILVs are secreted as Fas ligand-bearing, pro-apoptotic exosomes follo
Externí odkaz:
https://doaj.org/article/dfd47d83a52f49deab2729eb9e5caebe