Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Protein Structure, Tertiary/genetics"'
Autor:
Rudolf Grosschedl, Duygu Akbas, Dirk Schübeler, Robert Nechanitzky, Rabih Murr, Senthilkumar Ramamoorthy, Sören Boller, Lukas Burger
Publikováno v:
Immunity
Immunity, Vol. 44, No 3 (2016) pp. 527-541
Immunity, Vol. 44, No 3 (2016) pp. 527-541
Lymphopoiesis requires the activation of lineage-specific genes embedded in naive, inaccessible chromatin or in primed, accessible chromatin. The mechanisms responsible for de novo gain of chromatin accessibility, known as "pioneer" function, remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c23e9cb7044ab1cf64d6d8b293541ad
Autor:
Sergio Verjovski-Almeida, James E. Galagan, Ryan C. Kennedy, Zhiyong Xi, Jason R. Miller, Eric Eisenstadt, Kyanne R. Reidenbach, Robert V. Bruggner, Yu-Hui Rogers, Hadi Quesneville, Doreen Werner, Owen White, Alexander S. Raikhel, Mario Stanke, J. Spencer Johnston, Diane D. Lovin, Evgenia V. Kriventseva, Ian T. Paulsen, Kathryn S. Campbell, Norman H. Lee, Ewan Birney, Karyn Megy, Hean Koo, David Kulp, Shelby L. Bidwell, Jingsong Zhu, Philip Montgomery, Paolo Amedeo, Yongmei Zhao, Chinnappa D. Kodira, Javier Costas, Michael C. Schatz, Steven P. Sinkins, Claire M. Fraser-Liggett, Martin Shumway, Kurt LaButti, Akio Mori, Brendan J. Loftus, Manfred Grabherr, Eric O. Stinson, Frank H. Collins, Zhijian Jake Tu, Monique R. Coy, Matt Crawford, Janice P. Vanzee, William M. Gelbart, Joshua Orvis, Peter Arensburger, Chunhong Mao, Evgeny M. Zdobnov, Saul A. Kravitz, Suely Lopes Gomes, David DeCaprio, David G. Hogenkamp, Daniel Lawson, Dennis L. Knudson, David W. Severson, George Dimopoulos, Marcelo B. Soares, Sinéad B. O'Leary, Peter W. Atkinson, David M. Jaffe, Becky deBruyn, Martin Hammond, Ana L. T. O. Nascimento, Jim Biedler, Stefan Wyder, Jose M. C. Tubio, Bruce W. Birren, Catherine A. Hill, Chad Nusbaum, Eduardo Lee, Song Li, Susan E. Brown, Jennifer R. Wortman, James R. Hogan, Hamza El-Dorry, Qi Zhao, Linda Hannick, Carlos Frederico Martins Menck, Vishvanath Nene, Jonathan Crabtree, Steven L. Salzberg, Michael H. Holmes, Maria de Fatima Bonaldo, Quinghu Ren, Mihaela Pertea, Charles Roth, Evan Mauceli, Karin Eiglmeier, Horacio Naveira, Brian J. Haas, Qiandong Zeng, Neil F. Lobo, Jennifer R. Schneider
Publikováno v:
Science
Science, American Association for the Advancement of Science, 2007, 316 (5832), pp.1718-23. 〈10.1126/science.1138878〉
Science, American Association for the Advancement of Science, 2007, 316 (5832), pp.1718-23. ⟨10.1126/science.1138878⟩
Science, 2007, 316 (5832), pp.1718-23. ⟨10.1126/science.1138878⟩
Science, Vol. 316, No 5832 (2007) pp. 1718-1723
Science, American Association for the Advancement of Science, 2007, 316 (5832), pp.1718-23. 〈10.1126/science.1138878〉
Science, American Association for the Advancement of Science, 2007, 316 (5832), pp.1718-23. ⟨10.1126/science.1138878⟩
Science, 2007, 316 (5832), pp.1718-23. ⟨10.1126/science.1138878⟩
Science, Vol. 316, No 5832 (2007) pp. 1718-1723
We present a draft sequence of the genome of Aedes aegypti , the primary vector for yellow fever and dengue fever, which at ∼1376 million base pairs is about 5 times the size of the genome of the malaria vector Anopheles gambiae . Nearly 50% of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::701bca49fefccd61cb20d80a44096035
https://doi.org/10.1126/science.1138878
https://doi.org/10.1126/science.1138878
Publikováno v:
Long, H K, Blackledge, N P & Klose, R J 2013, ' ZF-CxxC domain-containing proteins, CpG islands and the chromatin connection ', Biochemical Society Transactions, vol. 41, no. 3, pp. 727-40 . https://doi.org/10.1042/BST20130028
Biochemical Society Transactions
Biochemical Society Transactions
Vertebrate DNA can be chemically modified by methylation of the 5 position of the cytosine base in the context of CpG dinucleotides. This modification creates a binding site for MBD (methyl-CpG-binding domain) proteins which target chromatin-modifyin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04d23e5886961723d395fb4798c63f76
https://ora.ox.ac.uk/objects/uuid:194ec326-8549-4a6f-a9fd-66f9001fc79c
https://ora.ox.ac.uk/objects/uuid:194ec326-8549-4a6f-a9fd-66f9001fc79c
Autor:
Cathrine Persson, Giampietro Corradin, Photini Sinnis, Alida Coppi, Mario Roggero, Eric R. James, Gabriele Pradel, Rita Tewari, Brandy L. Bennett, Ramya Natarajan
Publikováno v:
Journal of Experimental Medicine, vol. 208, no. 2, pp. 341-356
The Journal of Experimental Medicine
The Journal of Experimental Medicine
Conformational changes influence functional properties of circumsporozoite protein expressed on the surface of Plasmodium sporozoites.
Plasmodium sporozoites make a remarkable journey from the mosquito midgut to the mammalian liver. The sporozoi
Plasmodium sporozoites make a remarkable journey from the mosquito midgut to the mammalian liver. The sporozoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdf3ebc07eea930340d5856005712c06
https://doi.org/10.1084/jem.20101488
https://doi.org/10.1084/jem.20101488
Autor:
T. Tselios, Iakovos Lazaridis, Achille Gravanis, Olga Rassouli, George Deraos, Kostas Gkountelias, Maria Venihaki, George Liapakis
Publikováno v:
Molecular Pharmacology. 75:793-800
Upon binding of the corticotropin-releasing factor (CRF) analog sauvagine to the type 1 CRF receptor (CRF(1)), the amino-terminal portion of the peptide has been shown to lie near Lys257 in the receptor's second extracellular loop (EL2). To test the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fbb5d54e38766f401c49617f1cd939b
https://doi.org/10.1124/mol.108.052423
https://doi.org/10.1124/mol.108.052423
Autor:
Jun-ichi Furukawa, Shin-Ichiro Nishimura, Lucie Clementine Baudino, Yasuro Shinohara, J. Sjef Verbeek, Falk Nimmerjahn, Jeffery V. Ravetch, Franz Petry, Shozo Izui
Publikováno v:
Journal of Immunology, Vol. 181, No 6 (2008) pp. 4107-12
Four murine IgG subclasses display markedly different Fc-associated effector functions because of their differential binding to three activating IgG Fc receptors (FcγRI, FcγRIII, and FcγRIV) and C1q. Previous analysis of IgG subclass switch varian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07411b4eebdc685e984c87f6a2f4536a
https://doi.org/10.4049/jimmunol.181.6.4107
https://doi.org/10.4049/jimmunol.181.6.4107
Publikováno v:
Molecular and Biochemical Parasitology, 144(1), 86-93
The genetic diversity of a defined Plasmodium vivax population from the Venezuelan Amazon was evaluated by direct sequencing of the gene encoding the P. vivax merozoite surface protein-3alpha, Pvmsp3alpha. Three allele sizes (1.9, 1.4 and 1.1kb) were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36116f361ee43ef786f410661a20e545
https://doi.org/10.1016/j.molbiopara.2005.08.005
https://doi.org/10.1016/j.molbiopara.2005.08.005
Autor:
Patrice Francois, José M. Entenza, Philippe Moreillon, Eleonora Widmer, Pierre Vaudaux, Lionel Piroth, Jacques-Antoine Haefliger, Patrick Francioli, Bhanu Sinha, Yok-Ai Que, Mathias Herrmann
Publikováno v:
Journal of Experimental Medicine, Vol. 201, No 10 (2005) pp. 1627-1635
Journal of Experimental Medicine, vol. 201, no. 10, pp. 1627-1635
The Journal of Experimental Medicine
Journal of Experimental Medicine, vol. 201, no. 10, pp. 1627-1635
The Journal of Experimental Medicine
The expression of Staphylococcus aureus adhesins in Lactococcus lactis identified clumping factor A (ClfA) and fibronectin-binding protein A (FnBPA) as critical for valve colonization in rats with experimental endocarditis. This study further analyze
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::353957633eb738d59ca01b15bb660f0c
https://doi.org/10.1084/jem.20050125
https://doi.org/10.1084/jem.20050125
Autor:
Osakabe, A., Tachiwana, H., Takaku, M., Hori, T., Obuse, C., Kimura, Hiroshi, Fukagawa, T., Kurumizaka, H.
Publikováno v:
Journal of Cell Science.
In eukaryotes, transcription occurs in the chromatin context with the assistance of histone binding proteins, such as chromatin/nucleosome remodeling factors and histone chaperones. However, it is unclear how each remodeling factor or histone chapero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88978c6730bdf0f9896f95b94ec60f91
https://doi.org/10.1242/jcs.112623
https://doi.org/10.1242/jcs.112623
Publikováno v:
Wells, K L, Mou, C, Headon, D & Tucker, A 2011, ' Defects and rescue of the minor salivary glands in Eda pathway mutants ', Developmental Biology, vol. 349, no. 2, pp. 137-46 . https://doi.org/10.1016/j.ydbio.2010.10.012
Toll-like receptors (TLRs) are a family of pattern recognition receptors that are an important link between innate and adaptive immunity. Many vaccines incorporate ligands for TLRs as an adjuvant and are developed in rodent models, with the resulting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::087046b6fa02b1af676e9a83ecfdadee
https://hdl.handle.net/20.500.11820/a6b498c1-cc0e-4016-9c5e-94b050c1fb9e
https://hdl.handle.net/20.500.11820/a6b498c1-cc0e-4016-9c5e-94b050c1fb9e