Zobrazeno 1 - 10
of 3 108
pro vyhledávání: '"Protein Quality Control"'
Autor:
Satoshi Ninagawa, Masaki Matsuo, Deng Ying, Shuichiro Oshita, Shinya Aso, Kazutoshi Matsushita, Mai Taniguchi, Akane Fueki, Moe Yamashiro, Kaoru Sugasawa, Shunsuke Saito, Koshi Imami, Yasuhiko Kizuka, Tetsushi Sakuma, Takashi Yamamoto, Hirokazu Yagi, Koichi Kato, Kazutoshi Mori
Publikováno v:
eLife, Vol 12 (2024)
How the fate (folding versus degradation) of glycoproteins is determined in the endoplasmic reticulum (ER) is an intriguing question. Monoglucosylated glycoproteins are recognized by lectin chaperones to facilitate their folding, whereas glycoprotein
Externí odkaz:
https://doaj.org/article/42d5cb3e54fd4c2c93fd5d5ac18d10e8
Autor:
Theoni Margaritopoulou, Konstantinos Kotsaridis, Martina Samiotaki, Spyridon Nastos, Marinos Maratos, Ieronymos Zoidakis, Despoina Tsiriva, Stergios Pispas, Emilia Markellou
Publikováno v:
Plant Stress, Vol 14, Iss , Pp 100693- (2024)
The interaction of plants with pathogens during infection is a multifaceted process involving various molecules deriving from both partners. A current goal in combating pathogen virulence is to induce plant resistance using environmentally friendly c
Externí odkaz:
https://doaj.org/article/4c2028ce39c94745aa520a516819b635
Autor:
Franić, Dina 1, ‡, Pravica, Mihaela 1, ‡, Zubčić, Klara 1, Miles, Shawna 2, Bedalov, Antonio 2, 3, Boban, Mirta 1, ∗
Publikováno v:
In Journal of Biological Chemistry January 2025 301(1)
Akademický článek
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Autor:
Wiktoria Sztangierska, Hubert Wyszkowski, Maria Pokornowska, Klaudia Kochanowicz, Michal Rychłowski, Krzysztof Liberek, Agnieszka Kłosowska
Publikováno v:
eLife, Vol 13 (2024)
Hsp70 is a key cellular system counteracting protein misfolding and aggregation, associated with stress, ageing, and disease. Hsp70 solubilises aggregates and aids protein refolding through substrate binding and release cycles regulated by co-chapero
Externí odkaz:
https://doaj.org/article/f21c38e791d7464183add8aeaab0c303
Autor:
Stewart, Mariah 1, Schisler, Jonathan C. 1, 2, ∗
Publikováno v:
In Journal of Biological Chemistry December 2024 300(12)
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-33 (2024)
Abstract Canavan disease is an autosomal recessive and lethal neurological disorder, characterized by the spongy degeneration of the white matter in the brain. The disease is caused by a deficiency of the cytosolic aspartoacylase (ASPA) enzyme, which
Externí odkaz:
https://doaj.org/article/d16159e3d96d4829b453b859feaeacf5
Autor:
Stefano Magnati, Enrico Bracco
Publikováno v:
Biophysica, Vol 4, Iss 2, Pp 158-167 (2024)
In the last few decades, the traditional paradigm of teleonomy, in which the amino acid sequence of a protein is tightly associated with its structure and, in turn, with its function, has been partially undermined. The idea of a protein as a two-stat
Externí odkaz:
https://doaj.org/article/0b087316a3174ade84b0ecdb5a46eb10
Autor:
Aseel A. Jawabri, Anne John, Mohammad A. Ghattas, Radwa E. Mahgoub, Mohammad I. K. Hamad, Maha T. Barakat, Bindu Shobi, Hinda Daggag, Bassam R. Ali
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
BackgroundFamilial hypercholesterolemia (FH) is an autosomal dominant disorder characterized by increased LDL-cholesterol levels. About 85% of FH cases are caused by LDLR mutations encoding the low-density lipoprotein receptor (LDLR). LDLR is synthes
Externí odkaz:
https://doaj.org/article/853e9696b4b94268b68dc340efeeb0de
Publikováno v:
BMC Neuroscience, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Background It has been suggested that exercise training and postbiotic supplement could decelerate the progress of functional and biochemical deterioration in double transgenic mice overexpresses mutated forms of the genes for human amyloid
Externí odkaz:
https://doaj.org/article/0fab0ba198404650aead1672eaeeae8b