Multi-step HPLC fractionation enabled in-depth and unbiased characterization of histone PTMs.

Autor: Zhao W; Department of Thoracic Surgery, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai 200433, China., Chen K; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; University of Chinese Academy of Sciences, Beijing 101408, China; Translational Research Institute of Brain and Brain-Like Intelligence, Shanghai Fourth People's Hospital and Cancer Center, School of Medicine, Tongji University, Shanghai 200434, China., Zhang J; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; University of Chinese Academy of Sciences, Beijing 101408, China., Zhang M; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; School of Pharmacy, Fudan University, Shanghai 201203, China., Guo J; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; University of Chinese Academy of Sciences, Beijing 101408, China., Xie D; Department of Thoracic Surgery, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai 200433, China., Xu J; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan 528400, China. Electronic address: jyxu@simm.ac.cn., Tan M; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; University of Chinese Academy of Sciences, Beijing 101408, China; Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan 528400, China. Electronic address: mjtan@simm.ac.cn.

Publikováno v: Journal of chromatography. A [J Chromatogr A] 2024 Nov 08; Vol. 1736, pp. 465368. Date of Electronic Publication: 2024 Sep 10.

Histone lactylation drives CD8 ⁺ T cell metabolism and function.

Autor: Raychaudhuri D; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Singh P; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Chakraborty B; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Hennessey M; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Tannir AJ; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Byregowda S; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Natarajan SM; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Trujillo-Ocampo A; Department of Hematopoietic Biology and Malignancy, Division of Cancer Medicine, MD Anderson Cancer Center, Houston, TX, USA., Im JS; Department of Hematopoietic Biology and Malignancy, Division of Cancer Medicine, MD Anderson Cancer Center, Houston, TX, USA.; The University of Texas MD Anderson Cancer Center, UTHealth Graduate School of Biomedical Sciences, Houston, TX, USA.; Department of Stem Cell Transplantation and Cellular Therapy, Division of Cancer Medicine, MD Anderson Cancer Center, Houston, TX, USA., Goswami S; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. sgoswami@mdanderson.org.; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. sgoswami@mdanderson.org.; James P. Allison Institute, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. sgoswami@mdanderson.org.

Publikováno v: Nature immunology [Nat Immunol] 2024 Nov; Vol. 25 (11), pp. 2140-2151. Date of Electronic Publication: 2024 Oct 07.

Unraveling the protein post-translational modification landscape: Neuroinflammation and neuronal death after stroke.

Autor: Tao J; Department of Pain Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, P. R. China; Department of Human Anatomy, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, P. R. China., Li J; Department of Human Anatomy, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, P. R. China., Fan X; Department of Pain Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, P. R. China., Jiang C; Department of Neurology, People's Hospital of Zhengzhou University & Henan Provincial People's Hospital, Zhengzhou, Henan 450003, P. R. China., Wang Y; Department of Human Anatomy, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, P. R. China., Qin M; Department of Human Anatomy, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, P. R. China., Nikfard Z; Department of Human Anatomy, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, P. R. China; School of International Education, Zhengzhou University, Zhengzhou, Henan 450001, P. R. China., Nikfard F; Department of Human Anatomy, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, P. R. China; School of International Education, Zhengzhou University, Zhengzhou, Henan 450001, P. R. China., Wang Y; Clinical Systems Biology Laboratories, The First Affiliated Hospital, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, Henan 450000, P. R. China., Zhao T; Department of Neurology, People's Hospital of Zhengzhou University & Henan Provincial People's Hospital, Zhengzhou, Henan 450003, P. R. China., Xing N; Department of Anesthesiology, Pain and Perioperative Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450000, P. R. China., Zille M; Department of Pharmaceutical Sciences, Division of Pharmacology and Toxicology, University of Vienna, Vienna 1090, Austria., Wang J; Department of Human Anatomy, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, P. R. China. Electronic address: wangjunmin@zzu.edu.cn., Zhang J; Department of Neurology, People's Hospital of Zhengzhou University & Henan Provincial People's Hospital, Zhengzhou, Henan 450003, P. R. China. Electronic address: zhangjiewen9900@126.com., Chen X; Department of Human Anatomy, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, P. R. China. Electronic address: chenxm@zzu.edu.cn., Wang J; Department of Pain Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, P. R. China; Department of Human Anatomy, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, P. R. China. Electronic address: jianwang2020@outlook.com.

Publikováno v: Ageing research reviews [Ageing Res Rev] 2024 Nov; Vol. 101, pp. 102489. Date of Electronic Publication: 2024 Sep 12.

Pancreatic β‑cell apoptosis in type 2 diabetes is related to post‑translational modifications of p53 (Review).

Autor: Flores-López LA; Biomolecules and Infant Health Laboratory, National Council of Humanities, Sciences and Technologies‑National Institute of Pediatrics, Ministry of Health, Mexico City 04530, Mexico., Enríquez-Flores S; Biomolecules and Infant Health Laboratory, National Institute of Pediatrics, Ministry of Health, Mexico City 04530, Mexico., De La Mora-De La Mora I; Biomolecules and Infant Health Laboratory, National Institute of Pediatrics, Ministry of Health, Mexico City 04530, Mexico., García-Torres I; Biomolecules and Infant Health Laboratory, National Institute of Pediatrics, Ministry of Health, Mexico City 04530, Mexico., López-Velázquez G; Biomolecules and Infant Health Laboratory, National Institute of Pediatrics, Ministry of Health, Mexico City 04530, Mexico., Viedma-Rodríguez R; Morphophysiology Unit, Faculty of Higher Studies, Iztacala, National Autonomous University of Mexico, Tlalnepantla 54090, Mexico., Ávalos-Rodríguez A; Department of Agricultural and Animal Production, Metropolitan Autonomous University‑Xoch, Mexico City 04960, México., Contreras-Ramos A; Molecular Biology Research Laboratory, Children's Hospital of Mexico Federico Gomez, Mexico City 06720, Mexico., Ortega-Camarillo C; Medical Research Unit in Biochemistry, Specialties Hospital, National Medical Center SXXI, Mexican Social Security Institute, Mexico City 06720, Mexico.

Publikováno v: Molecular medicine reports [Mol Med Rep] 2024 Nov; Vol. 30 (5). Date of Electronic Publication: 2024 Sep 02.

Application of crotonylation modification in pan-vascular diseases.

Autor: Yan W; Oriental Pan-vascular Devices Innovation College, University of Shanghai for Science and Technology, Shanghai, China., Zhang Y; Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China., Dai Y; Oriental Pan-vascular Devices Innovation College, University of Shanghai for Science and Technology, Shanghai, China.; Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China.; National Clinical Research Center for Interventional Medicine, Shanghai, China., Ge J; Oriental Pan-vascular Devices Innovation College, University of Shanghai for Science and Technology, Shanghai, China.; Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China.; National Clinical Research Center for Interventional Medicine, Shanghai, China.

Publikováno v: Journal of drug targeting [J Drug Target] 2024 Nov; Vol. 32 (9), pp. 996-1004. Date of Electronic Publication: 2024 Jul 04.