Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Protein Precursors/genetics/*metabolism"'
Autor:
François Pattou, Frans Schuit, Thierry Berney, Philippe A. Halban, Jan A. Ehses, Roel Quintens, Marc Y. Donath, Geert A. Martens, Daniel Pipeleers, Julie Kerr-Conte, Helga Ellingsgaard, Eva Hammar, Leentje Van Lommel
Publikováno v:
Proceedings of the National Academy of Sciences, Vol. 105, No 35 (2008) pp. 13163-8
Interleukin-6 (IL-6) is systemically elevated in obesity and is a predictive factor to develop type 2 diabetes. Pancreatic islet pathology in type 2 diabetes is characterized by reduced β-cell function and mass, an increased proportion of α-cells r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2407c6316e9553ef3cbaa0de2d907ab8
https://doi.org/10.1073/pnas.0801059105
https://doi.org/10.1073/pnas.0801059105
Publikováno v:
Journal of Biological Chemistry, Vol. 284, No 29 (2009) pp. 19420-6
The new interleukin (IL)-1 family cytokine IL-33 is synthesized as a 30-kDa precursor. Like pro-IL-1beta, human pro-IL-33 was reported to be cleaved by caspase-1 to generate an 18-kDa fragment, which is sufficient to activate signaling by the IL-33 r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aabf157a455455b4c7cb2c0514f67b3
https://europepmc.org/articles/PMC2740567/
https://europepmc.org/articles/PMC2740567/
Publikováno v:
EMBO Journal, Vol. 15, No 3 (1996) pp. 468-478
The cytosolic and secreted, N-glycosylated, forms of plasminogen activator inhibitor-2 (PAI-2) are generated by facultative translocation. To study the molecular events that result in the bi-topological distribution of proteins, we determined in vitr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3189b126a618488ed04aafabd8503b7
https://archive-ouverte.unige.ch/unige:8633
https://archive-ouverte.unige.ch/unige:8633