Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Protein Multimerization/drug effects"'
Publikováno v:
ChemBioChem, 19(23), 2490-2494. Wiley-VCH Verlag
Chembiochem
Chembiochem
Caspase‐8 constructs featuring an N‐terminal FGG sequence allow for selective twofold recognition by cucurbit[8]uril, which leads to an increase of the enzymatic activity in a cucurbit[8]uril dose‐dependent manner. This supramolecular switching
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0fdb701117397593ac304bbfd4cf9af
https://doi.org/10.1002/cbic.201800521
https://doi.org/10.1002/cbic.201800521
Publikováno v:
Royal, A A, Tinker, A & Harmer, S C 2017, ' Phosphatidylinositol-4,5-bisphosphate is required for KCNQ1/KCNE1 channel function but not anterograde trafficking ', PLoS ONE, vol. 12, no. 10, e0186293 . https://doi.org/10.1371/journal.pone.0186293
PLoS ONE
PLoS ONE, Vol 12, Iss 10, p e0186293 (2017)
PLoS ONE
PLoS ONE, Vol 12, Iss 10, p e0186293 (2017)
The slow delayed-rectifier potassium current (IKs) is crucial for human cardiac action potential repolarization. The formation of IKs requires co-assembly of the KCNQ1 α-subunit and KCNE1 β-subunit, and mutations in either of these subunits can lea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9934a78462ca46553876bde14dd757dd
https://research-information.bris.ac.uk/en/publications/e514aac4-3f9f-4fe8-bf0c-8fe083982c1b
https://research-information.bris.ac.uk/en/publications/e514aac4-3f9f-4fe8-bf0c-8fe083982c1b
Publikováno v:
The Journal of Biological Chemistry
The Journal of biological chemistry
Journal of Biological Chemistry, Vol. 286, No 42 (2011) pp. 36448-59
The Journal of biological chemistry
Journal of Biological Chemistry, Vol. 286, No 42 (2011) pp. 36448-59
Background: STIM1 oligomerization upon endoplasmic reticulum (ER) Ca2+ depletion activates store-operated Ca2+ entry (SOCE) channels, but whether this mechanism is reversible is unknown. Results: STIM1 de-oligomerization upon ER Ca2+ refilling requir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1239165f14308202827d94c5c9e9c34d
https://doi.org/10.1074/jbc.m111.269415
https://doi.org/10.1074/jbc.m111.269415
Publikováno v:
Molecular Biology of the Cell, Vol. 25, No 7 (2014) pp. 1061-72
Molecular Biology of the Cell
Molecular Biology of the Cell
VEGF secretion is studied using VEGF165-GFP chimera. Efficient secretion requires Sar1- and Arf1-dependent steps and glycosylation in the Golgi. VEGF is retained in the outer surface of the plasma membrane, and shedding with other membrane components
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::310be6f5c9c992943c83895f755c6edd
https://archive-ouverte.unige.ch/unige:74474
https://archive-ouverte.unige.ch/unige:74474
Autor:
Marie-Laure Parmentier, Florence Maschat, Yasmina Talmat-Amar, Sophie Layalle, Nathalie Bonneaud, Yoan Arribat
Publikováno v:
PLoS ONE
PLoS ONE, Public Library of Science, 2013, 8 (7), pp.e68775. ⟨10.1371/journal.pone.0068775⟩
PLoS ONE, Vol 8, Iss 7, p e68775 (2013)
PLoS ONE, Public Library of Science, 2013, 8 (7), pp.e68775. ⟨10.1371/journal.pone.0068775⟩
PLoS ONE, Vol 8, Iss 7, p e68775 (2013)
Background Huntington’s disease (HD) is caused by the abnormal expansion of the polyglutamine tract in the human Huntingtin protein (polyQ-hHtt). Although this mutation behaves dominantly, huntingtin loss of function also contributes to HD pathogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55e347a78c513f4a7e799d11ba25ba97
https://hal.archives-ouvertes.fr/hal-01984749/file/pone.0068775.pdf
https://hal.archives-ouvertes.fr/hal-01984749/file/pone.0068775.pdf
Autor:
Anja K. Bosserhoff, Wolfram Gronwald, Burkhard König, Jennifer Schmidt, Alexander Riechers, Raphael Stoll, T. Amann, Florian Fink, Thilo Spruss, Claus Hellerbrand
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 5, p e37941 (2012)
PLoS ONE, Vol 7, Iss 5, p e37941 (2012)
Melanoma is the most aggressive form of skin cancer, with fast progression and early dissemination mediated by the melanoma inhibitory activity (MIA) protein. Here, we discovered that dimerization of MIA is required for functional activity through mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27b1f43c43398b7f705bace38faf9e0e
Autor:
René Lerch, Mohamed Asrih, Corinne Pellieux, Irène Papageorgiou, Christophe Albert Montessuit
Publikováno v:
American Journal of Physiology. Endocrinology and Metabolism, Vol. 301, No 5 (2011) pp. E836-43
American journal of physiology. Endocrinology and metabolism
American journal of physiology. Endocrinology and metabolism
We previously demonstrated that microtubule disruption impairs stimulation of glucose uptake in cardiomyocytes and that 9-cis retinoic acid (9cRA) treatment preserved both microtubule integrity and stimulated glucose transport. Herein we investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0f4ffcc3443c0d1cdb59659732d946b
https://archive-ouverte.unige.ch/unige:88465
https://archive-ouverte.unige.ch/unige:88465
Autor:
Aude Guillabert, Hideaki Yano, Patricia de Nadai, Jonathan A. Javitch, Jean-Yves Springael, Eneko Urizar, Marc Parmentier, Denis Sohy
Publikováno v:
The Journal of biological chemistry, 284 (45
Chemokine receptors constitute an attractive family of drug targets in the frame of inflammatory diseases. However, targeting specific chemokine receptors may be complicated by their ability to form dimers or higher order oligomers. Using a combinati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d159ffa25aee584568b7c24efff48370
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/52294
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/52294