Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Protein MDM2 [gnd]"'
Autor:
Hao-Chen Tang, Rajesh Singh, Alejandro Rojas-Fernandez, Andreas Marquardt, Martin Scheffner, Saravanakumar Iyappan, Hans-Peter Wollscheid
Publikováno v:
Journal of Biological Chemistry. 285:33065-33072
The related RING domain proteins MdmX and Mdm2 are best known for their role as negative regulators of the tumor suppressor p53. However, although Mdm2 functions as a ubiquitin ligase for p53, MdmX does not have appreciable ubiquitin ligase activity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba2db1eed9a25ae25322cad93414100d
https://doi.org/10.1074/jbc.m110.115113
https://doi.org/10.1074/jbc.m110.115113
Autor:
Rojas Fernandez, Alejandro
In response to stress (i.e. DNA damage, nucleolar or oxidative stress), mammalian cells stop their cell cycle and induce the transcription of a group of genes involved in repair of the damage. When the damage exceeds the natural barriers, the cells d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______715::ab26be2901ec7e3442d349cf969837d2
Autor:
Wollscheid, Hans-Peter
Die Konjugation mit Ubiquitin ist eine wichtige posttranslationale Modifikation in fast allen zellulären Signalwegen. Neben den gut untersuchten K48-Ubiquitinketten, die das Substratprotein zum proteasomalen Abbau markieren, bilden anders verknüpft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______715::995e941e274ba008205c104196889ff0