Zobrazeno 1 - 10
of 4 252
pro vyhledávání: '"Protein Kinase R"'
Autor:
Teruhiko Yoshida, Khun Zaw Latt, Avi Z Rosenberg, Briana A Santo, Komuraiah Myakala, Yu Ishimoto, Yongmei Zhao, Shashi Shrivastav, Bryce A Jones, Xiaoping Yang, Xiaoxin X Wang, Vincent M Tutino, Pinaki Sarder, Moshe Levi, Koji Okamoto, Cheryl A Winkler, Jeffrey B Kopp
Publikováno v:
eLife, Vol 12 (2024)
HIV disease remains prevalent in the USA and chronic kidney disease remains a major cause of morbidity in HIV-1-positive patients. Host double-stranded RNA (dsRNA)-activated protein kinase (PKR) is a sensor for viral dsRNA, including HIV-1. We show t
Externí odkaz:
https://doaj.org/article/30612ed355a4430f8889c67842e2d30b
Publikováno v:
Animal Cells and Systems, Vol 27, Iss 1, Pp 171-179 (2023)
ABSTRACTChloromethylisothiazolinone (CMIT), a humidifier disinfectant, is known to be toxic to the respiratory system. While the toxic effect of CMIT on the lungs has been widely investigated, its effect on the skin is well unknown. In this study, we
Externí odkaz:
https://doaj.org/article/a886badd3bf84f77b579b5c7b9824f3f
Autor:
Dewi Megawati, Jeannine N. Stroup, Chorong Park, Taylor Clarkson, Loubna Tazi, Greg Brennan, Stefan Rothenburg
Publikováno v:
Viruses, Vol 16, Iss 7, p 1095 (2024)
Yaba monkey tumor virus (YMTV) and Tanapox virus (TPV) are members of the Yatapoxvirus genus and can infect humans and other primates. Despite the threat posed by yatapoxviruses, the factors determining their host range are poorly understood. In this
Externí odkaz:
https://doaj.org/article/0bdd70e011e740ef99df345558f52e04
Publikováno v:
Viruses, Vol 16, Iss 7, p 1027 (2024)
Negative-strand RNA viruses form cytoplasmic inclusion bodies (IBs) representing virus replication foci through phase separation or biomolecular condensation of viral and cellular proteins, as a hallmark of their infection. Alternatively, mammalian c
Externí odkaz:
https://doaj.org/article/c2bfd584dc8a40568301cda570ebc58d
Autor:
Jimin Yoon, Minseok Lee, Ahsan Ausaf Ali, Ye Rim Oh, Yong Seok Choi, Sujin Kim, Namseok Lee, Se Gwang Jang, Seonghyeon Park, Jin-Haeng Chung, Seung-Ki Kwok, Joon Young Hyon, Seunghee Cha, Yun Jong Lee, Sung Gap Im, Yoosik Kim
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 30, Iss , Pp 257-269 (2022)
Sjӧgren’s syndrome (SS) is a systemic autoimmune disease that targets the exocrine glands, resulting in impaired saliva and tear secretion. To date, type I interferons (I-IFNs) are increasingly recognized as pivotal mediators in SS, but their endo
Externí odkaz:
https://doaj.org/article/783f6acfaa9946fe9e26b25868b4fb13
Autor:
Benjamin Dodd, Stephanie L. Moon
Publikováno v:
Dystonia, Vol 2 (2023)
Dystonia is a progressive neurological motor disease with few treatment options and no cure. This review synthesizes the results of recent studies that implicate protein kinase R in mediating the molecular mechanisms of dystonia pathogenesis. Mutatio
Externí odkaz:
https://doaj.org/article/530c370d90a54c888aae274cacc490eb
Akademický článek
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Akademický článek
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Autor:
Qian Li, Yu‐Heng Zhao, Cheng Xu, Ye‐Lin Liang, Yin Zhao, Qing‐Mei He, Jun‐Yan Li, Kai‐Lin Chen, Han Qiao, Na Liu, Jun Ma, Lei Chen, Ying‐Qin Li
Publikováno v:
Advanced Science, Vol 10, Iss 8, Pp n/a-n/a (2023)
Abstract Senescence is associated with tumor metastasis and chemotherapy resistance, yet the mechanisms remain elusive. Here, it is identified that nasopharyngeal carcinoma (NPC) patients who developed distant metastasis are characterized by senescen
Externí odkaz:
https://doaj.org/article/e2afdafc1b844f9da98b68f00aa26fcb
Akademický článek
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