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pro vyhledávání: '"Protein Kinase B (PKB Akt)"'
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Akademický článek
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Publikováno v:
In Arabian Journal of Chemistry May 2017 10 Supplement 2:S2182-S2195
Autor:
Yang Liu, Fu-Ju Chou, Fengchao Lang, Meili Zhang, Hua Song, Wei Zhang, Dionne L. Davis, Nicole J. Briceno, Yang Zhang, Patrick J. Cimino, Kareem A. Zaghloul, Mark R. Gilbert, Terri S. Armstrong, Chunzhang Yang
Publikováno v:
Clinical Cancer Research. 29:1305-1316
Purpose: Mutations of the isocitrate dehydrogenase (IDH) gene are common genetic mutations in human malignancies. Increasing evidence indicates that IDH mutations play critical roles in malignant transformation and progression. However, the therapeut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fa7df61b86c3808bfd25f0cb3f00985
https://doi.org/10.1158/1078-0432.ccr-22-3179
https://doi.org/10.1158/1078-0432.ccr-22-3179
Autor:
Roychoudhury, Sanghita, Mondal, Nandan Kumar, Mukherjee, Sayali, Dutta, Anindita, Siddique, Shabana, Ray, Manas Ranjan
Publikováno v:
In Toxicology and Applied Pharmacology 15 February 2012 259(1):45-53
Autor:
Chunzhang Yang, Terri S. Armstrong, Mark R. Gilbert, Kareem A. Zaghloul, Patrick J. Cimino, Yang Zhang, Nicole J. Briceno, Dionne L. Davis, Wei Zhang, Hua Song, Meili Zhang, Fengchao Lang, Fu-Ju Chou, Yang Liu
Purpose:Mutations of the isocitrate dehydrogenase (IDH) gene are common genetic mutations in human malignancies. Increasing evidence indicates that IDH mutations play critical roles in malignant transformation and progression. However, the therapeuti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ccd0d5791dd9d1748ae6663652ccb93
https://doi.org/10.1158/1078-0432.c.6533045
https://doi.org/10.1158/1078-0432.c.6533045
Autor:
Chunzhang Yang, Terri S. Armstrong, Mark R. Gilbert, Kareem A. Zaghloul, Patrick J. Cimino, Yang Zhang, Nicole J. Briceno, Dionne L. Davis, Wei Zhang, Hua Song, Meili Zhang, Fengchao Lang, Fu-Ju Chou, Yang Liu
(A) Heatmap of gene expression profile for glioma specimen. The leading edge of the KEGG_MTOR_SIGNALING_PATHWAY geneset was shown. (B) Dose-response curve measured the cell viability in IDH1WT NHA cells in response to TMZ/Ipa combination treatment. (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28c9fa45c7b8a8dec8b60c4994cb6658
https://doi.org/10.1158/1078-0432.22494883
https://doi.org/10.1158/1078-0432.22494883
Autor:
Chunzhang Yang, Terri S. Armstrong, Mark R. Gilbert, Kareem A. Zaghloul, Patrick J. Cimino, Yang Zhang, Nicole J. Briceno, Dionne L. Davis, Wei Zhang, Hua Song, Meili Zhang, Fengchao Lang, Fu-Ju Chou, Yang Liu
Patient sample information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ac15ea6a1ee010303dbcad11170f830
https://doi.org/10.1158/1078-0432.22489808.v1
https://doi.org/10.1158/1078-0432.22489808.v1
Publikováno v:
In Journal of Biological Chemistry 14 May 2010 285(20):15038-15047
Publikováno v:
Arabian Journal of Chemistry, Vol 10, Iss S2, Pp S2182-S2195 (2017)
Protein kinase B (PKB/Akt) regulates all aspects of cell growth, differentiation, and division. PKB/Akt has recently garnered a great deal of attention as a promising molecular target for cancer therapy due to its involvement in the development of se
Externí odkaz:
https://doaj.org/article/1d4321fb05bf448c8039eeb21fd29ef8