Zobrazeno 1 - 10
of 885
pro vyhledávání: '"Protein Kinase A (PKA)"'
Autor:
Shimrit Oz, Tal Keren-Raifman, Tom Sharon, Suraj Subramaniam, Tamara Pallien, Moshe Katz, Vladimir Tsemakhovich, Anastasiia Sholokh, Baraa Watad, Debi Ranjan Tripathy, Giorgia Sasson, Orna Chomsky-Hecht, Leonid Vysochek, Maike Schulz-Christian, Claudia Fecher-Trost, Kerstin Zühlke, Daniela Bertinetti, Friedrich W. Herberg, Veit Flockerzi, Joel A. Hirsch, Enno Klussmann, Sharon Weiss, Nathan Dascal
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-22 (2024)
Abstract Background The β-adrenergic augmentation of cardiac contraction, by increasing the conductivity of L-type voltage-gated CaV1.2 channels, is of great physiological and pathophysiological importance. Stimulation of β-adrenergic receptors (β
Externí odkaz:
https://doaj.org/article/52f4e02d97674c5baf869fd677bf8ea7
Autor:
Susrutha Puthanmadhom Narayanan, Abdalla M. Wedn, Osama Shiraz Shah, Jian Chen, Daniel D. Brown, Priscilla F. McAuliffe, Steffi Oesterreich, Adrian V. Lee
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-14 (2024)
Abstract Objective Invasive lobular breast cancer (ILC) is the most common special type of breast cancer and has unique clinicopathological and molecular hallmarks that differentiate it from the more common invasive carcinoma—no special type (NST).
Externí odkaz:
https://doaj.org/article/c69028712e1246c48c93d4e17467130a
Publikováno v:
eLife, Vol 13 (2024)
Protein kinase A (PKA) plays essential roles in diverse cellular functions. However, the spatiotemporal dynamics of endogenous PKA upon activation remain debated. The classical model predicts that PKA catalytic subunits dissociate from regulatory sub
Externí odkaz:
https://doaj.org/article/7a1ecb86412c48babe8dd9a9434eaacf
Autor:
Przygrodzka, Emilia 1, ∗, Bhinderwala, Fatema 2, Powers, Robert 2, 3, McFee, Renee M. 4, Cupp, Andrea S. 5, Wood, Jennifer R. 5, Davis, John S. 1, 6, ∗
Publikováno v:
In Journal of Biological Chemistry January 2025 301(1)
Autor:
JIN Bu, CHEN Hanzhang, XU Hudong, CHEN Wanyu, YUAN Ying, ZHAO Tingting, HUANG Xiaolei, HE Jialu, YU Hong
Publikováno v:
Shanghai Jiaotong Daxue xuebao. Yixue ban, Vol 44, Iss 3, Pp 325-333 (2024)
Objective·To investigate the effects of trimethylamine oxide (TMAO) on cardiac function in mice with hypertrophic cardiomyopathy (HCM) and its potential molecular mechanism.Methods·Mice with myosin heavy chain 6 (Myh6) c.1211G>A (p.R404Q+/-) point
Externí odkaz:
https://doaj.org/article/c2eb2c56c9d748c5a8264c9c4f94a788
Publikováno v:
Microorganisms, Vol 12, Iss 7, p 1452 (2024)
Bioethanol fermentation from lignocellulosic hydrolysates is negatively affected by the presence of acetic acid. The budding yeast S. cerevisiae adapts to acetic acid stress partly by activating the transcription factor, Haa1. Haa1 induces the expres
Externí odkaz:
https://doaj.org/article/bbc98850913f4781a8154f06593ede37
Autor:
Analia G. Novero, Catalina Curcio, Tomás J. Steeman, Andres Binolfi, Diego Krapf, Mariano G. Buffone, Dario Krapf, Cintia Stival
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
The cAMP-dependent protein kinase (PKA) is one of the most extensively distributed kinases among intracellular signal cascades, with a pivotal role in the regulation of various processes, including the capacitation of sperm cells. Traditional assessm
Externí odkaz:
https://doaj.org/article/c6f8f492d1dc4b82915273e5633269f8
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Background Chronic hepatitis C virus (HCV) infection causes hepatocellular carcinoma (HCC). The HCC risk, while decreased compared with active HCV infection, persists in HCV-cured patients by direct-acting antiviral agents (DAA). We previous
Externí odkaz:
https://doaj.org/article/4ebdc79139664e46997b83b5df186132
Publikováno v:
European Journal of Cell Biology, Vol 102, Iss 3, Pp 151336- (2023)
Respiratory syncytial virus (RSV) is the leading cause of acute lower respiratory tract infection in infants and young children globally and is responsible for hospitalization and mortality in the elderly population. Virus-induced airway epithelial b
Externí odkaz:
https://doaj.org/article/d514235911f647b681ba9bfcae1cf675
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