Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Protein Bcl-XL"'
Autor:
Faustino, Viviane Dias
As estatísticas relacionadas aos cânceres hematológicos indicam que a incidência e mortalidade dessas doenças têm aumentado ao longo dos anos. Embora a maioria dos casos de linfomas e leucemias não possua etiologia definida, sugere-se que fato
Autor:
Sever, NI, Cengiz Sahin, S
S6K2, the newer member of S6 Kinase family, is a crucial modulator of Akt/mTOR signaling pathway and is a member of AGC kinase family that regulates cellular growth and survival. S6K1 and S6K2 share high sequence similarity; therefore, S6K2 had been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6bdd610e9f074ef94c427ea9faed17f6
Akademický článek
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Novel and combinatorial treatment methods are becoming sought after entities in cancer treatment and these treatments are even more valuable for pancreatic cancer. The scientists are always on the lookout for new chemicals to help them in their fight
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73dae84464d88c2af7195c2db5f386c5
https://doi.org/10.1016/j.gene.2015.10.061
https://doi.org/10.1016/j.gene.2015.10.061
Autor:
Nazan Özsan, Nedim Karagenc, Ender Duzcan, Nilay Şen Türk, Vildan Caner, Mine Hekimgil, Füsun Düzcan
Publikováno v:
Turkish Journal of Hematology, Vol 28, Iss 01, Pp 15-26 (2011)
WOS: 000288828600002
PubMed ID: 27263937
Our aim was to investigate the expression of apoptosis-associated proteins (bcl-2, bcl-xl, bax, bak, bid), apoptotic index (AI) and proliferation index (PI) in germinal center B-cell-like immunopheno
PubMed ID: 27263937
Our aim was to investigate the expression of apoptosis-associated proteins (bcl-2, bcl-xl, bax, bak, bid), apoptotic index (AI) and proliferation index (PI) in germinal center B-cell-like immunopheno
Publikováno v:
Cell Death & Differentiation. 15:1170-1177
Neural tube defects (NTDs), such as spina bifida (SB) or exencephaly, are common congenital malformations leading to infant mortality or severe disability. The etiology of NTDs is multifactorial with a strong genetic component. More than 70 NTD mouse
Autor:
Roberta Cianfrocca, Alessandro Annibaldi, Antonio Costanzo, Michela Muscolini, V Marzano, Barbara Marinari, Massimo Levrero, Loretta Tuosto
Publikováno v:
Cell Death & Differentiation. 15:354-363
The balance between antiapoptotic and proapoptotic proteins of the Bcl-2 family is critical in determining the fate of T cells in response to death stimuli. Proapoptotic genes, such as bax, are generally regulated by the p53 family of transcription f
Autor:
Gulsah Gundogdu, Yusuf Yilmaz, Ismail Yilmaz, Yavuz Dodurga, Vural Kucukatay, Ulker Cankurt, Esat Adiguzel, Ilgaz Akdogan, Seda Ozbal, Goksin Nilufer Yonguc
We aimed to investigate the effects of grape seed extract (GSE) and vitamin E (Vit E) on oxidative stress and apoptosis in the hippocampus of streptozotocin-induced diabetic rats. In Control, Diabetic, and Diabetic treated with GSE (Diabetic + GSE) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe7042e036f1c68ce9806fd066297162
http://acikerisim.pau.edu.tr:8080/xmlui/handle/11499/10468
http://acikerisim.pau.edu.tr:8080/xmlui/handle/11499/10468
Publikováno v:
Biochim. Biophys. Acta Mol. Cell Res. 2006;1763(2):238-246
Biblioteca Digital (UBA-FCEN)
Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales
instacron:UBA-FCEN
Biblioteca Digital (UBA-FCEN)
Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales
instacron:UBA-FCEN
Since apoptosis appeared to be related to neurodegenerative processes, neuroprotection has been involved in investigation of therapeutic approaches focused upon pharmacological agents to prevent neuronal programmed cell death. In this regard, erythro
Autor:
Zsolt Sarang, Susanna Cotecchia, Zsuzsa Szondy, Szabolcs Gomba, Tamás Németh, Tamás Kardon, László Fésüs, Peter Molnar, Gerry Melino
Publikováno v:
Hepatology. 42:578-587
Tissue transglutaminase (TG2) is a protein cross-linking enzyme known to be expressed by hepatocytes and to be induced during the in vivo hepatic apoptosis program. TG2 is also a G protein that mediates intracellular signaling by the alpha-1b-adrener