Zobrazeno 1 - 10
of 306
pro vyhledávání: '"Protegrin"'
Autor:
Alexandr N. Chernov, Tatiana A. Filatenkova, Ruslan I. Glushakov, Alexandra S. Buntovskaya, Diana A. Alaverdian, Anna N. Tsapieva, Alexandr V. Kim, Evgeniy V. Fedorov, Sofia S. Skliar, Marina V. Matsko, Elvira S. Galimova, Olga V. Shamova
Publikováno v:
Molecules, Vol 27, Iss 15, p 4988 (2022)
Glioblastoma (GBM) is one of the most aggressive and lethal malignancy of the central nervous system. Temozolomide is the standard of care for gliomas, frequently results in resistance to drug and tumor recurrence. Therefore, further research is requ
Externí odkaz:
https://doaj.org/article/05e71207e1fe408896a91516887ff597
Akademický článek
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Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Cathelicidins, a class of antimicrobial peptides, have been widely studied for their antimicrobial role in innate immune responses during infection and inflammation. At sub-antimicrobial concentrations, various cathelicidins from different species ha
Externí odkaz:
https://doaj.org/article/7b5a2971c79c45bfa2d6836e1e8ca739
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Protegrin (PG) belongs to the antimicrobial peptide cathelicidin family. To date, five protegrin sequences have been identified in pigs, PG-1 to PG-5. Of these, PG-1 exhibits potent antimicrobial activity against a broad range of antibiotic-resistant
Externí odkaz:
https://doaj.org/article/72a2c76802a4463d982b3ecbcbf37296
Publikováno v:
J Membr Biol
Protegrin-1 (PG-1), an 18-residue β-hairpin stabilized by two disulfide bonds, is a member of a family of powerful antimicrobial peptides which are believed to act through membrane permeabilization. Here we used a combination of experimental and com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50767218c9c5aa0e69b77514ba05f42e
https://doi.org/10.1007/s00232-020-00124-3
https://doi.org/10.1007/s00232-020-00124-3
Akademický článek
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Publikováno v:
International Journal of Peptide Research and Therapeutics. 26:1493-1501
Multi drug resistance is a major problem of the twenty first century. In order to combat this issue, there is an urgent need in the pharmaceutical industry, for novel therapeutic agents. Antimicrobial peptides such as protegrins which exhibit non-spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca7d18fa0731bf2874c6d6dfd472378f
https://doi.org/10.1007/s10989-019-09955-8
https://doi.org/10.1007/s10989-019-09955-8
Autor:
Ju-Young Lee, Chankyu Park, Hyoim Jeon, Min Kyeung Choi, Taehoon Chun, Hyuk Song, Jin-Hoi Kim, Manheum Na, Minh Thong Le, Se Yeoun Cha, Hye Sun Cho
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 1586, p 1586 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 4
International Journal of Molecular Sciences
Volume 22
Issue 4
Antimicrobial peptides (AMPs) are of interest as alternatives to antibiotics or immunomodulators. We generated and characterized the phenotypes of transgenic mice overexpressing protegrin 1 (PG1), a potent porcine cathelicidin. No obvious differences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99fb8d77f363f6591633d56cd50c6991
https://www.mdpi.com/1422-0067/22/4/1586
https://www.mdpi.com/1422-0067/22/4/1586
Autor:
Yiannis N. Kaznessis, Pin-Kuang Lai
Publikováno v:
ACS Omega
ACS Omega, Vol 3, Iss 6, Pp 6056-6065 (2018)
ACS Omega, Vol 3, Iss 6, Pp 6056-6065 (2018)
Protegrin-1 (PG-1) is a cationic arginine-rich antimicrobial peptide. It is widely accepted that PG-1 induces membrane disruption by forming pores that lead to cell death. However, the insertion mechanism for these highly cationic peptides into the h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf746e28edcf20e4fe8011d4cc47a04a
https://doi.org/10.1021/acsomega.8b00483
https://doi.org/10.1021/acsomega.8b00483
Autor:
Adrián Gómez-de-Jesús, Norma Janet Valdes-Perez, Juan Antonio Cortes-Ruíz, Ketzasmin Armando Terrón-Mejía, Hebert Jair Barrales-Cureño, Salvador Chávez-Salinas, Luis Germán López-Valdez, César Reyes, Tania Sánchez-Ovando
Publikováno v:
Mexican Journal of Biotechnology. 3:23-42
Se tomaron las secuencias de la indolicidina y protegrina-4 del banco de datos de la Universidad de Nebraska, USA y se mandaron sintetizar a la empresa EZBiolab Co., pero con la peculiaridad de que no cuentan con amidación y acetilación, estos pép
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d813e0173ccb7d6a45c18a7cf2697a0
https://doi.org/10.29267/mxjb.2018.3.1.23
https://doi.org/10.29267/mxjb.2018.3.1.23