Lack of a protective effect of the Tmem106b 'protective SNP' in the Grn knockout mouse model for frontotemporal lobar degeneration

Autor: Anne-Sophie Cabron, Uwe Borgmeyer, Julia Richter, Helga Peisker, Katharina Gutbrod, Peter Dörmann, Anja Capell, Markus Damme

Publikováno v: Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-13 (2023)

Abstract Genetic variants in TMEM106B are a common risk factor for frontotemporal lobar degeneration and the most important modifier of disease risk in patients with progranulin (GRN) mutations (FTLD-GRN). TMEM106B is encoding a lysosomal transmembra

Externí odkaz: https://doaj.org/article/16fa8d32c9a846b2901774631f5e6e59

Adolescent binge drinking disrupts normal trajectories of brain functional organization and personality maturation

Autor: Zhaowen Liu, Herta Flor, Frauke Nees, Gabriel Robert, Christian Büchel, Juliane H. Fröhner, Tobias Banaschewski, Yunyi Zhou, Michael N. Smolka, Sylvane Desrivières, Fei Li, Qiang Luo, Robert Whelan, Andreas Heinz, Arun L.W. Bokde, Gunter Schumann, Luise Poustka, Erin Burke Quinlan, Marie-Laure Paillère Martinot, Henrik Walter, Penny A. Gowland, Vincent Frouin, Jianfeng Feng, Hongtao Ruan, Bernd Ittermann, Hugh Garavan, Jean-Luc Martinot, Dimitri Papadopoulos Orfanos, Uli Bromberg, Sarah Hohmann

Publikováno v: NeuroImage: Clinical, Vol 22, Iss, Pp-(2019)
NeuroImage: Clinical
Neuroimage-Clinical
Neuroimage-Clinical, 2019, 22, pp.101804. ⟨10.1016/j.nicl.2019.101804⟩
Quinlan, E B, Desrivieres, S & Schumann, G 2019, ' Adolescent binge drinking disrupts normal trajectories of brain functionalorganization and personality maturation ', NeuroImage. Clinical, vol. 22, 101804 . https://doi.org/10.1016/j.nicl.2019.101804
NeuroImage : Clinical
Neuroimage-Clinical, Elsevier, 2019, 22, pp.101804. ⟨10.1016/j.nicl.2019.101804⟩

Adolescent binge drinking has been associated with higher risks for the development of many health problems throughout the lifespan. Adolescents undergo multiple changes that involve the co-development processes of brain, personality and behavior; th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5d06f3fbe6e827499264091a816b7b6
http://www.sciencedirect.com/science/article/pii/S2213158219301548