Zobrazeno 1 - 10
of 4 274
pro vyhledávání: '"Proteasome Pathway"'
Autor:
Mamata Chaudhari, Igor Zelko, Pawel Lorkiewicz, David Hoetker, Yibing Nong, Benjamin Doelling, Kenneth Brittian, Aruni Bhatnagar, Sanjay Srivastava, Shahid P. Baba
Publikováno v:
Skeletal Muscle, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Muscle wasting is a serious complication in heart failure patients. Oxidative stress and inflammation are implicated in the pathogenesis of muscle wasting. Oxidative stress leads to the formation of toxic lipid peroxidation products, such as
Externí odkaz:
https://doaj.org/article/e219c85edc9c4286b5285ba0bdfb315e
Autor:
Peilin Ruan, Yalin Chen, Mingshu Wang, Anchun Cheng, Qiao Yang, Bin Tian, Xumin Ou, Di Sun, Yu He, Zhen Wu, Juan Huang, Ying Wu, Shaqiu Zhang, Xinxin Zhao, Dekang Zhu, Renyong Jia, Mafeng Liu, Shun Chen
Publikováno v:
Poultry Science, Vol 103, Iss 12, Pp 104378- (2024)
ABSTRACT: Duck plague virus (DPV), which is the causative agent of duck viral enteritis, is highly infectious and can cause severe disease and death in ducks, geese and other waterfowl. Several tegument proteins of DPV have been shown to affect the c
Externí odkaz:
https://doaj.org/article/f6db01e323504077ac2605f14ed0b6dc
Publikováno v:
Acta Biochimica et Biophysica Sinica, Vol 56, Pp 1425-1436 (2024)
Chikungunya virus (CHIKV) is a neglected arthropod-borne and anthropogenic alphavirus. Over the past two decades, the CHIKV distribution has undergone significant changes worldwide, from the original tropics and subtropics regions to temperate region
Externí odkaz:
https://doaj.org/article/d0812781986847679e76cad43466468b
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Ferroptosis is an emerging mode of programmed cell death fueled by iron buildup and lipid peroxidation. Recent evidence points to the function of ferroptosis in the aetiology and development of cancer and other disorders. Consequently, harnessing iro
Externí odkaz:
https://doaj.org/article/e7a70c265a334d6d95f0312b9f0aeb61
Publikováno v:
Shipin Kexue, Vol 44, Iss 24, Pp 112-117 (2023)
In this study, the Longissimus dorsi muscle of Qinchuan cattle was injected with the proteasome inhibitor MG-132 immediately postmortem and then stored at 4 ℃. The effect of the ubiquitin-proteasome pathway (UPP) on protein degradation as well as c
Externí odkaz:
https://doaj.org/article/8e284ff1b5d24d9b8bd38b02ece8f43f
Autor:
Junjie Sun, Hai Zhou, Zehao Chen, Han Zhang, Yanzhe Cao, Xinlei Yao, Xin Chen, Boya Liu, Zihui Gao, Yuntian Shen, Lei Qi, Hualin Sun
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Background Denervation-induced muscle atrophy is complex disease involving multiple biological processes with unknown mechanisms. N6-methyladenosine (m6A) participates in skeletal muscle physiology by regulating multiple levels of RNA metabo
Externí odkaz:
https://doaj.org/article/957086129a684c0ea737e68638ba0e9f
Autor:
Jiyeun Park, Hyun-Hee Lee, Heeji Moon, Nahyun Lee, Sieun Kim, Jung-Eun Kim, Yoonji Lee, Kyunghun Min, Hun Kim, Gyung Ja Choi, Yin-Won Lee, Young-Su Seo, Hokyoung Son
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 5 (2023)
ABSTRACT In plant-pathogen interactions, oxidative bursts are crucial for plants to defend themselves against pathogen infections. Rapid production and accumulation of reactive oxygen species kill pathogens directly and cause local cell death, preven
Externí odkaz:
https://doaj.org/article/1688442c32674e89913752858b2f176c
Autor:
Liza Ngomdir, V V Bharathwaj, P Nimmy, R Sindhu, Dinesh Dhamodhar, S Sathiyapriya, D Prabu, M RajMohan
Publikováno v:
Journal of Pharmacy and Bioallied Sciences, Vol 15, Iss 5, Pp 738-741 (2023)
Multiple myeloma is a malignant cancerous condition that is characterized by abnormal plasma cell production and can lead to bone destruction due to increased osteoclastic activity and decreased osteoblastic activity. Many therapeutic therapies are u
Externí odkaz:
https://doaj.org/article/b26496a29c834f12be72f90eaac7a5b9
Publikováno v:
Cells, Vol 13, Iss 2, p 175 (2024)
This review explores various methods for modulating protein stability to achieve target protein degradation, which is a crucial aspect in the study of biological processes and drug design. Thirty years have passed since the introduction of heat-induc
Externí odkaz:
https://doaj.org/article/52fcbb25205842af8767eee6fd25bd2e
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