Myocyte-Specific Upregulation of ACE2 in Cardiovascular Disease

Autor: Tucker, N. R., Chaffin, M., Bedi, K. C., Papangeli, I., Akkad, A. -D., Arduini, A., Hayat, S., Eraslan, G., Muus, C., Bhattacharyya, R. P., Stegmann, C. M., HCA Lung network, Zerti, Darin, Margulies, K. B., Ellinor, P. T.

Publikováno v: Circulation
Circulation, American Heart Association, 2020, ⟨10.1161/CIRCULATIONAHA.120.047911⟩
medRxiv
Circulation, 142(7), 708-710. LIPPINCOTT WILLIAMS & WILKINS

Coronavirus disease 2019 (COVID-19) is a global pandemic caused by a novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). SARS-CoV-2 infection of host cells occurs predominantly via binding of the viral surface spike protein to the hum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7b6a7cec4d8aae888fe9662729eb353
https://research.rug.nl/en/publications/3220c8b9-6a61-464a-9f35-591df95ea86c

Transmission of HIV Drug Resistance and the Predicted Effect on Current First-line Regimens in Europe

Autor: Moutschen, M., Hofstra, Laura Marije Arije, Sauvageot, Nicolas, Albert, Jan, Alexiev, Ivailo, Garcia, Federico, Struck, Daniel, Van, de Vijver, Åsjö, Birgitta, Beshkov, Danail, Coughlan, Suzie, Descamps, Diane, Griskevicius, Algirdas, Hamouda, Osamah, Horban, Andrzej, Van Kasteren, Marjo, Kolupajeva, Tatjana, Kostrikis, Leontios G., Liitsola, Kirsi, Linka, Marek, Mor, Orna, Nielsen, Claus, Otelea, Dan, Paraskevis, Dimitrios N., Paredes, Roger, Poljak, Mario, Puchhammer-Stöckl, Elisabeth, Sönnerborg, Anders, Staneková, Danica, Stanojevic, Maja, Van Laethem, Kristel, Zazzi, Maurizio, Zidovec Lepej, Snjezana, Boucher, Charles A. B., Schmit, Jean-Claude, Wensing, Annemarie M. J., Puchhammer-Stockl, E., Sarcletti, M., Schmied, B., Geit, M., Balluch, G., Vandamme, A. M., Vercauteren, J., Derdelinckx, I., Sasse, A., Bogaert, M., Ceunen, H., De Roo, A., De Wit, S., Echahidi, F., Fransen, K., Goffard, J. -C, Goubau, P., Goudeseune, E., Yombi, J. -C, Lacor, P., Liesnard, C., Pierard, D., Rens, R., Schrooten, Y., Vaira, D., Vandekerckhove, L. P. R., Van, den Heuvel, Van, Der Gucht, Van Ranst, M., Van Wijngaerden, E., Vandercam, B., Vekemans, M., Verhofstede, C., Clumeck, N., Van Laethem, K., Lepej, S. Z., Begovac, J., Demetriades, Ioannis, Kousiappa, Ioanna, Demetriou, Victoria L., Hezka, Johana, Linka, M., Maly, M., Machala, L., Nielsen, C., Jørgensen, L. B., Gerstoft, J., Mathiesen, L., Pedersen, C., Nielsen, H., Laursen, A., Kvinesdal, B., Liitsola, K., Ristola, M., Suni, J., Sutinen, J., Descamps, D., Assoumou, L., Castor, G., Grude, M., Flandre, P., Storto, A., Hamouda, O., Kücherer, C., Berg, T., Braun, P., Poggensee, G., Däumer, M., Eberle, J., Heiken, H., Kaiser, R., Knechten, H., Korn, K., Müller, H., Neifer, S., Schmidt, B., Walter, H., Gunsenheimer-Bartmeyer, B., Harrer, T., Hatzakis, Angelos E., Zavitsanou, Assimina, Vassilakis, A., Lazanas, Marios C., Chini, Maria C., Lioni, A., Sakka, V., Kourkounti, Sofia, Paparizos, Vassilios A., Antoniadou, Anastasia C., Papadopoulos, Antonios I., Poulakou, Garyphallia G., Katsarolis, I., Protopapas, K., Chryssos, Georgios, Drimis, Stylianos, Gargalianos, Panagiotis, Xylomenos, Georgios, Lourida, G., Psichogiou, Mina A., Daikos, George L., Sipsas, N. V., Kontos, Athanasios N., Gamaletsou, M. N., Koratzanis, Georgios, Sambatakou, H., Mariolis, H., Skoutelis, A., Papastamopoulos, V., Georgiou, O., Panagopoulos, Periklis, Maltezos, E., Coughlan, S., De Gascun, C., Byrne, C., Duffy, M., Bergin, C., Reidy, D., Farrell, G., Lambert, J., O'Connor, E., Rochford, A., Low, J., Coakely, P., O'Dea, S., Hall, W., Mor, O., Levi, I., Chemtob, D., Grossman, Z., Zazzi, M., de Luca, A., Balotta, Claudia, Riva, C., Mussini, C., Caramma, I., Capetti, A., Colombo, M. C., Rossi, C., Prati, F., Tramuto, F., Vitale, F., Ciccozzi, M., Angarano, G., Rezza, G., Kolupajeva, T., Vasins, O., Griskevicius, A., Lipnickiene, V., Schmit, J. C., Struck, D., Hemmer, R., Arendt, V., Michaux, C., Staub, T., Sequin-Devaux, C., Wensing, A. M. J., Boucher, C. A. B., van, de Vijver, van Kessel, A., van Bentum, P. H. M., Brinkman, K., Connell, B. J., van, der Ende, Hoepelman, I. M., van Kasteren, M., Kuipers, M., Langebeek, N., Richter, C., Santegoets, R. M. W. J., Schrijnders-Gudde, L., Schuurman, R., van, de Ven, Kran, A. -M B., Ormaasen, V., Aavitsland, P., Horban, A., Stanczak, J. J., Stanczak, G. P., Firlag-Burkacka, E., Wiercinska-Drapalo, A., Jablonowska, E., Maolepsza, E., Leszczyszyn-Pynka, M., Szata, W., Camacho, Ricardo J., Palma, C., Borges, F., Paixão, T., Duque, V., Araújo, F., Otelea, D., Paraschiv, S., Tudor, A. M., Cernat, R., Chiriac, C., Dumitrescu, F., Prisecariu, L. J., Stanojevic, M., Jevtovic, Dj, Salemovic, D., Stanekova, D., Habekova, M., Chabadová, Z., Drobkova, T., Bukovinova, P., Shunnar, A., Truska, P., Poljak, M., Lunar, M., Babic, Dunja Z., Tomazic, J., Vidmar, L., Vovko, T., Karner, P., Garcia, F., Paredes, R., Monge, S., Moreno, S., del Amo, J., Asensi, V., Sirvent, J. L., de Mendoza, C., Delgado, R., Gutiérrez, F., Berenguer, J., Garcia-Bujalance, S., Stella, Natalia C., de, los Santos, Blanco, J. R., Dalmau, D., Rivero, M., Segura, F., Elıás, Marıá Jesús Pérez, Alvarez, M., Chueca, N., Rodríguez-Martín, C., Vidal, C., Palomares, J. C., Viciana, I., Viciana, P., Cordoba, J., Aguilera, A., Domingo, P., Galindo, M. J., Miralles, C., del Pozo, M. A., Ribera, E., Iribarren, J. A., Ruiz, L., de, la Torre, Vidal, F., Clotet, B., Heidarian, A., Aperia-Peipke, K., Axelsson, M., Mild, M., Karlsson, A., Sönnerborg, A., Thalme, A., Navér, L., Bratt, G., Blaxhult, A., Gisslén, M., Svennerholm, B., Bergbrant, I., Björkman, Per, Säll, C., Mellgren, Å., Lindholm, A., Kuylenstierna, N., Montelius, R., Azimi, F., Johansson, B., Carlsson, M., Johansson, E., Ljungberg, B., Ekvall, H., Strand, A., Mäkitalo, S., Öberg, S., Holmblad, P., Höfer, M., Holmberg, H., Josefson, P., Ryding, U., Van Kessel, A.

Publikováno v: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
CLINICAL INFECTIOUS DISEASES
Clinical Infectious Diseases, 62(5), 655-663. Oxford University Press
Clinical infectious diseases, 62(5), 655-663. Oxford University Press
Clinical Infectious Diseases
Clin.Infect.Dis.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
Hofstra, L M, Sauvageot, N, Albert, J, Alexiev, I, Garcia, F, Struck, D, Van de Vijver, D A M C, Åsjö, B, Beshkov, D, Coughlan, S, Descamps, D, Griskevicius, A, Hamouda, O, Horban, A, Van Kasteren, M, Kolupajeva, T, Kostrikis, L G, Liitsola, K, Linka, M, Mor, O, Nielsen, C, Otelea, D, Paraskevis, D, Paredes, R, Poljak, M, Puchhammer-Stöckl, E, Sönnerborg, A, Staneková, D, Stanojevic, M, Van Laethem, K, Zazzi, M, Zidovec Lepej, S, Boucher, C A B, Schmit, J-C, Wensing, A M J & SPREAD Program 2016, ' Transmission of HIV Drug Resistance and the Predicted Effect on Current First-line Regimens in Europe ', Clinical Infectious Diseases, vol. 62, no. 5, pp. 655-663 . https://doi.org/10.1093/cid/civ963
Clinical Infectious Diseases, 62(5), 655. Oxford University Press

Transmitted human immunodeficiency virus drug resistance in Europe is stable at around 8%. The impact of baseline mutation patterns on susceptibility to antiretroviral drugs should be addressed using clinical guidelines. The impact on baseline suscep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41b36da0d354012c11ec6a9ed8516493
http://hdl.handle.net/11365/995728

Cellular and viral Fos proteins are degraded by different proteolytic systems

Autor: Frédérique Brockly, Guillaume Bossis, Claire Acquaviva, Marc Piechaczyk, Isabelle Jariel-Encontre, Patrizia Ferrara, Cathy Salvat

Publikováno v: Oncogene
Oncogene, Nature Publishing Group, 2001, 20 (8), pp.942--50. ⟨10.1038/sj.onc.1204155⟩

c-Fos proto-oncoprotein is a short-lived transcription factor degraded by the proteasome in vivo. Its mutated forms expressed by the mouse osteosarcomatogenic retroviruses, FBJ-MSV and FBR-MSV, are stabilized two- and threefold, respectively. To eluc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de393f68d3bab7c8d37d844a08ca5129
https://doi.org/10.1038/sj.onc.1204155

The plasticity of the β-trefoil fold constitutes an evolutionary platform for protease inhibition

Autor: Danielle Baeyens-Volant, Mohamed Azarkan, Abel Garcia-Pino, Lieven Buts, Sergio Martínez-Rodríguez

Publikováno v: The Journal of biological chemistry, 286 (51

Proteases carry out a number of crucial functions inside and outside the cell. To protect the cells against the potentially lethal activities of these enzymes, specific inhibitors are produced to tightly regulate the protease activity. Independent re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0a50f3f4864fa7b74bbac900efbd1ab
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/110371

Activation and enzymatic characterization of recombinant human kallikrein 8

Autor: Eleftherios P. Diamandis, David Deperthes, Tadaaki Kishi, Christoph Kündig, Cloutier Sylvain

Publikováno v: Biological chemistry, vol. 387, no. 6, pp. 723-731

Human kallikrein 8 (hK8), whose gene was originally cloned as the human ortholog of a mouse brain protease, is known to be associated with diseases such as ovarian cancer and Alzheimer's disease. Recombinant human pro-kallikrein 8 was activated with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5145e174c7f9041e5e80832757fe6dc2
https://doi.org/10.1515/bc.2006.091