Prion protein oligomers cause neuronal cytoskeletal damage in rapidly progressive Alzheimer’s disease

Autor: Berta Puig, Jakob Matschke, Mohsin Shafiq, Neelam Younas, Markus Glatzel, Matthias Schmitz, Aneeqa Noor, Isidre Ferrer, Hermann C. Altmeppen, Saima Zafar, Inga Zerr

Publikováno v: Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-14 (2021)
Dipòsit Digital de la UB
Universidad de Barcelona
Molecular Neurodegeneration
Molecular neurodegeneration 16(1), 11 (2021). doi:10.1186/s13024-021-00422-x

Background High-density oligomers of the prion protein (HDPs) have previously been identified in brain tissues of patients with rapidly progressive Alzheimer’s disease (rpAD). The current investigation aims at identifying interacting partners of HD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8bb5ec7f75f2f6ab829e32422cc6b2e
https://doaj.org/article/7c71674b4d0c4550b9d3d91ece6ae9d5

NatB-mediated protein N-α-terminal acetylation is a potential therapeutic target in hepatocellular carcinoma

Autor: Pere Roca-Cusachs, Sara Alve, Marta Lasa, Bruno Sangro, José Ignacio Herrero, Alberto Elosegui-Artola, Leire Neri, Cristina Gazquez, Delia D'Avola, Beatriz Carte, Mercedes Iñarrairaegui, Rafael Aldabe, Jesús Prieto

Publikováno v: Oncotarget
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname

// Leire Neri 1 , Marta Lasa 1 , Alberto Elosegui-Artola 2 , Delia D'Avola 3, 4 , Beatriz Carte 1 , Cristina Gazquez 1 , Sara Alve 5 , Pere Roca-Cusachs 2, 6 , Mercedes Inarrairaegui 3, 4 , Jose Herrero 3, 4 , Jesus Prieto 1, 3 , Bruno Sangro 3, 4 an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0bbb973d3efa8b5cd1ebe14c1095682
https://doi.org/10.18632/oncotarget.17332

The Stress-Inducible Protein DRR1 Exerts Distinct Effects on Actin Dynamics

Autor: Jan-Philip Schülke, Marianne B. Müller, Andreas R. Bausch, Mercè Masana, Theo Rein, Katharina Dürre, Anja Kretzschmar

Publikováno v: International Journal of Molecular Sciences
Dipòsit Digital de la UB
Universidad de Barcelona
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
International Journal of Molecular Sciences, Vol 19, Iss 12, p 3993 (2018)
Recercat. Dipósit de la Recerca de Catalunya
instname
Volume 19
Issue 12

Cytoskeletal dynamics are pivotal to memory, learning, and stress physiology, and thus psychiatric diseases. Downregulated in renal cell carcinoma 1 (DRR1) protein was characterized as the link between stress, actin dynamics, neuronal function, and c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f4dbc5a4e41aab7127a572db065bc4a
https://pubmed.ncbi.nlm.nih.gov/30545002

Membrane tension controls adhesion positioning at the leading edge of cells

Autor: Anabel-Lise Le Roux, Lisa Tucker-Kellogg, Sophie Kan, Bruno Pontes, Virgile Viasnoff, Laurent Gole, Pere Roca-Cusachs, Anita Joanna Kosmalska, Pascale Monzo, Zhi Yang Tam, Weiwei Luo, Nils C. Gauthier

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
The Journal of Cell Biology
Recercat. Dipósit de la Recerca de Catalunya
instname

Pontes et al. show that plasma membrane mechanics exerts an upstream control during cell motility. Variations in plasma membrane tension orchestrate the behavior of the cell leading edge, with increase–decrease cycles in tension promoting adhesion

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8d39bab48bd9492af9aafd43c17e752
http://hdl.handle.net/2445/123547

α-Actinin links extracellular matrix rigidity-sensing contractile units with periodic cell-edge retractions

Autor: James Lohner, Giovanni Meacci, Alexander Gondarenko, James Hone, Matthew R. Stachowiak, Anurag Mathur, Ben O'Shaughnessy, Thomas Iskratsch, Shuaimin Liu, Haguy Wolfenson, Nils C. Gauthier, Saba Ghassemi, Erdem Tabdanov, Ashok C. Chander, Pere Roca-Cusachs, Michael P. Sheetz

Publikováno v: Recercat. Dipósit de la Recerca de Catalunya
instname
Molecular Biology of the Cell
Meacci, G, Wolfenson, H, Liu, S, Stachowiak, M R, Iskratsch, T, Mathur, A, Ghassemi, S, Gauthier, N, Tabdanov, E, Lohner, J, Gondarenko, A, Chander, A C, Roca-Cusachs, P, O'Shaughnessy, B, Hone, J & Sheetz, M P 2016, ' α-Actinin links extracellular matrix rigidity-sensing contractile units with periodic cell-edge retractions ', Molecular biology of the cell, vol. 27, no. 22, pp. 3471-3479 . https://doi.org/10.1091/mbc.E16-02-0107, https://doi.org/10.1091/mbc.E16-02-0107
Dipòsit Digital de la UB
Universidad de Barcelona

During cell migration, the cell edge undergoes periodic protrusion–retraction cycles. Quantitative analyses of the forces at the cell edge that drive these cycles are provided. We show that α-actinin links local contractile units and the global ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac3484a52694fe4a7d98f1e08c5d2dbe
http://hdl.handle.net/2445/109187