Zobrazeno 1 - 10
of 682
pro vyhledávání: '"Prota AE"'
Autor:
Dessin C; Bielefeld University, Chemistry, GERMANY., Schachtsiek T; Bielefeld University, Chemistry, GERMANY., Voss J; Bielefeld University, Chemistry, GERMANY., Abel AC; Paul Scherrer Institute, Laboratory of Biomolecular Research, Center for Life Sciences, SWITZERLAND., Neumann B; Bielefeld University, Chemistry, GERMANY., Stammler HG; Bielefeld University, Chemistry, GERMANY., Prota AE; Paul Scherrer Institute, Laboratory of Biomolecular Research, Center for Life Sciences, SWITZERLAND., Sewald N; University of Bielefeld, Chemistry, PO Box 100131, 33501, Bielefeld, GERMANY.
Publikováno v:
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2024 Sep 26, pp. e202416210. Date of Electronic Publication: 2024 Sep 26.
Autor:
Steinmetz MO; Laboratory of Biomolecular Research, Division of Biology and Chemistry, Paul Scherrer Institut, CH-5232 Villigen PSI, Switzerland; University of Basel, Biozentrum, 4056 Basel, Switzerland. Electronic address: michel.steinmetz@psi.ch., Prota AE; Laboratory of Biomolecular Research, Division of Biology and Chemistry, Paul Scherrer Institut, CH-5232 Villigen PSI, Switzerland. Electronic address: andrea.prota@psi.ch.
Publikováno v:
Current opinion in structural biology [Curr Opin Struct Biol] 2024 Aug; Vol. 87, pp. 102845. Date of Electronic Publication: 2024 May 27.
Autor:
Abel AC; Laboratory of Biomolecular Research, Department of Biology and Chemistry, Paul Scherrer Institute, Villigen, Switzerland; Biozentrum, University of Basel, Basel, Switzerland., Mühlethaler T; Biozentrum, University of Basel, Basel, Switzerland., Dessin C; Organic and Bioorganic Chemistry, Department of Chemistry, Bielefeld University, Bielefeld, Germany., Schachtsiek T; Organic and Bioorganic Chemistry, Department of Chemistry, Bielefeld University, Bielefeld, Germany., Sammet B; Organic and Bioorganic Chemistry, Department of Chemistry, Bielefeld University, Bielefeld, Germany., Sharpe T; Biozentrum, University of Basel, Basel, Switzerland., Steinmetz MO; Laboratory of Biomolecular Research, Department of Biology and Chemistry, Paul Scherrer Institute, Villigen, Switzerland; Biozentrum, University of Basel, Basel, Switzerland., Sewald N; Organic and Bioorganic Chemistry, Department of Chemistry, Bielefeld University, Bielefeld, Germany. Electronic address: norbert.sewald@uni-bielefeld.de., Prota AE; Laboratory of Biomolecular Research, Department of Biology and Chemistry, Paul Scherrer Institute, Villigen, Switzerland. Electronic address: andrea.prota@psi.ch.
Publikováno v:
The Journal of biological chemistry [J Biol Chem] 2024 Jun; Vol. 300 (6), pp. 107363. Date of Electronic Publication: 2024 May 10.
Autor:
Homer JA; Cancer Center, Cold Spring Harbor Laboratory 1 Bungtown Rd Cold Spring Harbor NY 11724 USA moses@cshl.edu., Koelln RA; Cancer Center, Cold Spring Harbor Laboratory 1 Bungtown Rd Cold Spring Harbor NY 11724 USA moses@cshl.edu., Barrow AS; La Trobe Institute for Molecular Science, La Trobe University Melbourne VIC 3086 Australia., Gialelis TL; La Trobe Institute for Molecular Science, La Trobe University Melbourne VIC 3086 Australia., Boiarska Z; Laboratory of Biomolecular Research, Division of Biology and Chemistry, Paul Scherrer Institut Villigen PSI 5232 Switzerland.; Department of Chemistry, Università degli Studi di Milano Via Golgi 19 20133 Milan Italy., Steinohrt NS; Olivia Newton-John Cancer Research Institute Heidelberg Victoria 3084 Australia.; School of Cancer Medicine, La Trobe University Melbourne Victoria 3086 Australia., Lee EF; Olivia Newton-John Cancer Research Institute Heidelberg Victoria 3084 Australia.; School of Cancer Medicine, La Trobe University Melbourne Victoria 3086 Australia.; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University Melbourne Victoria 3086 Australia., Yang WH; Cancer Center, Cold Spring Harbor Laboratory 1 Bungtown Rd Cold Spring Harbor NY 11724 USA moses@cshl.edu., Johnson RM; Cancer Center, Cold Spring Harbor Laboratory 1 Bungtown Rd Cold Spring Harbor NY 11724 USA moses@cshl.edu., Chung T; Cancer Center, Cold Spring Harbor Laboratory 1 Bungtown Rd Cold Spring Harbor NY 11724 USA moses@cshl.edu., Habowski AN; Cancer Center, Cold Spring Harbor Laboratory 1 Bungtown Rd Cold Spring Harbor NY 11724 USA moses@cshl.edu., Vishwakarma DS; Cancer Center, Cold Spring Harbor Laboratory 1 Bungtown Rd Cold Spring Harbor NY 11724 USA moses@cshl.edu., Bhunia D; Cancer Center, Cold Spring Harbor Laboratory 1 Bungtown Rd Cold Spring Harbor NY 11724 USA moses@cshl.edu., Avanzi C; Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University Fort Collins CO 80523 USA., Moorhouse AD; Cancer Center, Cold Spring Harbor Laboratory 1 Bungtown Rd Cold Spring Harbor NY 11724 USA moses@cshl.edu., Jackson M; Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University Fort Collins CO 80523 USA., Tuveson DA; Cancer Center, Cold Spring Harbor Laboratory 1 Bungtown Rd Cold Spring Harbor NY 11724 USA moses@cshl.edu., Lyons SK; Cancer Center, Cold Spring Harbor Laboratory 1 Bungtown Rd Cold Spring Harbor NY 11724 USA moses@cshl.edu., Lukey MJ; Cancer Center, Cold Spring Harbor Laboratory 1 Bungtown Rd Cold Spring Harbor NY 11724 USA moses@cshl.edu., Fairlie WD; Olivia Newton-John Cancer Research Institute Heidelberg Victoria 3084 Australia.; School of Cancer Medicine, La Trobe University Melbourne Victoria 3086 Australia.; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University Melbourne Victoria 3086 Australia., Haider SM; School of Pharmacy, University College London 29-39 Brunswick Square London WC1N 1AX UK., Steinmetz MO; Laboratory of Biomolecular Research, Division of Biology and Chemistry, Paul Scherrer Institut Villigen PSI 5232 Switzerland.; Biozentrum, University of Basel 4056 Basel Switzerland., Prota AE; Laboratory of Biomolecular Research, Division of Biology and Chemistry, Paul Scherrer Institut Villigen PSI 5232 Switzerland., Moses JE; Cancer Center, Cold Spring Harbor Laboratory 1 Bungtown Rd Cold Spring Harbor NY 11724 USA moses@cshl.edu.
Publikováno v:
Chemical science [Chem Sci] 2024 Mar 04; Vol. 15 (11), pp. 3879-3892. Date of Electronic Publication: 2024 Mar 04 (Print Publication: 2024).
Autor:
Mühlethaler T; Laboratory of Biomolecular Research, Division of Biology and Chemistry, Paul Scherrer Institut, Villigen PSI, Switzerland., Olieric N; Laboratory of Biomolecular Research, Division of Biology and Chemistry, Paul Scherrer Institut, Villigen PSI, Switzerland., Ehrhard VA; Laboratory of Biomolecular Research, Division of Biology and Chemistry, Paul Scherrer Institut, Villigen PSI, Switzerland., Wranik M; Laboratory of Biomolecular Research, Division of Biology and Chemistry, Paul Scherrer Institut, Villigen PSI, Switzerland., Standfuss J; Laboratory of Biomolecular Research, Division of Biology and Chemistry, Paul Scherrer Institut, Villigen PSI, Switzerland., Sharma A; Laboratory of Biomolecular Research, Division of Biology and Chemistry, Paul Scherrer Institut, Villigen PSI, Switzerland., Prota AE; Laboratory of Biomolecular Research, Division of Biology and Chemistry, Paul Scherrer Institut, Villigen PSI, Switzerland., Steinmetz MO; Laboratory of Biomolecular Research, Division of Biology and Chemistry, Paul Scherrer Institut, Villigen PSI, Switzerland. michel.steinmetz@psi.ch.; University of Basel, Biozentrum, Basel, Switzerland. michel.steinmetz@psi.ch.
Publikováno v:
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2022; Vol. 2430, pp. 349-374.
Autor:
Prota AE; Laboratory of Biomolecular Research, Division of Biology and Chemistry, Paul Scherrer Institute, Villigen PSI, Switzerland., Lucena-Agell D; Centro de Investigaciones Biológicas Margarita Salas, Consejo Superior de Investigaciones Científicas, Madrid, Spain., Ma Y; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Estevez-Gallego J; Centro de Investigaciones Biológicas Margarita Salas, Consejo Superior de Investigaciones Científicas, Madrid, Spain., Li S; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Bargsten K; Laboratory of Biomolecular Research, Division of Biology and Chemistry, Paul Scherrer Institute, Villigen PSI, Switzerland., Josa-Prado F; Centro de Investigaciones Biológicas Margarita Salas, Consejo Superior de Investigaciones Científicas, Madrid, Spain., Altmann KH; Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zurich, Zürich, Switzerland., Gaillard N; Laboratory of Biomolecular Research, Division of Biology and Chemistry, Paul Scherrer Institute, Villigen PSI, Switzerland., Kamimura S; Department of Biological Sciences, Faculty of Science and Engineering, Chuo University, Tokyo, Japan., Mühlethaler T; Laboratory of Biomolecular Research, Division of Biology and Chemistry, Paul Scherrer Institute, Villigen PSI, Switzerland., Gago F; Department of Biomedical Sciences, University of Alcalá, Madrid, Spain., Oliva MA; Centro de Investigaciones Biológicas Margarita Salas, Consejo Superior de Investigaciones Científicas, Madrid, Spain., Steinmetz MO; Laboratory of Biomolecular Research, Division of Biology and Chemistry, Paul Scherrer Institute, Villigen PSI, Switzerland.; University of Basel, Basel, Switzerland., Fang WS; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Díaz JF; Centro de Investigaciones Biológicas Margarita Salas, Consejo Superior de Investigaciones Científicas, Madrid, Spain.
Publikováno v:
ELife [Elife] 2023 Mar 06; Vol. 12. Date of Electronic Publication: 2023 Mar 06.
Autor:
Oliva MA, Prota AE, Rodríguez-Salarichs J, Gu W, Bennani YL, Jimenez-Barbero J, Bargsten K, Canales A, Steinmetz MO, Diaz JF
Noscapineisanaturalalkaloidthatisusedasanantitussivemedicine.However,italsoactsasaweakanticanceragentincertaininvivomodelsthroughamechanismthatislargelyunknown.Here,weperformedstructuralstudiesandshowthatthecytotoxicagent7A-O-demethoxy-amino-noscapin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2659::70cbf6f88aab9ede6980ce3afa96a271
https://zenodo.org/record/4309540
https://zenodo.org/record/4309540
Autor:
Pérez-Peña H; Department of Chemistry, Università degli Studi di Milano, Via Golgi 19, 20133 Milan, Italy.; Laboratory of Chemoinformatics, Faculty of Chemistry, University of Strasbourg, 4, Rue Blaise Pascal, 67081 Strasbourg, France., Abel AC; Department of Chemistry, Università degli Studi di Milano, Via Golgi 19, 20133 Milan, Italy.; Laboratory of Biomolecular Research, Paul Scherrer Institute, Forschungsstrasse 111, 5232 Villigen, Switzerland., Shevelev M; Laboratory of Chemoinformatics, Faculty of Chemistry, University of Strasbourg, 4, Rue Blaise Pascal, 67081 Strasbourg, France.; Department of Biochemistry and Molecular Biology, Universitat de Barcelona, Gran Via de les Corts Catalanes, 585, 08007 Barcelona, Spain., Prota AE; Laboratory of Biomolecular Research, Paul Scherrer Institute, Forschungsstrasse 111, 5232 Villigen, Switzerland., Pieraccini S; Department of Chemistry, Università degli Studi di Milano, Via Golgi 19, 20133 Milan, Italy., Horvath D; Laboratory of Chemoinformatics, Faculty of Chemistry, University of Strasbourg, 4, Rue Blaise Pascal, 67081 Strasbourg, France.
Publikováno v:
Biomolecules [Biomolecules] 2023 Feb 02; Vol. 13 (2). Date of Electronic Publication: 2023 Feb 02.
Autor:
Boiarska Z; Department of Chemistry, Università degli Studi di Milano, Via Golgi 19, 20133, Milan, Italy., Pérez-Peña H; Department of Chemistry, Università degli Studi di Milano, Via Golgi 19, 20133, Milan, Italy., Abel AC; Laboratory of Biomolecular Research, Paul Scherrer Institute, Forschungsstrasse 111, 5232, Villigen PSI, Switzerland., Marzullo P; Department of Chemistry, Università degli Studi di Milano, Via Golgi 19, 20133, Milan, Italy., Álvarez-Bernad B; Centro de Investigaciones Biológicas Margarita Salas, Consejo Superior de Investigaciones Científicas Ramiro de Maeztu 9, 28040, Madrid, Spain., Bonato F; Centro de Investigaciones Biológicas Margarita Salas, Consejo Superior de Investigaciones Científicas Ramiro de Maeztu 9, 28040, Madrid, Spain., Santini B; Department of Chemistry, Università degli Studi di Milano, Via Golgi 19, 20133, Milan, Italy., Horvath D; Laboratory of Chemoinformatics, Faculty of Chemistry, University of Strasbourg, rue B. Pascal, 67081, Strasbourg, France., Lucena-Agell D; Centro de Investigaciones Biológicas Margarita Salas, Consejo Superior de Investigaciones Científicas Ramiro de Maeztu 9, 28040, Madrid, Spain., Vasile F; Department of Chemistry, Università degli Studi di Milano, Via Golgi 19, 20133, Milan, Italy., Sironi M; Department of Chemistry, Università degli Studi di Milano, Via Golgi 19, 20133, Milan, Italy., Díaz JF; Centro de Investigaciones Biológicas Margarita Salas, Consejo Superior de Investigaciones Científicas Ramiro de Maeztu 9, 28040, Madrid, Spain., Prota AE; Laboratory of Biomolecular Research, Paul Scherrer Institute, Forschungsstrasse 111, 5232, Villigen PSI, Switzerland., Pieraccini S; Department of Chemistry, Università degli Studi di Milano, Via Golgi 19, 20133, Milan, Italy., Passarella D; Department of Chemistry, Università degli Studi di Milano, Via Golgi 19, 20133, Milan, Italy.
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2023 Jan 24; Vol. 29 (5), pp. e202300069.
Autor:
Estévez-Gallego J; Centro de Investigaciones Biológicas Margarita Salas - Consejo Superior de Investigaciones Científicas, Madrid 28040, Spain., Álvarez-Bernad B; Centro de Investigaciones Biológicas Margarita Salas - Consejo Superior de Investigaciones Científicas, Madrid 28040, Spain., Pera B; Centro de Investigaciones Biológicas Margarita Salas - Consejo Superior de Investigaciones Científicas, Madrid 28040, Spain., Wullschleger C; Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences - ETH Zurich, Zürich 8093, Switzerland., Raes O; Department of Organic and Macromolecular Chemistry, Ghent University, Gent 9000, Belgium., Menche D; Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK., Martínez JC; ALBA Synchrotron, CELLS, Cerdanyola del Vallés 08290, Spain., Lucena-Agell D; Centro de Investigaciones Biológicas Margarita Salas - Consejo Superior de Investigaciones Científicas, Madrid 28040, Spain., Prota AE; Laboratory of Biomolecular Research, Division of Biology and Chemistry, Paul Scherrer Institut, Villigen 5232, Switzerland., Bonato F; Centro de Investigaciones Biológicas Margarita Salas - Consejo Superior de Investigaciones Científicas, Madrid 28040, Spain., Bargsten K; Laboratory of Biomolecular Research, Division of Biology and Chemistry, Paul Scherrer Institut, Villigen 5232, Switzerland., Cornelus J; Department of Organic and Macromolecular Chemistry, Ghent University, Gent 9000, Belgium., Giménez-Abián JF; Centro de Investigaciones Biológicas Margarita Salas - Consejo Superior de Investigaciones Científicas, Madrid 28040, Spain., Northcote P; Ferrier Research Institute, University of Wellington, Lower Hutt 5010, New Zealand., Steinmetz MO; Laboratory of Biomolecular Research, Division of Biology and Chemistry, Paul Scherrer Institut, Villigen 5232, Switzerland; University of Basel, Biozentrum, Basel 4056, Switzerland., Kamimura S; Department of Biological Sciences, Faculty of Science and Engineering, Chuo University, Tokyo 192-0393, Japan., Altmann KH; Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences - ETH Zurich, Zürich 8093, Switzerland., Paterson I; Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK., Gago F; Department of Biomedical Sciences and Associated Unit IQM-UAH, Universidad de Alcalá, Alcalá de Henares 28805, Spain., Van der Eycken J; Department of Organic and Macromolecular Chemistry, Ghent University, Gent 9000, Belgium., Díaz JF; Centro de Investigaciones Biológicas Margarita Salas - Consejo Superior de Investigaciones Científicas, Madrid 28040, Spain., Oliva MÁ; Centro de Investigaciones Biológicas Margarita Salas - Consejo Superior de Investigaciones Científicas, Madrid 28040, Spain. Electronic address: marian@cib.csic.es.
Publikováno v:
Structure (London, England : 1993) [Structure] 2023 Jan 05; Vol. 31 (1), pp. 88-99.e5. Date of Electronic Publication: 2022 Dec 02.