Étude de l'interactome et identification de nouvelles cibles de la protéine virale Vpr du VIH-1

Autor: Ferreira Barbosa, Jérémy A.

Le virus de l’immunodéficience humaine de type 1 (VIH-1) est l’agent étiologique du SIDA, un rétrovirus complexe encodant les protéines accessoires : Nef, Vif, Vpr et Vpu. La fonction principale de ces protéines est de moduler l’environnem

Externí odkaz: http://hdl.handle.net/1866/24609

Investigating the role of intrinsic conformational disorder in mumps virus proteins

Autor: Ivashchenko, Stefaniia

Publikováno v: Virology. Université Grenoble Alpes, 2019. English. ⟨NNT : 2019GREAY026⟩

Mumps is a highly contagious disease caused by the mumps virus. The prevention treatment (vaccine) against it is already in the routine use. However, recent outbreaks still remain uncontrollable. Therefore, it is important to understand the molecular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5b9e37332a4a2a0d037cc4a72b99789a
https://theses.hal.science/tel-02448300

First experimental assessment of protein intrinsic disorder involvement in an RNA virus natural adaptive process

Autor: Eugénie Hébrard, Amandine Barra, Benoît Moury, Justine Charon, Jocelyne Walter, Pauline Millot, Thierry Michon

Publikováno v: Molecular Biology and Evolution 1 (35), 38-49. (2018)
Molecular Biology and Evolution
Molecular Biology and Evolution, Oxford University Press (OUP), 2018, 35 (1), pp.38-49. ⟨10.1093/molbev/msx249⟩
Molecular Biology and Evolution, 2018, 35 (1), pp.38-49. ⟨10.1093/molbev/msx249⟩
Molecular Biology and Evolution, Oxford University Press (OUP), 2017, ⟨10.1093/molbev/msx249⟩

Intrinsic disorder (ID) in proteins is defined as a lack of stable structure in physiological conditions. Intrinsically disordered regions (IDRs) are highly abundant in some RNA virus proteomes. Low topological constraints exerted on IDRs are expecte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d46dc859703d3cacbc43f82848a97f5
http://prodinra.inra.fr/record/410152

Current Advances in Serological Diagnosis of Peste des Petits Ruminants Virus

Autor: Geneviève Libeau

Publikováno v: Peste des Petits Ruminants Virus ISBN: 9783662451649
Peste des petits ruminants virus

Peste des petits ruminants (PPR) is a contagious disease with potential for high economic impacts. Convalescent and vaccinated small ruminants develop a strong and lifelong immunity and are fully protected against re-infection. Consequently, the pres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::234f3e313541413484ff053a56828d50
https://doi.org/10.1007/978-3-662-45165-6_8

[Targeting of PP2A enzymes by viral proteins and cancer signalling]

Autor: Pierre-Barthélémy Falanga, Jean-Hervé Colle, Alphonse Garcia, Xavier Cayla, Amandine Galioot, Julien Guergnon, Angélique N. Godet

Publikováno v: médecine/sciences
médecine/sciences, 2011, 27 (12), pp.1106-11. ⟨10.1051/medsci/20112712017⟩
M/S Médecine/Sciences 12 (27), 1106-1111. (2011)
médecine/sciences, EDP Sciences, 2011, 27 (12), pp.1106-11. ⟨10.1051/medsci/20112712017⟩

Protein phosphatase 2A (PP2A) is a large family of holoenzymes that comprises 1% of total cellular proteins and accounts for the majority of Ser/Thr phosphatase activity in eukaryotic cells. PP2A proteins are made of a core dimer, composed of a catal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9192fbf1f9ecf89c95317c15af97d87a
https://hal.science/hal-01129689/file/medsci20112712p1106.pdf