Polygenic hazard score to guide screening for aggressive - prostate cancer: development and validation in large scale - cohorts

Autor: Ruth C. Travis, Markus Aly, Chun Chieh Fan, Dominika Wokołorczyk, Fredrik Wiklund, Ole A. Andreassen, Børge G. Nordestgaard, Adam S. Kibel, Amanda B. Spurdle, Verena Zuber, Douglas F. Easton, J. Kellogg Parsons, Agnieszka Michael, Lisa A. Cannon-Albright, Judith A. Clements, Cezary Cybulski, Roshan Karunamuni, M. Andreas Røder, Kathleen Herkommer, Vanio Mitev, Zsofia Kote-Jarai, Walther Vogel, Jong Y. Park, Johanna Schleutker, Tyler M. Seibert, Paul D.P. Pharoah, Hermann Brenner, Ian G. Mills, Kai Uwe Saum, Manuel R. Teixeira, Nora Pashayan, Timothy J. Key, Henrik Grönberg, Maren Weischer, Hardev Pandha, Andrzej M. Kierzek, Manuel Luedeke, Rasmus Bisbjerg, Christiane Maier, Freddie C. Hamdy, Katarina Cuk, Sofia Maia, Paula Paulo, Kay-Tee Khaw, Anders M. Dale, Thomas A. Sellers, Csilla Sipeky, Rosalind A. Eeles, Jenny L Donovan, Wojciech Kluzniak, David E. Neal, Yunpeng Wang, David S. Karow, Teuvo L.J. Tammela, Peter Iversen, Chavdar Slavov, Jyotsna Batra, Sune F. Nielsen, Kenneth Muir, Sara Benlloch Garcia, Radka Kaneva, Ali Amin Al Olama

Publikováno v: Seibert, T M, Fan, C C, Wang, Y, Zuber, V, Karunamuni, R, Parsons, J K, Eeles, R A, Easton, D F, Kote-Jarai, ZS, Al Olama, A A, Garcia, S B, Muir, K, Grönberg, H, Wiklund, F, Aly, M, Schleutker, J, Sipeky, C, Tammela, T L, Nordestgaard, B G, Nielsen, S F, Weischer, M, Bisbjerg, R, Røder, M A, Iversen, P, Key, T J, Travis, R C, Neal, D E, Donovan, J L, Hamdy, F C, Pharoah, P, Pashayan, N, Khaw, K-T, Maier, C, Vogel, W, Luedeke, M, Herkommer, K, Kibel, A S, Cybulski, C, Wokolorczyk, D, Kluzniak, W, Cannon-Albright, L, Brenner, H, Cuk, K, Saum, K-U, Park, J Y, Sellers, T A, Slavov, C, Kaneva, R, Mitev, V, Batra, J & PRACTICAL Consortium* 2018, ' Polygenic hazard score to guide screening for aggressive prostate cancer : development and validation in large scale cohorts ', B M J, vol. 360, j5757 . https://doi.org/10.1136/bmj.j5757
Seibert, T M, Fan, C C, Wang, Y, Zuber, V, Karunamuni, R, Parsons, J K, Eeles, R A, Easton, D F, Kote-Jarai, ZS, Al Olama, A A, Garcia, S B, Muir, K, Grönberg, H, Wiklund, F, Aly, M, Schleutker, J, Sipeky, C, Tammela, T L, Nordestgaard, B G, Nielsen, S F, Weischer, M, Bisbjerg, R, Røder, M A, Iversen, P, Key, T J, Travis, R C, Neal, D E, Donovan, J L, Hamdy, F C, Pharoah, P, Pashayan, N, Khaw, K-T, Maier, C, Vogel, W, Luedeke, M, Herkommer, K, Kibel, A S, Cybulski, C, Wokolorczyk, D, Kluzniak, W, Cannon-Albright, L, Brenner, H, Cuk, K, Saum, K-U, Park, J Y, Sellers, T A, Slavov, C, Kaneva, R, Mitev, V, Batra, J & PRACTICAL Consortium 2018, ' Polygenic hazard score to guide screening for aggressive prostate cancer : development and validation in large scale cohorts ', Bmj, vol. 360, pp. j5757 . https://doi.org/10.1136/bmj.j5757
Seibert, T M, Fan, C C, Wang, Y, Zuber, V, Karunamuni, R, Parsons, J K, Eeles, R A, Easton, D F, Kote-Jarai, Z, Al Olama, A A, Garcia, S B, Muir, K, Grönberg, H, Wiklund, F, Aly, M, Schleutker, J, Sipeky, C, Tammela, T L J, Nordestgaard, B G, Nielsen, S F, Weischer, M, Bisbjerg, R, Røder, M A, Iversen, P, Key, T J, Travis, R C, Neal, D E, Donovan, J L, Hamdy, F C, Pharoah, P, Pashayan, N, Khaw, K T, Maier, C, Vogel, W, Luedeke, M, Herkommer, K, Kibel, A S, Cybulski, C, Wokolorczyk, D, Kluzniak, W, Cannon-Albright, L, Brenner, H, Cuk, K, Saum, K U, Park, J Y, Sellers, T A, Slavov, C, Kaneva, R, Mitev, V, Batra, J, Clements, J A, Spurdle, A, Teixeira, M R, Paulo, P, Maia, S, Pandha, H, Michael, A, Kierzek, A, Karow, D S, Mills, I G, Andreassen, O A & Dale, A M 2018, ' Polygenic hazard score to guide screening for aggressive prostate cancer : development and validation in large-scale cohorts ', BMJ, vol. 360, j5757 . https://doi.org/10.1136/bmj.j5757
Translational Cancer Research
Seibert, T M, Fan, C C, Wang, Y, Zuber, V, Karunamuni, R, Parsons, J K, Eeles, R A, Easton, D F, Kote-Jarai, ZS, Al Olama, A A, Garcia, S B, Muir, K, Grönberg, H, Wiklund, F, Aly, M, Schleutker, J, Sipeky, C, Tammela, T L, Nordestgaard, B G, Nielsen, S F, Weischer, M, Bisbjerg, R, Røder, M A, Iversen, P, Key, T J, Travis, R C, Neal, D E, Donovan, J L, Hamdy, F C, Pharoah, P, Pashayan, N, Khaw, K-T, Maier, C, Vogel, W, Luedeke, M, Herkommer, K, Kibel, A S, Cybulski, C, Wokolorczyk, D, Kluzniak, W, Cannon-Albright, L, Brenner, H, Cuk, K, Saum, K-U, Park, J Y, Sellers, T A, Slavov, C, Kaneva, R, Mitev, V, Mills, I G & PRACTICAL Consortium* 2018, ' Polygenic hazard score to guide screening for aggressive prostate cancer development and validation in large scale cohorts ' British Medical Journal, vol. 360, pp. j5757 . DOI: 10.1136/bmj.j5757

Objectives To develop and validate a genetic tool to predict age of onset of aggressive prostate cancer (PCa) and to guide decisions of who to screen and at what age. Design Analysis of genotype, PCa status, and age to select single nucleotide polymo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69cb26206b519e96c3d7c5b045165a1c
http://juuli.fi/Record/0287370718

Fine-needle aspiration of secondary malignancies of the penis: A report of three cases

Autor: Elena Tsanou, Evdoxia Sintou-Mantela, Lina Pappa, Vassiliki Malamou-Mitsi, Evagelos Grammeniatis

Publikováno v: Diagnostic Cytopathology. 29:229-232

Metastatic malignancy to the penis is an uncommon clinicopathologic entity, with only 300 cases reported since 1870. Of the reported cases, 75% were secondary to genitourinary primary tumors. Priapism is the most frequent symptom, although dysuria, u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e87372a89288004bc02d9afcd3cdbe80
https://doi.org/10.1002/dc.10354

Changes in incidence, survival and mortality of prostate cancer in Europe and the United States in the PSA era: additional diagnoses and avoided deaths

Autor: Neppl-Huber, C, Zappa, M, Coebergh, J W, Rapiti Aylward, Elisabetta, Rachtan, J, Holleczek, B, Rosso, S, Aareleid, T, Brenner, H, Gondos, A, EUNICE Survival Working Group

Publikováno v: Annals of Oncology, 23(5), 1325-1334. Elsevier Ltd.
Annals of Oncology, Vol. 23, No 5 (2012) pp. 1325-34

We describe changes in prostate cancer incidence, survival and mortality and the resulting impact in additional diagnoses and avoided deaths in European areas and the United States.Using data from 12 European cancer registries and the Surveillance, E

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2336bf54c0081c70388eb0233d44d359
https://pure.eur.nl/en/publications/4ea49dc8-a453-438e-9ef4-97acaa24a562

Endometrioid Carcinoma of the Prostate. The Diagnostic Value of Leu7 and Prostatic Specific Antigen

Autor: Stavropoulos, N. E., Ioachim, E., Sidoni, K., Stefanou, D. G., Klouvas, G. D., Pavlidis, Nicholas

Publikováno v: British journal of urology

Summary— In a case of endometrioid carcinoma of the prostate the expression of Leu7 and prostatic specific antigen (PSA) was studied immunohistochemically on paraffin sections. The same markers were studied in 14 cases of prostatic cancer and 14 ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::881ed1de84cd44536fd7591905d6c66c
https://gnosis.library.ucy.ac.cy/handle/7/41746