Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Prostate stem cells"'
Autor:
Zuzana Kahounová, Ján Remšík, Radek Fedr, Jan Bouchal, Alena Mičková, Eva Slabáková, Lucia Binó, Aleš Hampl, Karel Souček
Publikováno v:
Stem Cell Research, Vol 46, Iss , Pp 101844- (2020)
Deciphering the properties of adult stem cells is crucial for understanding of their role in healthy tissue and in cancer progression as well. Both stem cells and cancer stem cells have shown association with epithelial-to-mesenchymal transition (EMT
Externí odkaz:
https://doaj.org/article/86a34fde54fb4d0281b36574a5423019
Publikováno v:
Stem Cell Reports, Vol 10, Iss 1, Pp 228-242 (2018)
Summary: The existence of slow-cycling luminal cells in the prostate has been suggested, but their identity and functional properties remain unknown. Using a bigenic mouse model to earmark, isolate, and characterize the quiescent stem-like cells, we
Externí odkaz:
https://doaj.org/article/7a3a1029f7624f009e17ee59ea643df2
Publikováno v:
Stem Cell Research, Vol 16, Iss 3, Pp 597-606 (2016)
CD133 is widely used as a marker for stem/progenitor cells in many organ systems. Previous studies using in vitro stem cell assays have suggested that the CD133-expressing prostate basal cells may serve as the putative prostate stem cells. However, t
Externí odkaz:
https://doaj.org/article/197e902e0ab44457a1e64f1bb0aa227e
Publikováno v:
Stem Cell Research, Vol 16, Iss 3, Pp 682-691 (2016)
Recent lineage tracing studies showed that the prostate basal and luminal cells in adult mice are two independent lineages under the physiological condition, but basal cells are capable of generating luminal progenies during bacterial infection-induc
Externí odkaz:
https://doaj.org/article/ea76fc70a8b9441498d00f7062d2c6f5
Autor:
Paola Grazioli, Antonella Stoppacciaro, Chiara Di Stefano, Margherita Pesce, Antonella D'Amore, Anna Riccioli, Michele Regno, Fabrizio Padula, Rosaria Anna Fontanella, Rita Canipari, Antonio Filippini, Elio Ziparo, Paola De Cesaris, Micol Elena Fiori, Donatella Starace, Antonio Francesco Campese
Publikováno v:
Oncotarget
In human prostate cancer (PCa), the neuroendocrine cells, expressing the prostate cancer stem cell (CSC) marker CD44, may be resistant to androgen ablation and promote tumor recurrence. During the study of heterogeneity of the highly aggressive neuro
Autor:
Yue Lu, Shuai Gong, Dean G. Tang, Amanda Tracz, Dingxiao Zhang, Jianjun Shen, Collene R. Jeter
Publikováno v:
Stem Cell Reports, Vol 10, Iss 1, Pp 228-242 (2018)
Stem Cell Reports
Stem Cell Reports
Summary The existence of slow-cycling luminal cells in the prostate has been suggested, but their identity and functional properties remain unknown. Using a bigenic mouse model to earmark, isolate, and characterize the quiescent stem-like cells, we i
Publikováno v:
Stem Cell Research, Vol 16, Iss 3, Pp 682-691 (2016)
Recent lineage tracing studies showed that the prostate basal and luminal cells in adult mice are two independent lineages under the physiological condition, but basal cells are capable of generating luminal progenies during bacterial infection-induc
Autor:
Corinna Klein, Martin R. Sprick, Thomas Höfner, Christian Eisen, Teresa Rigo-Watermeier, Axel Haferkamp
Publikováno v:
Journal of Cellular and Molecular Medicine
The long-term propagation of basal prostate progenitor cells ex vivo has been very difficult in the past. The development of novel methods to expand prostate progenitor cells in vitro allows determining their cell surface phenotype in greater detail.
Publikováno v:
Oncology Letters
With increases in the mortality rate and number of patients with prostate cancer (PCa), PCa, particularly the advanced and metastatic disease, has been the focus of a number of studies globally. Over the past seven decades, androgen deprivation thera
Autor:
Scott A. Crist, Hsing-Hui Wang, Timothy L. Ratliff, Bin-Da Chan, Cagri A. Savran, Grant N. Burcham, Travis J. Jerde, Liang Wang
Publikováno v:
The Prostate
BACKGROUND The presence of inflammation in prostate cancer (PCa) and benign prostate hyperplasia (BPH) has been well described but the cellular mechanisms by which inflammation modulates the prostate are currently unclear. Prostate stem cells (PSC) n