Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Prostaglandin E receptor 3"'
Publikováno v:
Cornea
PURPOSE: PGF(2α) analogs are commonly used to treat glaucoma and are associated with higher rates of meibomian gland dysfunction (MGD). The purpose of this study was to evaluate the physiological effects of PGF(2α) and PGE(2) on immortalized human
Akademický článek
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Autor:
Lili Guo, Seunghun Paul Lee, George Ho, Lisa Norquay, Ivona Bakaj, Bin Zhu, Matthew Rankin, Jack Kauffman, Mark J. Macielag, Xuqing Zhang
Publikováno v:
ACS Med Chem Lett
[Image: see text] A novel series of pyridones were discovered as potent EP3 antagonists. Optimization guided by EP3 binding and functional assays as well as by eADME and PK profiling led to multiple compounds with good physical properties, excellent
Publikováno v:
Plant Biotechnology Journal
Summary ERECTA PANICLE 3 (EP3) and ORYZA SATIVA F‐BOX KELCH 1 (OsFBK1) proteins share 57% and 54% sequence identity with the Arabidopsis F‐box protein HAWAIIAN SKIRT (HWS). Previously we showed that EP3 is a functional orthologue of HWS. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a10ec2db3df5765585ee864774bdc15f
Autor:
Gunawan Suryoputro, Herri Mulyono
Publikováno v:
Science for Education Today. 10:105-123
Introduction. This current survey attempts to explore university teachers and students’ perception of using social media to promote an authentic learning environment. Materials and Methods. To this end, 249 university teachers and 329 students part
Autor:
Gang Yu, Jing Leng, Jinwei Guo, Ruhui Zeng, Bin Liu, Yingbi Zhou, Yingzhan Zhang, Yineng Xu, Jiahui Ge, Tingting Guo, Xiangzhong Wu, Yehu Yin
Publikováno v:
The FASEB Journal. 34:2568-2578
Although recognized to have an in vivo vasodepressor effect blunted by the vasoconstrictor effect of E-prostanoid receptor-3 (EP3), prostaglandin E2 (PGE2 ) evokes contractions of many vascular beds that are sensitive to antagonizing the thromboxane
Publikováno v:
Journal of Scientific Computing. 89
Autor:
Kjetil Taskén, Albert J. R. Heck, Piero Giansanti, Anna Mari Lone, Aurelien Dugourd, Enio Gjerga, Julio Saez-Rodriguez, Marthe Jøntvedt Jørgensen, Arjen Scholten
Publikováno v:
Science Signaling
Science Signaling, 14(703), 1. American Association for the Advancement of Science
Science Signaling, 14(703), 1. American Association for the Advancement of Science
Prostaglandin E2 (PGE2) promotes an immunosuppressive microenvironment in cancer, partly by signaling through four receptors (EP1, EP2, EP3, and EP4) on T cells. Here, we comprehensively characterized PGE2 signaling networks in helper, cytotoxic, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::241d3d22a45fbac87ab5d9565018a9c1
https://dspace.library.uu.nl/handle/1874/413152
https://dspace.library.uu.nl/handle/1874/413152
Publikováno v:
Neuro Oncol
OBJECTIVES Tumor Treating Fields (TTFields) are approved in combination with temozolomide for newly diagnosed glioblastoma (GBM). TTFields are low-intensity alternating electric fields that are thought to disturb mitotic macromolecules’ assembly. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a901d4b86613e1ca516f683ef11b85d
https://europepmc.org/articles/PMC7650312/
https://europepmc.org/articles/PMC7650312/
Autor:
Pamela Harding, Timothy D. Bryson
Publikováno v:
Biochemical Pharmacology. 195:114858
This review article provides an update for the role of prostaglandin E2 receptors (EP1, EP2, EP3 and EP4) in cardiovascular disease. Where possible we have reported citations from the last decade although this was not possible for all of the topics c