Synthesis and biochemical characterization of naphthoquinone derivatives targeting bacterial histidine kinases.

Autor: Ishikawa T; Graduate School of Education, Okayama University, Okayama, Japan. teruhiko@cc.okayama-u.ac.jp., Eguchi Y; Department of Science and Technology on Food Safety, Faculty of Biology-Oriented Science and Technology, Kindai University, Wakayama, Japan., Igarashi M; Institute of Microbial Chemistry (BIKAKEN), Tokyo, Japan., Okajima T; SANKEN (The Institute of Scientific and Industrial Research), Osaka University, Osaka, Japan., Mita K; Graduate School of Education, Okayama University, Okayama, Japan., Yamasaki Y; Graduate School of Education, Okayama University, Okayama, Japan., Sumikura K; Graduate School of Education, Okayama University, Okayama, Japan., Okumura T; Graduate School of Education, Okayama University, Okayama, Japan., Tabuchi Y; Graduate School of Education, Okayama University, Okayama, Japan., Hayashi C; Institute of Microbial Chemistry (BIKAKEN), Tokyo, Japan., Pasqua M; Istituto Pasteur Italy, Department of Biology and Biotechnology, 'C. Darwin', Sapienza University of Rome, Rome, Italy., Coluccia M; Istituto Pasteur Italy, Department of Biology and Biotechnology, 'C. Darwin', Sapienza University of Rome, Rome, Italy., Prosseda G; Istituto Pasteur Italy, Department of Biology and Biotechnology, 'C. Darwin', Sapienza University of Rome, Rome, Italy., Colonna B; Istituto Pasteur Italy, Department of Biology and Biotechnology, 'C. Darwin', Sapienza University of Rome, Rome, Italy., Kohayakawa C; Department of Lead Exploration Units, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan., Tani A; Compound Library Screening Center, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan., Haruta JI; Department of Lead Exploration Units, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan., Utsumi R; SANKEN (The Institute of Scientific and Industrial Research), Osaka University, Osaka, Japan. utsumi@sanken.osaka-u.ac.jp.

Publikováno v: The Journal of antibiotics [J Antibiot (Tokyo)] 2024 Aug; Vol. 77 (8), pp. 522-532. Date of Electronic Publication: 2024 Jun 25.

AcrAB efflux pump impacts on the survival of adherent-invasive Escherichia coli strain LF82 inside macrophages

Autor: Fanelli, G., Pasqua, M., Prosseda, G., Grossi, M., Colonna, B.

Publikováno v: Scientific Reports. 13

The tripartite complex AcrAB-TolC is the major RND pump in Escherichia coli and other Enterobacteriaceae. It consists of the AcrB transporter, which is embedded in the inner membrane, the AcrA adapter located in the periplasm, and the channel protein

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e753031abcd7809c667cfae95b2c6026
https://doi.org/10.1038/s41598-023-29817-0

Diffusible signal factors (DSFs) bind and repress VirF, the leading virulence activator of Shigella flexneri.

Autor: Trirocco R; Institute Pasteur Italia, Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, p.le Aldo Moro 5, 00185, Rome, Italy., Pasqua M; Institute Pasteur Italia, Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, p.le Aldo Moro 5, 00185, Rome, Italy., Tramonti A; Institute of Molecular Biology and Pathology, National Research Council, Rome, Italy., Colonna B; Institute Pasteur Italia, Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, p.le Aldo Moro 5, 00185, Rome, Italy., Paiardini A; Department of Biochemical Sciences, Sapienza University of Rome, p.le Aldo Moro 5, 00185, Rome, Italy., Prosseda G; Institute Pasteur Italia, Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, p.le Aldo Moro 5, 00185, Rome, Italy. gianni.prosseda@uniroma1.it.

Publikováno v: Scientific reports [Sci Rep] 2023 Aug 14; Vol. 13 (1), pp. 13170. Date of Electronic Publication: 2023 Aug 14.

Role of the MDR Efflux Pump AcrAB in Epithelial Cell Invasion by Shigella flexneri .

Autor: Coluccia M; Istituto Pasteur Italy, Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, 00185 Rome, Italy., Béranger A; Istituto Pasteur Italy, Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, 00185 Rome, Italy., Trirocco R; Istituto Pasteur Italy, Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, 00185 Rome, Italy., Fanelli G; Istituto Pasteur Italy, Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, 00185 Rome, Italy., Zanzi F; Istituto Pasteur Italy, Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, 00185 Rome, Italy., Colonna B; Istituto Pasteur Italy, Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, 00185 Rome, Italy., Grossi M; Istituto Pasteur Italy, Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, 00185 Rome, Italy., Prosseda G; Istituto Pasteur Italy, Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, 00185 Rome, Italy., Pasqua M; Istituto Pasteur Italy, Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, 00185 Rome, Italy.

Publikováno v: Biomolecules [Biomolecules] 2023 May 11; Vol. 13 (5). Date of Electronic Publication: 2023 May 11.

Characterization of an emergent clone of enteroinvasive Escherichia coli circulating in Europe

Autor: Michelacci, V., Prosseda, G., Maugliani, A., Tozzoli, R., Sanchez, S., Herrera-León, S., Dallman, T., Jenkins, C., Caprioli, A., Morabito, S.

Publikováno v: In Clinical Microbiology and Infection March 2016 22(3):287-287