Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Prosper Tshilobo Lukusa"'
Autor:
Tite Minga Mikobi, Nelly Ciombo Kamuanya, Emmanuelle Ketsia Bokashanga Mikobi, Thérèse Ilunga Kalela, Pierre Zalagile Akilimali, Prosper Tshilobo Lukusa
Publikováno v:
eJHaem, Vol 4, Iss 4, Pp 977-983 (2023)
Abstract Pregnancy is accompanied by hormonal changes. These relate mainly to progesterone and placenate growth factor. Hemodynamic changes are also observed. in a sickle cell pregnant woman, all these changes have a direct effect on hypoxia. This is
Externí odkaz:
https://doaj.org/article/816ec4bac0f6410dab214ec3d08eddb6
Autor:
Gloire Mbayabo, Mamy Ngole, Paul Kabuyi Lumbala, Aimé Lumaka, Valerie Race, Gert Matthijs, Tite Minga Mikobi, Koenraad Devriendt, Chris Van Geet, Prosper Tshilobo Lukusa
Publikováno v:
Hematology, Vol 28, Iss 1 (2023)
ABSTRACTBackground: Sickle Cell Anemia (SCA) is the most common genetic disease worldwide caused by a single mutation in the gene HBB. The disease severity is very variable and depends on many factors. We evaluated the clinical and biological profile
Externí odkaz:
https://doaj.org/article/34f2e67d7afd4d9691ea584959c2579a
Autor:
Paul Kabuyi Lumbala, Gloire Mbayabo, Mamy Nzita Ngole, Aimé Lumaka, Valerie Race, Gert Matthijs, Chris Van Geet, Prosper Tshilobo Lukusa, Koenraad Devriendt, Tite Minga Mikobi
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0278478 (2022)
BackgroundSickle cell anemia (SCA) is a monogenic hemoglobinopathy associated with severe acute and chronic complications, with the highest incidence worldwide in Sub-Saharan Africa. The wide variability in clinical manifestations suggest that a unif
Externí odkaz:
https://doaj.org/article/fe73b06b50184c348dbc70de6f338622
Publikováno v:
PLoS ONE, Vol 17, Iss 10 (2022)
Introduction Malaria is associated with high morbidity during pregnancy. Homozygous sickle cell pregnant women are even more exposed during complicated malaria. The objective of the study was to evaluate the maternal and fetal morbidity of homozygous
Externí odkaz:
https://doaj.org/article/40e1bb4ec5c6479785872f5866881ccf
Publikováno v:
Mediterranean Journal of Hematology and Infectious Diseases, Vol 11, Iss 1 (2019)
FHb and alpha-thal are two genetic factors that modulate the clinical expression of sickle cell disease. Objective: to determine the beneficial role of FHb and alpha-thal on fetal and maternal morbidity during pregnancy in sickle cell patients.
Externí odkaz:
https://doaj.org/article/f207b6da62ea45c6a12f75a1432c1140
Autor:
Gerrye Mubungu, Mathieu Roelants, Aimé Lumaka, Prince Makay, Dahlie Tshika, Toni Lubala, Prosper Tshilobo Lukusa, Koenraad Devriendt
Publikováno v:
American Journal of Medical Genetics Part A. 188:3063-3070
The evaluation of dysmorphism is often subjective because many continuous traits are not easily measured or lack normal values. Because many common morphologic profiles vary between populations, population-specific reference ranges of relevant traits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40711b6c079f666a57696c0e287c67d0
https://doi.org/10.1002/ajmg.a.62958
https://doi.org/10.1002/ajmg.a.62958
Autor:
Gloire Mbayabo, Paul Kabuyi Lumbala, Mamy Ngole, Aimé Lumaka, Valérie Race, Gert Matthijs, Tite Minga Mikobi, Koenraad Devriendt, Chris Van Geet, Prosper Tshilobo Lukusa
Sickle cell anemia is highly prevalent in Central Africa. The disease causes severe manifestations in children requiring treatment. Hydroxyurea is currently the most effective drug treatment. Therefore, we evaluated the use of HU in children living i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc40a17b059634fbc0559c09f29e822e
https://doi.org/10.22541/au.168321426.61233927/v1
https://doi.org/10.22541/au.168321426.61233927/v1
Autor:
Mamy Ngole, Valerie Race, Gloire Mbayabo, Paul Lumbala, Cathy Songo, Prosper Tshilobo Lukusa, Koenraad Devriendt, Gert Matthijs, Aimé Lumaka
BACKGROUND: Hemoglobin-based tests form the reference diagnostic test for SCA. In limited resource countries, these tests face limitations including cost, low sensitivity due to recurrent transfusions in endemic malaria region, and interference from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ba0a5d4dd2f0b1690af19fc0c3a01cd
https://lirias.kuleuven.be/handle/20.500.12942/694836
https://lirias.kuleuven.be/handle/20.500.12942/694836
Autor:
Laetitia Mpola Mavinga, Veronique Kakiese, Mamy Ngole, Cathy Songo, Aimé Lumaka, Valerie Race, Prosper Tshilobo Lukusa, Koenraad Devriendt
Publikováno v:
European Journal of Medical Genetics. 65:104611
Oculocutaneous albinism (OCA) is an autosomal recessive genetic disorder associated with reduced or absent pigmentation in the skin, hair and eyes. OCA type 2 (OCA2) is the most common type in Sub-Saharan Africa, related to a recurrent 2.7 kb intrage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9da921fafee5fa8d3e3d3bd20ce405e
https://doi.org/10.1016/j.ejmg.2022.104611
https://doi.org/10.1016/j.ejmg.2022.104611
Autor:
Tite Minga, Mikobi, Prosper Tshilobo, Lukusa, Michel Ntetani, Aloni, Aimé, Lumaka, Pierre Zalagile, Akilimali, Koenraad, Devriendt, Gert, Matthijs, Jean-Marie, Mbuyi Muamba, Valerie, Race
Publikováno v:
Journal of clinical laboratory analysis. 32(1)
BACKGROUND: Information about the association with alpha thalassemia in sickle cell patients is unknown in the Democratic Republic of Congo. There is very little data on the alpha thalassemia in patients suffering from sickle cell anemia in Central A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1db9ad8d708cb274758b51a5572bf2a8
https://pubmed.ncbi.nlm.nih.gov/28276593
https://pubmed.ncbi.nlm.nih.gov/28276593