Specific determinants of conantokins that dictate their selectivity for the NR2B subunit of N-methyl-d-aspartate receptors

Autor: Sheng, Z., Prorok, M., Castellino, F.J.

Publikováno v: In Neuroscience 27 October 2010 170(3):703-710

Filarial nematode phenotypic screening cascade to identify compounds with anti-parasitic activity for drug discovery optimization.

Autor: Hawryluk N; Bristol Myers Squibb, San Diego, CA, USA. Electronic address: nataliehawryluk@gmail.com., Zhiru L; New England Biolabs, Ipswich, MA, USA., Carlow C; New England Biolabs, Ipswich, MA, USA., Gokool S; Northwick Park Institute for Medical Research, London, UK., Townson S; Northwick Park Institute for Medical Research, London, UK., Kreiss T; Sokol Institute of Pharmaceutical Life Sciences, Montclair State University, Montclair, NJ, USA., Chojnowski A; Sokol Institute of Pharmaceutical Life Sciences, Montclair State University, Montclair, NJ, USA., Prorok M; Sokol Institute of Pharmaceutical Life Sciences, Montclair State University, Montclair, NJ, USA., Siekierka J; Sokol Institute of Pharmaceutical Life Sciences, Montclair State University, Montclair, NJ, USA., Ehrens A; Institute for Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Germany; German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, Bonn, Germany., Koschel M; Institute for Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Germany., Lhermitte-Vallarino N; German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, Bonn, Germany., Martin C; Unité Molécules de Communication et Adaptation des Microorganismes (MCAM, UMR 7245), Muséum national d'Histoire naturelle, Paris, France., Hoerauf A; Institute for Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Germany; German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, Bonn, Germany., Hernandez G; Bristol Myers Squibb, San Diego, CA, USA., Canan S; Bristol Myers Squibb, San Diego, CA, USA., Khetani V; Bristol Myers Squibb, Summit, NJ, USA., Zeldis J; Celgene Global Health, Summit, NJ, USA., Specht S; Institute for Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Germany; Drugs for Neglected Diseases Initiative, Geneva, Switzerland., Hübner MP; Institute for Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Germany; German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, Bonn, Germany., Scandale I; Drugs for Neglected Diseases Initiative, Geneva, Switzerland.

Publikováno v: International journal for parasitology. Drugs and drug resistance [Int J Parasitol Drugs Drug Resist] 2022 Aug; Vol. 19, pp. 89-97. Date of Electronic Publication: 2022 Jun 23.

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A Conantokin Peptide Con-T[M8Q] Inhibits Morphine Dependence with High Potency and Low Side Effects.

Autor: Liu Z; Beijing Institute of Biotechnology, Beijing 100071, China., Yu Z; Beijing Institute of Biotechnology, Beijing 100071, China., Yu S; Beijing Institute of Biotechnology, Beijing 100071, China., Zhu C; Beijing Institute of Biotechnology, Beijing 100071, China., Dong M; Beijing Institute of Biotechnology, Beijing 100071, China., Mao W; Beijing Institute of Biotechnology, Beijing 100071, China., Hu J; Beijing Institute of Biotechnology, Beijing 100071, China., Prorok M; Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA., Su R; Beijing Institute of Toxicology and Pharmacology, Beijing 100850, China., Dai Q; Beijing Institute of Biotechnology, Beijing 100071, China.

Publikováno v: Marine drugs [Mar Drugs] 2021 Jan 19; Vol. 19 (1). Date of Electronic Publication: 2021 Jan 19.