Greenhouse Gas Emissions and Costs of Inhaler Devices in the US.

Autor: Tirumalasetty J; Division of Pulmonary, Allergy, and Critical Care Medicine, Stanford University School of Medicine, Stanford, California., Miller SA; School for Environment and Sustainability, University of Michigan, Ann Arbor., Prescott HC; VA Center for Clinical Management Research, Ann Arbor, Michigan., DeTata S; Division of Pulmonary, Allergy, and Critical Care Medicine, Stanford University School of Medicine, Stanford, California., Arroyo AC; Division of Pulmonary, Allergy, and Critical Care Medicine, Stanford University School of Medicine, Stanford, California., Wilkinson AJK; Respiratory Department, East and North Hertfordshire NHS Trust, Stevenage, United Kingdom., Rabin AS; Pulmonary Section, VA Ann Arbor Healthcare System, Ann Arbor, Michigan.

Publikováno v: JAMA [JAMA] 2024 Sep 24; Vol. 332 (12), pp. 1017-1019.

Evaluating the pharmacokinetics of beclometasone dipropionate/formoterol fumarate/glycopyrronium bromide delivered via pressurised metered-dose inhaler using a low global warming potential propellant.

Autor: Rony F; Global Clinical Development, Chiesi SAS, Bois Colombes, France. Electronic address: f.rony@chiesi.com., Cortellini M; Global Clinical Development, Chiesi Farmaceutici SpA, Parma, Italy., Guasconi A; Global Clinical Development, Chiesi Farmaceutici SpA, Parma, Italy., Mathews KS; Global Clinical Development, Chiesi Farmaceutici SpA, Parma, Italy., Piccinno A; Global Clinical Development, Chiesi Farmaceutici SpA, Parma, Italy., Poli G; Global Clinical Development, Chiesi Farmaceutici SpA, Parma, Italy., Vanhoutte F; Clinical Pharmacology Unit, SGS Belgium NV, Edegem, Belgium., Klein J; Clinical Pharmacology Unit, SGS Belgium NV, Edegem, Belgium.

Publikováno v: Pulmonary pharmacology & therapeutics [Pulm Pharmacol Ther] 2024 Jun; Vol. 85, pp. 102299. Date of Electronic Publication: 2024 Apr 23.

Acute, repeated inhalation toxicity, respiratory system irritation, and mutagenicity studies of 1,1,2,2-tetrafluoroethane (HFC-134) as the impurity in the pharmaceutical propellant 1,1,1,2-tetrafluoroethane (HFA-134a).

Autor: Zhao Y; NMPA Key Laboratory for Quality Research and Evaluation of Pharmaceutical Excipients, Beijing, China.; National Institutes for Food and Drug Control, Beijing, China., Sun H; NMPA Key Laboratory for Quality Research and Evaluation of Pharmaceutical Excipients, Beijing, China.; National Institutes for Food and Drug Control, Beijing, China., Lin F; NMPA Key Laboratory for Quality Research and Evaluation of Pharmaceutical Excipients, Beijing, China.; National Institutes for Food and Drug Control, Beijing, China., Yang H; NMPA Key Laboratory for Quality Research and Evaluation of Pharmaceutical Excipients, Beijing, China.; National Institutes for Food and Drug Control, Beijing, China.

Publikováno v: Drug and chemical toxicology [Drug Chem Toxicol] 2023 Nov; Vol. 46 (5), pp. 841-850. Date of Electronic Publication: 2022 Aug 03.

Metered dose inhalers in the transition to low GWP propellants: what we know and what is missing to make it happen.

Autor: Buttini F; Food and Drug Department, University of Parma, Parma, Italy.; Interdepartmental Center for Innovation in Health Products, Biopharmanet_TEC, University of Parma, Parma, Italy., Glieca S; Food and Drug Department, University of Parma, Parma, Italy., Sonvico F; Food and Drug Department, University of Parma, Parma, Italy.; Interdepartmental Center for Innovation in Health Products, Biopharmanet_TEC, University of Parma, Parma, Italy., Lewis DA; Oz-UK Limited Unit15a, Chippenham, Wiltshire, UK.

Publikováno v: Expert opinion on drug delivery [Expert Opin Drug Deliv] 2023 Jul-Dec; Vol. 20 (8), pp. 1131-1143. Date of Electronic Publication: 2023 Oct 16.

HS-GC-FID method for quantification of HFA-152a in cell culture media, and plasma from a range of species and regulatory compliant validations.

Autor: Kuehl PJ; Lovelace Biomedical, 2425 Ridgecrest Dr. SE, Albuquerque, NM 87108, United States of America. Electronic address: pkuehl@lovelacebiomedical.org., Corr S; Koura, Thornton Science Park, Cheshire, UK., Farrar J; Lovelace Biomedical, 2425 Ridgecrest Dr. SE, Albuquerque, NM 87108, United States of America., McDonald JD; Lovelace Biomedical, 2425 Ridgecrest Dr. SE, Albuquerque, NM 87108, United States of America., Wermer T; Lovelace Biomedical, 2425 Ridgecrest Dr. SE, Albuquerque, NM 87108, United States of America., Weber D; Lovelace Biomedical, 2425 Ridgecrest Dr. SE, Albuquerque, NM 87108, United States of America., Leach C; Lovelace Biomedical, 2425 Ridgecrest Dr. SE, Albuquerque, NM 87108, United States of America.

Publikováno v: Journal of pharmacological and toxicological methods [J Pharmacol Toxicol Methods] 2023 Jul-Aug; Vol. 122, pp. 107271. Date of Electronic Publication: 2023 May 15.