Výsledky vyhledávání - "Proost, J.H."

Akademický článek

Model to describe the degree of twitch potentiation during neuromuscular monitoring

Autor: Eleveld, D.J., Kopman, A.F., Proost, J.H., Wierda, J.M.K.H.

Publikováno v: In British Journal of Anaesthesia March 2004 92(3):373-380

Corrigendum to ’Development of a mechanistic biokinetic model for hepatic bile acid handling to predict possible cholestatic effects of drugs’ [European Journal of Pharmaceutical Sciences 115 (2018) 175-184] (S0928098718300071) (10.1016/j.ejps.2018.01.007))

Autor: Notenboom, S., Weigand, K.M., Proost, J.H., Lipzig, M.M. van, Steeg, E. van de, Broek, P.H.H. van den, Greupink, R., Russel, F.G.M., Groothuis, G.M.M.

Publikováno v: European Journal of Pharmaceutical Sciences, 117, 392-393

The authors regret the molar unit is incorrectly displayed on the x-axis in Fig. 4A and 4C and on the y-axis in Fig. 4B, 4D and Fig. 5. The correct versions of the figures are displayed below together with the unchanged legends. The authors would lik

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7532b5f06399f4bb09a78e2a53bcd2e9
http://resolver.tudelft.nl/uuid:264e051e-a4ad-47b0-9df8-e864497def17

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Development of a mechanistic biokinetic model for hepatic bile acid handling to predict possible cholestatic effects of drugs

Autor: Notenboom, S., Weigand, K.M., Proost, J.H., Lipzig, M.M.H. van, Steeg, E. van de, Broek, P.H.H. van den, Greupink, R., Russel, F.G.M., Groothuis, G.M.M.

Publikováno v: European Journal of Pharmaceutical Sciences, 115, 175-184

Drug-induced liver injury (DILI) is a common reason for drug withdrawal from the market. An important cause of DILI is drug-induced cholestasis. One of the major players involved in drug-induced cholestasis is the bile salt efflux pump (BSEP; ABCB11)

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http://resolver.tudelft.nl/uuid:0039097c-78d6-40a4-b901-df30d53d188f

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Predicting Drug Concentration-Time Profiles in Multiple CNS Compartments Using a Comprehensive Physiologically-Based Pharmacokinetic Model

Autor: Yamamoto, Y., Valitalo, P.A.J., Huntjens, D.R., Proost, J.H., Vermeulen, A., Krauwinkel, W., Beukers, M.W., Berg, D.J. van den, Hartman, R.J., Wong, Y.C., Danhof, M., Hasselt, J.G.C. van, Lange, E.C.M. de

Publikováno v: CPT: Pharmacometrics & Systems Pharmacology, 6(11), 765–777

Drug development targeting the central nervous system (CNS) is challenging due to poor predictability of drug concentrations in various CNS compartments. We developed a generic physiologically based pharmacokinetic (PBPK) model for prediction of drug

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::10a828f8ed78f3ffab87d95756e51463
https://hdl.handle.net/1887/59075

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Akademický článek

Urinary, biliary and faecal excretion of rocuronium in humans

Autor: Proost, J.H., Eriksson, L.I., Mirakhur, R.K., Roest, G., Wierda, J.M.K.H.

Publikováno v: In British Journal of Anaesthesia November 2000 85(5):717-723

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Drug interaction models are better predictors of tolerance/ response to noxious stimuli compared to individual measured parameters

Autor: Hannivoort, L.N., Proost, J.H., Eleveld, D.J., Struys, M.M.R.F., Luginbühl, M., Vereecke, H.E.M.

Publikováno v: European Journal of Anaesthesiology, 30(Supplement 51), 1-2. LIPPINCOTT WILLIAMS & WILKINS

Background and Goal of Study: This study continues the pursuit of the parameter with the best correlation to the probability of response to noxious stimuli of different intensity. We used data from a previous study by Heyse et al.1 on the interaction

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::a5a56839c93f820b6752642f4dcb2457
https://research.rug.nl/en/publications/6cbd43e4-bedc-4c31-ad38-f5ef8905e33f

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Population pharmacokinetics of cutamesine in rats using NONMEM, 11C-SA4503, and microPET

Autor: Ramakrishnan, N.K., Pilla Reddy, V., Proost, J.H., Nyakas, C.J., Kwizera, C., Sijbesma, J.W.A., Elsinga, P.H., Ishiwata, K., Dierckx, R.A.J.O., Van Waarde, A.

Publikováno v: European Journal of Nuclear Medicine and Molecular Imaging, 39, S301-S302. SPRINGER

Cutamesine (SA4503) is a selective sigma-1 receptor agonist, currently in Phase II clinical trials for depression and post stroke neurological disturbances. Cutamesine has been found to be effective in several rodent models of amnesia and depression.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::2ea763650be2aece122adab99dbdcc54
https://research.rug.nl/en/publications/0a853c75-640e-42a7-9259-ea33f9555f6e

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