Diet-Dependent Changes of the DNA Methylome Using a Göttingen Minipig Model for Obesity

Autor: Y. Feng, S. Cirera, E. Taşöz, Y. Liu, L. H. Olsen, B. Ø. Christoffersen, H. D. Pedersen, T. P. Ludvigsen, R. K. Kirk, C. Schumacher-Petersen, Y. Deng, M. Fredholm, F. Gao

Publikováno v: Frontiers in Genetics, Vol 12 (2021)

Objective: Environmental factors can influence obesity by epigenetic mechanisms. The aim of this study was to investigate obesity-related epigenetic changes and the potential for reversal of these changes in the liver of Göttingen minipigs subjected

Externí odkaz: https://doaj.org/article/d009de7d1266488ba4a453685cf10c82

Promoter Methylation of Cancer Stem Cell Surface Markers as an Epigenetic Biomarker for Prognosis of Oral Squamous Cell Carcinoma

Autor: Yu Kyeong Han, Ha Young Park, Sae-Gwang Park, Jae Joon Hwang, Hae Ryoun Park, Joo Mi Yi

Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 23; Pages: 14624

Growing evidence suggests that genetic and epigenetic factors, including environmental factors, contribute to the development of oral squamous cell carcinoma (OSCC). Here, we investigated the transcriptional silencing of the CD24, CD44, CD133, and CD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e18d0ca97af1106c3ed5be5448c6fc1

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Zvýšená produkce mRNA dioxygenázy TET1, nízká hladina metylace DNA and změny exprese lidského endogenního retroviru ERVWE1 v nádorech zárodečných buněk

Autor: Benešová, Martina

TGCTs are tumors of male germ cells. They comprise of seminomas and non-seminomas (embryonal carcinoma, yolk sac tumor, choriocarcinoma, and teratoma). GCT types differ in the stage of differentiation, from undifferentiated seminoma to more different

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2186::1f95ff50a076dbd75b4a4ab5aac6a5ac
http://www.nusl.cz/ntk/nusl-410936

Looking Beyond the 5-HTTLPR Polymorphism: Genetic and Epigenetic Layers of Regulation Affecting the Serotonin Transporter Gene Expression

Autor: Monica Rinaldi, Davide Seripa, Sandra Iurescia

Publikováno v: Molecular neurobiology (Online) (2017). doi:10.1007/s12035-016-0304-6
info:cnr-pdr/source/autori:Iurescia S., Seripa D., Rinaldi M./titolo:Looking Beyond the 5-HTTLPR Polymorphism: Genetic and Epigenetic Layers of Regulation Affecting the Serotonin Transporter Gene Expression/doi:10.1007%2Fs12035-016-0304-6/rivista:Molecular neurobiology (Online)/anno:2017/pagina_da:/pagina_a:/intervallo_pagine:/volume

Serotonin (5-HT) is a neurotransmitter that regulates fundamental aspects of brain development, physiology and behaviour. The serotonin transporter (5-HTT) is deputized to the reuptake of 5-HT from the intersynaptic space in the presynaptic neurons.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e974601b83a4f71cfa1a5873fcbc20da
https://doi.org/10.1007/s12035-016-0304-6