Zobrazeno 1 - 10
of 896
pro vyhledávání: '"Prokineticin"'
Autor:
Roberta Lattanzi, Ida Casella, Maria Rosaria Fullone, Daniela Maftei, Martina Vincenzi, Rossella Miele
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 2, Pp 1607-1620 (2024)
Melanocortin receptor accessory protein 2 (MRAP2) is a membrane protein that binds multiple G protein-coupled receptors (GPCRs) involved in the control of energy homeostasis, including prokineticin receptors. These GPCRs are expressed both centrally
Externí odkaz:
https://doaj.org/article/d96dec543800442f8c80ab026793f435
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-13 (2023)
Abstract Background Our preliminary study indicates that the multi-functional protein, prokineticin 2 (Prok2), is upregulated in osteoarthritic (OA) chondrocytes as a target of the hypoxia-inducible factor (HIF)-2α. This study aims to elucidate the
Externí odkaz:
https://doaj.org/article/53288813e39e423c92d6ad8903c7accb
Autor:
Roberta Lattanzi, Rossella Miele
Publikováno v:
Life, Vol 14, Iss 10, p 1254 (2024)
Prokineticins (PKs) are low molecular weight proteins that exert their effects by binding to two seven-transmembrane G-protein-coupled receptors (prokineticin receptors, PKRs). The prokineticin system is an important player in the development of vari
Externí odkaz:
https://doaj.org/article/2dfc5a39f847451388e94afd3d8344ad
Autor:
Roberta Lattanzi, Rossella Miele
Publikováno v:
Encyclopedia, Vol 3, Iss 4, Pp 1498-1508 (2023)
G protein-coupled receptors (GPCRs) are transmembrane proteins that mediate the intracellular pathway of signals not only through heterotrimeric GTP-binding proteins (G proteins) but also through their associations with a variety of additional partne
Externí odkaz:
https://doaj.org/article/fba1b6c03cde48b1aded1961f4d595b2
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 14, p 7816 (2024)
The prokineticin system plays a role in hypothalamic neurons in the control of energy homeostasis. Prokineticin receptors (PKR1 and PKR2), like other G-protein-coupled receptors (GPCRs) are involved in the regulation of energy intake and expenditure
Externí odkaz:
https://doaj.org/article/ddfede3348ad44e99b1db087d29ce796
Akademický článek
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Autor:
Roberta Lattanzi, Rossella Miele
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 12, Pp 6323-6332 (2022)
The prokineticin family comprises a group of secreted peptides that can be classified as chemokines based on their structural features and chemotactic and immunomodulatory functions. Prokineticins (PKs) bind with high affinity to two G protein-couple
Externí odkaz:
https://doaj.org/article/32a3b0270e90458a80eb65df453d2b6c
Autor:
Qianqian Tu, Xiaoyan Yu, Wei Xie, Yetao Luo, Hong Tang, Kai Chen, Yanting Ruan, Yue Li, Jie Zhou, Yibing Yin, Dapeng Chen, Zhixin Song
Publikováno v:
International Journal of Infectious Diseases, Vol 125, Iss , Pp 103-113 (2022)
ABSTRACT: Objectives: Bacterial pneumonia is a common serious infectious disease with high morbidity and mortality. Prokineticin 2 (PK2) has recently been identified as a novel immunomodulator in a variety of diseases; however, its role in bacterial
Externí odkaz:
https://doaj.org/article/bf88f6eaaef440328efdd98757159f79
Autor:
Hadi Younes, Ioanna Kyritsi, Zineb Mahrougui, Mohamed Benharouga, Nadia Alfaidy, Christel Marquette
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15428 (2023)
Prokineticins are a family of small proteins with diverse roles in various tissues, including the brain. However, their specific effects on different cerebral cell types and blood–brain barrier (BBB) function remain unclear. The aim of this study w
Externí odkaz:
https://doaj.org/article/7d51ea66d450463fb8294c5250bd8043
Autor:
Zhao Jiang, Tianxiao Zhang, Wei Han, Jing Xiao, Wenpei Zhang, Xiaochen Wang, Jianing Liu, Ying Yang, Congying Yang, Fanglin Guan, Tao Li, John P. Rice
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Methamphetamine use disorder (MUD) has become a global problem due to the highly addictive nature of methamphetamine. Earlier research have demonstrated that PROK2 functions as a compensatory and protective response against neurotoxic str
Externí odkaz:
https://doaj.org/article/f319a7ec5b6b48aea17156d7c8edfc08