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of 7
pro vyhledávání: '"Progya P. Mukherjee"'
Autor:
Progya P. Mukherjee, Karim P.M. Labib
Publikováno v:
Cell Reports, Vol 28, Iss 11, Pp 2777-2783.e4 (2019)
Summary: Disassembly of the replisome is the final step of chromosome duplication in eukaryotes. In budding yeast and metazoa, cullin ubiquitin ligases are required to ubiquitylate the Cdc45-MCM-GINS (CMG) helicase that lies at the heart of the repli
Externí odkaz:
https://doaj.org/article/79fe2125934f41b0843149ea5db864c7
Publikováno v:
eLife, Vol 9 (2020)
The eukaryotic replisome assembles around the CMG helicase, which stably associates with DNA replication forks throughout elongation. When replication terminates, CMG is ubiquitylated on its Mcm7 subunit and disassembled by the Cdc48/p97 ATPase. Unti
Externí odkaz:
https://doaj.org/article/6c8161f617dc48f6bb5652e3e06dc23f
Autor:
Cecile Evrin, Albert Serra‐Cardona, Shoufu Duan, Progya P Mukherjee, Zhiguo Zhang, Karim P M Labib
Publikováno v:
The EMBO Journal. 41
Nucleosomes are disrupted transiently during eukaryotic transcription, yet the displaced histones must be retained and redeposited onto DNA, to preserve nucleosome density and associated histone modifications. Here, we show that the essential Spt5 pr
Publikováno v:
Organic & Biomolecular Chemistry. 14:5832-5842
The development of robust tools and practical RNA labeling strategies that would facilitate the biophysical analysis of RNA in both cell-free and cellular systems will have profound implications in the discovery of new RNA diagnostic tools and therap
Autor:
Seergazhi G. Srivatsan, Progya P. Mukherjee, Sanjeev Galande, Soumitra Athavale, Ashwin Kelkar, Anupam A. Sawant, Arun A. Tanpure
Publikováno v:
Nucleic Acids Research
Cellular RNA labeling strategies based on bioorthogonal chemical reactions are much less developed in comparison to glycan, protein and DNA due to its inherent instability and lack of effective methods to introduce bioorthogonal reactive functionalit
Autor:
Maric M; MRC Protein Phosphorylation and Ubiquitylation Unit, Sir James Black Centre, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK., Mukherjee P; MRC Protein Phosphorylation and Ubiquitylation Unit, Sir James Black Centre, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK., Tatham MH; Gene Regulation and Expression Division, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK., Hay R; Gene Regulation and Expression Division, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK., Labib K; MRC Protein Phosphorylation and Ubiquitylation Unit, Sir James Black Centre, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK. Electronic address: kpmlabib@dundee.ac.uk.
Publikováno v:
Cell reports [Cell Rep] 2017 Mar 28; Vol. 18 (13), pp. 3033-3042.