Zobrazeno 1 - 10
of 437
pro vyhledávání: '"Programmed cell death ligand 1 (PD-L1)"'
Publikováno v:
Journal of Cardiothoracic Surgery, Vol 19, Iss 1, Pp 1-6 (2024)
Abstract Background Primary cardiac angiosarcoma(PCA) has a low incidence rate and poor prognosis. Currently, no unified clinical treatment standards are available. Case presentation We report the case of a 48-year-old man presenting chest tightness,
Externí odkaz:
https://doaj.org/article/79660fedd80a463ba2b7c0e24cc28e09
Autor:
Ning Wang, Yu Jiang, Mengjie Li, Haofei Wang, Jie Pan, Yang Tang, Shaofang Xie, Yunyang Xu, Xu Li, Xuefei Zhou, Pinglong Xu, Wenlong Lin, Xiaojian Wang
Publikováno v:
Advanced Science, Vol 11, Iss 12, Pp n/a-n/a (2024)
Abstract Immunotherapy targeting PD‐L1 is still ineffective for a wide variety of tumors with high unpredictability. Deploying combined immunotherapy with alternative targeting is practical to overcome this therapeutic resistance. Here, the deficie
Externí odkaz:
https://doaj.org/article/8d4b8139261d460b99d832f6db8ea24a
Publikováno v:
Discover Oncology, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract More than 60 years ago, disulfiram (DSF) was employed for the management of alcohol addiction. This promising cancer therapeutic agent inhibits proliferation, migration, and invasion of malignant tumor cells. Furthermore, divalent copper ion
Externí odkaz:
https://doaj.org/article/e0af4016fd274b679bce579caf87b155
Autor:
Kensaku Matsui, Ryouji Tani, Sachiko Yamasaki, Nanako Ito, Atsuko Hamada, Tomoaki Shintani, Takeshi Otomo, Koichiro Tokumaru, Souichi Yanamoto, Tetsuji Okamoto
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 6077 (2024)
The impact of gut and oral microbiota on the clinical outcomes of patients with oral squamous cell carcinoma (OSCC) is unknown. We compared the bacterial composition of dental plaque and feces between patients with OSCC and healthy controls (HCs). Fe
Externí odkaz:
https://doaj.org/article/8f4dd1d18f664f06be55ffc8a5d5f708
Autor:
Kunyuan Wang, Chengxin Gu, Ganxiang Yu, Jiaen Lin, Zhilei Wang, Qianting Lu, Yangzhi Xu, Dan Zhao, Xiaofeng Jiang, Weijian Mai, Shiming Liu, Hui Yang
Publikováno v:
Liver Research, Vol 6, Iss 3, Pp 167-174 (2022)
Background and aims: Berberine is one of the most promising clinically tested natural alkaloids, and immunotherapy using natural killer (NK) cells is a potentially effective treatment for hepatocellular carcinoma (HCC). This study aims to elucidate t
Externí odkaz:
https://doaj.org/article/d6bbe99e06b3491b82e53f6ecbc13871
Autor:
Aiko Hirayama, Kentaro Tanaka, Hirono Tsutsumi, Takayuki Nakanishi, Sho Yamashita, Shun Mizusaki, Yumiko Ishii, Keiichi Ota, Yasuto Yoneshima, Eiji Iwama, Isamu Okamoto
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionProgrammed cell death–ligand 1 (PD-L1) is a biomarker for prediction of the clinical efficacy of immune checkpoint inhibitors in various cancer types. The role of cytokines in regulation of PD-L1 expression in tumor cells has not been f
Externí odkaz:
https://doaj.org/article/ac649d47542540b78dc3c41df09312dd
Autor:
Shujie Li, Yue Xie, Wei Zhou, Qian Zhou, Dan Tao, Haonan Yang, Kaijin Mao, Shi Li, Jinyan Lei, Yongzhong Wu, Ying Wang
Publikováno v:
Heliyon, Vol 9, Iss 6, Pp e16868- (2023)
Objective: To investigate the effect of MALAT1 on the modulating the radiosensitivity of lung adenocarcinoma, through regulation of the expression of the miR-140/PD-L1 axis. Methods: The online databases UALCAN and dbDEMC were searched for the MALAT1
Externí odkaz:
https://doaj.org/article/5ffd5d0244f94633b3dc195aa57c9b1d
Akademický článek
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Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-9 (2022)
Key points Baseline HBV loads do not affect the prognosis of HCC patients receiving anti-PD-1 in combination with antiangiogenic therapy. Besides, PD-1 inhibitors do not aggravate HBV reactivation and hepatic impairment undergoing concurrent TAF prop
Externí odkaz:
https://doaj.org/article/f2cb7053080949dc87d5066299cb2822
Publikováno v:
BMC Chemistry, Vol 16, Iss 1, Pp 1-20 (2022)
Abstract Small molecules are rising as a new generation of immune checkpoints’ inhibitors, with compounds targeting the human Programmed death-ligand 1 (hPD-L1) protein are pioneering this area of research. Promising examples include the recently d
Externí odkaz:
https://doaj.org/article/9dd16fb8fa3545478b38c725f03f9bab