Zobrazeno 1 - 10
of 402
pro vyhledávání: '"Programmed cell death 1- ligand 1"'
Autor:
Kazuki Yamagata, Masahiro Yanagawa, Akinori Hata, Ryo Ogawa, Noriko Kikuchi, Shuhei Doi, Keisuke Ninomiya, Yukiko Tokuda, Noriyuki Tomiyama
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract We examined the association between texture features using three-dimensional (3D) io-dine density histogram on delayed phase of dual-energy CT (DECT) and expression of programmed death-ligand 1 (PD-L1) using immunostaining methods in non-sma
Externí odkaz:
https://doaj.org/article/f910323114a94c35aa049304248c3efd
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The principle of immune checkpoint blockade therapy is based on the activation of T cells. Immune checkpoint inhibitors (ICIs), such as anti-PD-1/PD-L1 and anti-CTLA-4 antibodies, have demonstrated effectiveness in treating solid tumors by reinvigora
Externí odkaz:
https://doaj.org/article/b4f2038ecc8a4f0d8e24351ec1c56238
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-11 (2024)
Abstract Background Photodynamic therapy (PDT) is a promising interventional treatment approach that contributes to antitumor immunity. It has been reported that PDT can enhance the effectiveness of immune checkpoint inhibitors (ICIs), but its mechan
Externí odkaz:
https://doaj.org/article/d3b5edd027d04c0d9ce7584d39a5f7ee
Autor:
Magdalena Bojko, Katarzyna Węgrzyn, Emilia Sikorska, Piotr Ciura, Claire Battin, Peter Steinberger, Katarzyna Magiera-Mularz, Grzegorz Dubin, Adam Kulesza, Adam K. Sieradzan, Marta Spodzieja, Sylwia Rodziewicz-Motowidło
Publikováno v:
Translational Oncology, Vol 42, Iss , Pp 101892- (2024)
The PD-1/PD-L1 complex belongs to the group of inhibitory immune checkpoints and plays a critical role in immune regulation. The PD-1/PD-L1 axis is also responsible for immune evasion of cancer cells, and this complex is one of the main targets of im
Externí odkaz:
https://doaj.org/article/f56500fd70e44f229e66c4fb54d021eb
Publikováno v:
Cancer Medicine, Vol 12, Iss 8, Pp 9167-9174 (2023)
Abstract Background Hepatic failure induced by immune checkpoint inhibitors (ICIs) has been reported in only a few case series and case reports. Objective We aimed to explore the association between ICIs and hepatic failure and characterize the clini
Externí odkaz:
https://doaj.org/article/08a579c516f04808a8865450ade40ef1
Publikováno v:
Exploration of Medicine, Vol 3, Iss 6, Pp 592-606 (2022)
In a number of malignancies, new immuno-oncology therapies that focus on the programmed cell death 1 (PD-1) have improvised the patient condition along with a positive aftereffect. Monoclonal antibodies (mAbs) directed against PD-1 and its ligand (PD
Externí odkaz:
https://doaj.org/article/6b35af1ad83f42099fcb480357435038
Autor:
Linhan Zhang, Sheng Zhao, Huijie Jiang, Rongjun Zhang, Mingyu Zhang, Wenbin Pan, Zhongqi Sun, Dandan Wang, Jinping Li
Publikováno v:
EJNMMI Research, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Background Programmed cell death 1 ligand 1(PD-L1) is overexpressed in many tumors. The radionuclide-labeled anti-PD-L1 monoclonal antibody can be used for imaging and therapy of PD-L1 overexpressing cancer. Here, we described 131I-labeled A
Externí odkaz:
https://doaj.org/article/1ba988638baf42d6ad293ac0b456a436
Publikováno v:
Thoracic Cancer, Vol 13, Iss 19, Pp 2669-2680 (2022)
Abstract With the in‐depth understanding of programmed cell death 1 ligand 1 (PD‐L1) in non‐small cell lung cancer (NSCLC), PD‐L1 has become a vital immunotherapy target and a significant biomarker. The clinical utility of detecting PD‐L1 b
Externí odkaz:
https://doaj.org/article/fb91215f9ade4ed1b6701ee9d1c50244
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Akademický článek
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